Brooker Genetics – Comprehensive Final Exam Review with Practice
Questions and Correct answers for Mendelian Inheritance, Molecular
Genetics, Gene Expression, and Biotechnology
A) 63 chromosomes
B) Mules would be sterile - one chromosome will be unpaired resulting in some gametes being
short a chromosome and others having an extra chromosome. - correct answer The diploid
number of a horse (Equus caballus) is 64 which includes 36 acrocentric autosomes. The donkey
(Equus asinus) has 62 chromosomes including 22 acrocentric autosomes.
A) Predict the number of chromosomes that would be found in the hybrid offspring (mule)
produced by mating a male donkey (jack) to a female horse (mare).
B) Why are mules usually sterile (incapable of producing viable gametes)?
presymptomatic testing is possible. - correct answer One way that genetic diseases differ from
other diseases is:
0.5x0.5x0.5 = 0.125 or 1/8 - correct answer If a couple is planning on having three children,
what is the probability that all 3 will be male?
Pleiotropy - correct answer A particular gene that controls seed coat color in peas also
determines the susceptibility of these peas to a particular disease. This situation is referred to
as ______ where one gene regulates more than one phenotype.
½ A : ½ B blood types - correct answer What are the possible phenotypes of children whose
mother's genotype is ii for blood type and the father is IA IB
protects the mRNA from degradation and assists in ribosome binding during translation. -
correct answer A 5' 7-methyl-guanosine cap on a molecule of mRNA:
Messenger RNA only - correct answer What is the final product of transcription?
15 - correct answer If the diploid number of an organism is 30, how many chromosomes will be
present in a cell following meiosis?
1 -mRNA leader sequence (5' UTR) binds to rRNA in small subunit of ribosome
2 - Large ribosomal subunit binds initiation complex
, 3 - tRNA binds to A site based on codon complementarity, adding amino acid to growing
peptide
4 - Stop codon is reached terminating synthesis of the polypeptide - correct answer Place the
following events of translation in the correct sequence.
nonsense mutation - correct answer A substitution of one base pair for another that results in
the conversion of an amino acid specifying codon to a termination codon is called a _____
mutation.
It is the product of transcription - correct answer Which of the following properties are
exclusive to mRNA?
All of the following statements are true EXCEPT: - correct answer **Movement of a proto-
oncogene next to a highly transcribed gene can lead to erroneous transcription
Checkpoints during the cell cycle monitor the integrity of DNA and can induce apoptosis if DNA
repairs are not or cannot be made
All tumors that divide continually despite cellular signals are malignant
A fusion gene can result in a protein that abnormally signals cell division
p53 is a gene that regulates the cell cycle
Cosmid
BAC
Plasmid
YAC
**ORI - correct answer Which of the following is not a cloning vector?
Which of the following statements is true? - correct answer **Chromatin can be visualized
during interphase
The Y-chromosome is much longer (shorter) than the X-chromosome in humans
Questions and Correct answers for Mendelian Inheritance, Molecular
Genetics, Gene Expression, and Biotechnology
A) 63 chromosomes
B) Mules would be sterile - one chromosome will be unpaired resulting in some gametes being
short a chromosome and others having an extra chromosome. - correct answer The diploid
number of a horse (Equus caballus) is 64 which includes 36 acrocentric autosomes. The donkey
(Equus asinus) has 62 chromosomes including 22 acrocentric autosomes.
A) Predict the number of chromosomes that would be found in the hybrid offspring (mule)
produced by mating a male donkey (jack) to a female horse (mare).
B) Why are mules usually sterile (incapable of producing viable gametes)?
presymptomatic testing is possible. - correct answer One way that genetic diseases differ from
other diseases is:
0.5x0.5x0.5 = 0.125 or 1/8 - correct answer If a couple is planning on having three children,
what is the probability that all 3 will be male?
Pleiotropy - correct answer A particular gene that controls seed coat color in peas also
determines the susceptibility of these peas to a particular disease. This situation is referred to
as ______ where one gene regulates more than one phenotype.
½ A : ½ B blood types - correct answer What are the possible phenotypes of children whose
mother's genotype is ii for blood type and the father is IA IB
protects the mRNA from degradation and assists in ribosome binding during translation. -
correct answer A 5' 7-methyl-guanosine cap on a molecule of mRNA:
Messenger RNA only - correct answer What is the final product of transcription?
15 - correct answer If the diploid number of an organism is 30, how many chromosomes will be
present in a cell following meiosis?
1 -mRNA leader sequence (5' UTR) binds to rRNA in small subunit of ribosome
2 - Large ribosomal subunit binds initiation complex
, 3 - tRNA binds to A site based on codon complementarity, adding amino acid to growing
peptide
4 - Stop codon is reached terminating synthesis of the polypeptide - correct answer Place the
following events of translation in the correct sequence.
nonsense mutation - correct answer A substitution of one base pair for another that results in
the conversion of an amino acid specifying codon to a termination codon is called a _____
mutation.
It is the product of transcription - correct answer Which of the following properties are
exclusive to mRNA?
All of the following statements are true EXCEPT: - correct answer **Movement of a proto-
oncogene next to a highly transcribed gene can lead to erroneous transcription
Checkpoints during the cell cycle monitor the integrity of DNA and can induce apoptosis if DNA
repairs are not or cannot be made
All tumors that divide continually despite cellular signals are malignant
A fusion gene can result in a protein that abnormally signals cell division
p53 is a gene that regulates the cell cycle
Cosmid
BAC
Plasmid
YAC
**ORI - correct answer Which of the following is not a cloning vector?
Which of the following statements is true? - correct answer **Chromatin can be visualized
during interphase
The Y-chromosome is much longer (shorter) than the X-chromosome in humans
