1
1
H-NMR – Theory, Numbers of signals, and Chemical shifts
1
H-NMR Spectroscopy
Magnetic Resonance Imaging (MRI)
1
H NMR vs 13C NMR - Differences
2) Integration
3) Spin multiplicity
Scale 12-0
Scale 220-0
Me when my friend says that the lab report is due an hour ago
, 1
2
H-NMR – Theory, Numbers of signals, and Chemical shifts
Info#1 Number of signals
▪ Number of chemically non-equivalent proton (1H)
▪ Watch out!
• Symmetry makes protons chemically “equivalent” (same)
I signal
z signal 2 signal
• Stereochemistry makes protons chemically “non-equivalent” (different)
4 signal
Dif . enviro
Back phase
Moser
is closer to
+8 Dif. OH
enviro
mething group
Chirality affects the electronic environment of CH2 but not CH3 (end hydrogen)
Back phase
is closer to
OH
3 dif .
Signals
Me when my friend says that the lab report is due an hour ago
1
H-NMR – Theory, Numbers of signals, and Chemical shifts
1
H-NMR Spectroscopy
Magnetic Resonance Imaging (MRI)
1
H NMR vs 13C NMR - Differences
2) Integration
3) Spin multiplicity
Scale 12-0
Scale 220-0
Me when my friend says that the lab report is due an hour ago
, 1
2
H-NMR – Theory, Numbers of signals, and Chemical shifts
Info#1 Number of signals
▪ Number of chemically non-equivalent proton (1H)
▪ Watch out!
• Symmetry makes protons chemically “equivalent” (same)
I signal
z signal 2 signal
• Stereochemistry makes protons chemically “non-equivalent” (different)
4 signal
Dif . enviro
Back phase
Moser
is closer to
+8 Dif. OH
enviro
mething group
Chirality affects the electronic environment of CH2 but not CH3 (end hydrogen)
Back phase
is closer to
OH
3 dif .
Signals
Me when my friend says that the lab report is due an hour ago
