Test Bank For Genetics and Genomics in
nh nh nh nh nh nh
Nursing and Health Care 2nd Edition By
nh nh nh nh nh nh nh
Theresa A. Beery
nh nh nh
, Stuvia.com - The Marketplace to Buy and Sell your Study nh nh nh nh nh nh nh nh nh
Material
Chapter 1: DNA Structure and Function
nh nh nh nh nh
Multiple Choice
nh
Identify the choice that best completes the statement or answers the question.
nh nh nh nh nh nh nh nh nh nh nh
1. n h n h In which body or cell area arenmost genes in humans located?
nh nh nh nh nh nh nh nh nh nh
A. Nucleus
B. Mitochondrion
C. Cytoplasm
D. Plasma membrane nh
2. n h n h Which condition or statement exemplifies thenconcept of genomics rather than genetics?
nh nh nh nh nh nh nh nh nh nh
A. The gene for insulin is located on chromosome 11 innall people.
nh nh nh nh nh nh nh nh nh nh
B. Expression of any single gene is dependent on inheriting twonalleles. nh nh nh nh nh nh nh nh nh
C. Sex-linked recessive disorders affect males morenoften than females. nh nh nh nh nh nh nh
D. Onenallele for eachngenenis inherited from the mother, and onenis inherited from the f
nh nh nh nh nh nh nh nh nh nh nh nh
ather. nh
3. n h n h What is the purpose of phosphorous in a DNA strand?
nh nh nh nh nh nh nh nh nh
A. Linking the nucleotides into anstrand nh nh nh nh
B. Holding complementary strands together nh nh nh
C. Ensuring that a purine is always paired with a pyrimidinenh nh nh nh nh nh nh nh nh
D. Preventingnthenseparation of double-stranded DNA into single-stranded DNA nh nh nh nh nh nh
GRADESMORE.COM
4. n h What is the term used to define alternative forms of a gene that may result in different expression of
n h nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh
the trait coded for by that gene?
nh nh nh nh nh nh
A. Alleles
B. Bases
C. Centromeres
D. Diploids
5. n h What percentage of bases in a stretch of double-
n h nh nh nh nh nh nh nh nh
stranded DNA that contains 30%nguanine (G) bases would be adenine (A)?
nh nh nh nh nh nh nh nh nh nh
A. 70%
B. 60%
C. 30%
D. 20%
6. n hWhat is the term used to describe the organized picture of the paired chromosomes within a cell used t
nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh
o determine whether chromosomennumbers, structures, and bandingnpatterns are normal?
nh nh nh nh nh nh nh nh nh
A. Pedigree
B. Phenotype
C. Karyotype
D. Autotype
7. n What would benthensequence of DNA that is complementary to a DNA section with thenbase s
h nh nh nh nh nh nh nh nh nh nh nh nh nh nh
equence of GGTCAATCCTTAG?
nh nh nh
A. GATTCCTAACTGG
Copyright © 2018 F. A. Davis Company nh nh nh nh nh nh
WWW.NURSYLAB.COM
GRADESMORE.COM
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Material
B. TTGACCGAAGGCT
C. AACTGGCTTCCGA
D. CCAGTTAGGAATC
8. n h n h Which of these complementary base pairs formnthe strongest or “tightest” association?
nh nh nh nh nh nh nh nh nh nh
A. Adenine and thymine nh nh
B. Cytosine and guanine nh nh
C. Guanine and thymine nh nh
D. Cytosine and adenine nh nh
9. n h n h What activity occurs during M phasenof the cell cycle?
nh nh nh nh nh nh nh nh
A. The cell undergoes cytokinesis.
nh nh nh
B. Activity stops, and the cell “sleeps.” nh nh nh nh nh
C. All DNA is completely replicated.
nh nh nh nh
D. The cell greatly increases protein synthesis.
nh nh nh nh nh
n h 10. n h n h Which chromosome number represents the euploid state for normal human somatic cells?
nh nh nh nh nh nh nh nh nh nh nh
A. 44
B. 46
C. 47
D. 48
n h 11. nHow does thenproteome differ from thengenome?
h nh nh nh nh nh
A. The proteome changes in response to intracellular and extracellular signals.
nh nh nh nh nh nh nh nh nh
B. Then genomen changesn inn respoGnR
nh seAtD
oEinStrM
acOeR
lluEla.rCaO
ndMextracellular signals.
nh nh nh nh n h
C. Thenproteome is stable in somatic cells and unstable in germ cells, whereas the nh nh nh nh nh nh nh nh nh nh nh nh
genome is stable innboth somatic cellsnand germ cells.
nh nh nh nh nh nh nh
D. The genome is stable in somatic cells and unstable in germ cells, whereas the
nh nh nh nh nh nh nh nh nh nh nh nh nh
proteome is stable in both somatic cells andngerm cells.
nh nh nh nh nh nh nh nh nh
n h 12. n h n h What is the most outstandingnfeature of a mature haploid cell?
nh nh nh nh nh nh nh nh nh
A. It is usually homozygous.
nh nh nh
B. The sex chromosomes are missing.
nh nh nh nh
C. Only one chromosome of each pair is present.
nh nh nh nh nh nh nh
D. DNA synthesis occurs after mitosis insteadnof before.
nh nh nh nh nh nh
n h 13. n h n h At what phase of thencell cycle are chromosomes visiblenas separate structures?
nh nh nh nh nh nh nh nh nh nh
A. G1
B. G2
C. S
D. M
n h 14. n h n h Which statement about the cell cycle phase of G0 is true?
nh nh nh nh nh nh nh nh nh nh
A. Hyperplastic growth in place of hypertrophic growth nh nh nh nh nh nh
B. Performance of specific differentiated functions nh nh nh nh
C. Initiation and completion of nucleokinesis nh nh nh nh
D. Replication of DNA nh nh
n h 15. n h n h What is the result of normal DNA replication?
nh nh nh nh nh nh nh
Copyright © 2018 F. A. Davis Company nh nh nh nh nh nh
WWW.NURSYLAB.COM
GRADESMORE.COM
, Stuvia.com - The Marketplace to Buy and Sell your Study nh nh nh nh nh nh nh nh nh
Material
A. Formation of two new daughter cells nh nh nh nh nh
B. Formation of two identical sets of DNA nh nh nh nh nh nh
C. Disappearance of the original parent cell nh nh nh nh nh
D. Activation and attachment of spindle fibers nh nh nh nh nh
16. Which statement regardingnchromosome structure or function is true?
nh nh nh nh nh nh nh
A. Thenchromatids of any single chromosome are known as “sister chromatids.” nh nh nh nh nh nh nh nh nh
B. The genes located on thentelomeres of chromosomes are identical to the genes in t
nh nh nh nh nh nh nh nh nh nh nh nh nh
nh he centromeres.
nh
C. Immediately beforenthenmitosis phase of cell division, the chromosomes of all s nh nh nh nh nh nh nh nh nh nh
nh omatic cells are haploid. nh nh nh
D. A specific gene allele on onenchromosome has a complementary allele onnthe other c
nh nh nh nh nh nh nh nh nh nh nh nh
nh hromosome of a pair. nh nh nh
17. Why does a person with normal chromosomes only have two alleles for any single gene trait?
nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh
A. A minimumnof two alleles is required for the expression of monogenic traits.
nh nh nh nh nh nh nh nh nh nh nh
B. Whenna dominant allele is paired withna recessivenallele, only the dominant allele is e
nh nh nh nh nh nh nh nh nh nh nh nh
xpressed, and the recessive allele is silent.
nh nh nh nh nh nh nh
C. One allele for the monogenic trait is on the paternally derived chromosome, and the
nh nh nh nh nh nh nh nh nh nh nh nh nh
other allele is on the maternally derived chromosome.
nh nh nh nh nh nh nh nh
D. Expression of more than two alleles of any single- nh nh nh nh nh nh nh nh
gene trait results innenhanced expression of recessive alleles and suppressed expres
nh nh nh nh nh nh nh nh nh nh
sion of dominant alleles.
nh nh nh nh
n h 18. n h n h Under what normal condition arengenotype and phenotype always the same?
nh nh nh nh nh nh nh nh nh
A. Euploidy of alleles GRADESMORE.COM nh nh
B. Aneuploidy of alleles nh nh
C. Homozygosity of alleles nh nh
D. Heterozygosity of alleles nh nh
n h 19. n What would be the expected result of a drugnthat affected anparticular tissuenby causing new DNA
h nh nh nh nh nh nh nh nh nh nh nh nh nh nh
tonfo rm with covalent bonds instead of hydrogennbonds?
nh nh nh nh nh nh nh nh
A. None of the cells in the affected tissue would be able to leavenG0n and enter the cell c
nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh
ycle. nh
B. Replication of DNA would result in identical DNA strands insteadnof complementa nh nh nh nh nh nh nh nh nh nh
ry strands. nh nh
C. Mitosis of cells innthentissue wouldnresultninnthenproduction of threennew daughter ce
nh nh nh nh nh nh nh nh
lls instead of just two.
nh nh nh nh nh
D. The new cells that formed within this tissue would not benable to complete the next round
nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh
of mitosis successfully.
nh nh nh
n h 20. How does the DNA enzyme topoisomerase contribute to DNA replication?
n h n h nh nh nh nh nh nh nh nh nh
A. Unwinds the double helix and separates thendouble-stranded DNA nh nh nh nh nh nh nh
B. Creates a “nick” in the DNA supercoils, allowingnthem to straighten before
nh nh nh nh nh nh nh nh nh nh
replication
nh
C. Initiates DNA synthesis in multiple sites down the strand, makingnthenprocess more
nh nh nh nh nh nh nh nh nh nh
efficient nh
D. Connects and links the individual pieces of newly synthesized DNA to form a
nh nh nh nh nh nh nh nh nh nh nh nh
singlenstrand
nh
Copyright © 2018 F. A. Davis Company nh nh nh nh nh nh
WWW.NURSYLAB.COM
GRADESMORE.COM
nh nh nh nh nh nh
Nursing and Health Care 2nd Edition By
nh nh nh nh nh nh nh
Theresa A. Beery
nh nh nh
, Stuvia.com - The Marketplace to Buy and Sell your Study nh nh nh nh nh nh nh nh nh
Material
Chapter 1: DNA Structure and Function
nh nh nh nh nh
Multiple Choice
nh
Identify the choice that best completes the statement or answers the question.
nh nh nh nh nh nh nh nh nh nh nh
1. n h n h In which body or cell area arenmost genes in humans located?
nh nh nh nh nh nh nh nh nh nh
A. Nucleus
B. Mitochondrion
C. Cytoplasm
D. Plasma membrane nh
2. n h n h Which condition or statement exemplifies thenconcept of genomics rather than genetics?
nh nh nh nh nh nh nh nh nh nh
A. The gene for insulin is located on chromosome 11 innall people.
nh nh nh nh nh nh nh nh nh nh
B. Expression of any single gene is dependent on inheriting twonalleles. nh nh nh nh nh nh nh nh nh
C. Sex-linked recessive disorders affect males morenoften than females. nh nh nh nh nh nh nh
D. Onenallele for eachngenenis inherited from the mother, and onenis inherited from the f
nh nh nh nh nh nh nh nh nh nh nh nh
ather. nh
3. n h n h What is the purpose of phosphorous in a DNA strand?
nh nh nh nh nh nh nh nh nh
A. Linking the nucleotides into anstrand nh nh nh nh
B. Holding complementary strands together nh nh nh
C. Ensuring that a purine is always paired with a pyrimidinenh nh nh nh nh nh nh nh nh
D. Preventingnthenseparation of double-stranded DNA into single-stranded DNA nh nh nh nh nh nh
GRADESMORE.COM
4. n h What is the term used to define alternative forms of a gene that may result in different expression of
n h nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh
the trait coded for by that gene?
nh nh nh nh nh nh
A. Alleles
B. Bases
C. Centromeres
D. Diploids
5. n h What percentage of bases in a stretch of double-
n h nh nh nh nh nh nh nh nh
stranded DNA that contains 30%nguanine (G) bases would be adenine (A)?
nh nh nh nh nh nh nh nh nh nh
A. 70%
B. 60%
C. 30%
D. 20%
6. n hWhat is the term used to describe the organized picture of the paired chromosomes within a cell used t
nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh
o determine whether chromosomennumbers, structures, and bandingnpatterns are normal?
nh nh nh nh nh nh nh nh nh
A. Pedigree
B. Phenotype
C. Karyotype
D. Autotype
7. n What would benthensequence of DNA that is complementary to a DNA section with thenbase s
h nh nh nh nh nh nh nh nh nh nh nh nh nh nh
equence of GGTCAATCCTTAG?
nh nh nh
A. GATTCCTAACTGG
Copyright © 2018 F. A. Davis Company nh nh nh nh nh nh
WWW.NURSYLAB.COM
GRADESMORE.COM
, Stuvia.com - The Marketplace to Buy and Sell your Study nh nh nh nh nh nh nh nh nh
Material
B. TTGACCGAAGGCT
C. AACTGGCTTCCGA
D. CCAGTTAGGAATC
8. n h n h Which of these complementary base pairs formnthe strongest or “tightest” association?
nh nh nh nh nh nh nh nh nh nh
A. Adenine and thymine nh nh
B. Cytosine and guanine nh nh
C. Guanine and thymine nh nh
D. Cytosine and adenine nh nh
9. n h n h What activity occurs during M phasenof the cell cycle?
nh nh nh nh nh nh nh nh
A. The cell undergoes cytokinesis.
nh nh nh
B. Activity stops, and the cell “sleeps.” nh nh nh nh nh
C. All DNA is completely replicated.
nh nh nh nh
D. The cell greatly increases protein synthesis.
nh nh nh nh nh
n h 10. n h n h Which chromosome number represents the euploid state for normal human somatic cells?
nh nh nh nh nh nh nh nh nh nh nh
A. 44
B. 46
C. 47
D. 48
n h 11. nHow does thenproteome differ from thengenome?
h nh nh nh nh nh
A. The proteome changes in response to intracellular and extracellular signals.
nh nh nh nh nh nh nh nh nh
B. Then genomen changesn inn respoGnR
nh seAtD
oEinStrM
acOeR
lluEla.rCaO
ndMextracellular signals.
nh nh nh nh n h
C. Thenproteome is stable in somatic cells and unstable in germ cells, whereas the nh nh nh nh nh nh nh nh nh nh nh nh
genome is stable innboth somatic cellsnand germ cells.
nh nh nh nh nh nh nh
D. The genome is stable in somatic cells and unstable in germ cells, whereas the
nh nh nh nh nh nh nh nh nh nh nh nh nh
proteome is stable in both somatic cells andngerm cells.
nh nh nh nh nh nh nh nh nh
n h 12. n h n h What is the most outstandingnfeature of a mature haploid cell?
nh nh nh nh nh nh nh nh nh
A. It is usually homozygous.
nh nh nh
B. The sex chromosomes are missing.
nh nh nh nh
C. Only one chromosome of each pair is present.
nh nh nh nh nh nh nh
D. DNA synthesis occurs after mitosis insteadnof before.
nh nh nh nh nh nh
n h 13. n h n h At what phase of thencell cycle are chromosomes visiblenas separate structures?
nh nh nh nh nh nh nh nh nh nh
A. G1
B. G2
C. S
D. M
n h 14. n h n h Which statement about the cell cycle phase of G0 is true?
nh nh nh nh nh nh nh nh nh nh
A. Hyperplastic growth in place of hypertrophic growth nh nh nh nh nh nh
B. Performance of specific differentiated functions nh nh nh nh
C. Initiation and completion of nucleokinesis nh nh nh nh
D. Replication of DNA nh nh
n h 15. n h n h What is the result of normal DNA replication?
nh nh nh nh nh nh nh
Copyright © 2018 F. A. Davis Company nh nh nh nh nh nh
WWW.NURSYLAB.COM
GRADESMORE.COM
, Stuvia.com - The Marketplace to Buy and Sell your Study nh nh nh nh nh nh nh nh nh
Material
A. Formation of two new daughter cells nh nh nh nh nh
B. Formation of two identical sets of DNA nh nh nh nh nh nh
C. Disappearance of the original parent cell nh nh nh nh nh
D. Activation and attachment of spindle fibers nh nh nh nh nh
16. Which statement regardingnchromosome structure or function is true?
nh nh nh nh nh nh nh
A. Thenchromatids of any single chromosome are known as “sister chromatids.” nh nh nh nh nh nh nh nh nh
B. The genes located on thentelomeres of chromosomes are identical to the genes in t
nh nh nh nh nh nh nh nh nh nh nh nh nh
nh he centromeres.
nh
C. Immediately beforenthenmitosis phase of cell division, the chromosomes of all s nh nh nh nh nh nh nh nh nh nh
nh omatic cells are haploid. nh nh nh
D. A specific gene allele on onenchromosome has a complementary allele onnthe other c
nh nh nh nh nh nh nh nh nh nh nh nh
nh hromosome of a pair. nh nh nh
17. Why does a person with normal chromosomes only have two alleles for any single gene trait?
nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh
A. A minimumnof two alleles is required for the expression of monogenic traits.
nh nh nh nh nh nh nh nh nh nh nh
B. Whenna dominant allele is paired withna recessivenallele, only the dominant allele is e
nh nh nh nh nh nh nh nh nh nh nh nh
xpressed, and the recessive allele is silent.
nh nh nh nh nh nh nh
C. One allele for the monogenic trait is on the paternally derived chromosome, and the
nh nh nh nh nh nh nh nh nh nh nh nh nh
other allele is on the maternally derived chromosome.
nh nh nh nh nh nh nh nh
D. Expression of more than two alleles of any single- nh nh nh nh nh nh nh nh
gene trait results innenhanced expression of recessive alleles and suppressed expres
nh nh nh nh nh nh nh nh nh nh
sion of dominant alleles.
nh nh nh nh
n h 18. n h n h Under what normal condition arengenotype and phenotype always the same?
nh nh nh nh nh nh nh nh nh
A. Euploidy of alleles GRADESMORE.COM nh nh
B. Aneuploidy of alleles nh nh
C. Homozygosity of alleles nh nh
D. Heterozygosity of alleles nh nh
n h 19. n What would be the expected result of a drugnthat affected anparticular tissuenby causing new DNA
h nh nh nh nh nh nh nh nh nh nh nh nh nh nh
tonfo rm with covalent bonds instead of hydrogennbonds?
nh nh nh nh nh nh nh nh
A. None of the cells in the affected tissue would be able to leavenG0n and enter the cell c
nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh
ycle. nh
B. Replication of DNA would result in identical DNA strands insteadnof complementa nh nh nh nh nh nh nh nh nh nh
ry strands. nh nh
C. Mitosis of cells innthentissue wouldnresultninnthenproduction of threennew daughter ce
nh nh nh nh nh nh nh nh
lls instead of just two.
nh nh nh nh nh
D. The new cells that formed within this tissue would not benable to complete the next round
nh nh nh nh nh nh nh nh nh nh nh nh nh nh nh
of mitosis successfully.
nh nh nh
n h 20. How does the DNA enzyme topoisomerase contribute to DNA replication?
n h n h nh nh nh nh nh nh nh nh nh
A. Unwinds the double helix and separates thendouble-stranded DNA nh nh nh nh nh nh nh
B. Creates a “nick” in the DNA supercoils, allowingnthem to straighten before
nh nh nh nh nh nh nh nh nh nh
replication
nh
C. Initiates DNA synthesis in multiple sites down the strand, makingnthenprocess more
nh nh nh nh nh nh nh nh nh nh
efficient nh
D. Connects and links the individual pieces of newly synthesized DNA to form a
nh nh nh nh nh nh nh nh nh nh nh nh
singlenstrand
nh
Copyright © 2018 F. A. Davis Company nh nh nh nh nh nh
WWW.NURSYLAB.COM
GRADESMORE.COM
