Immunology – Comprehensive Final Exam Review with Practice
Questions and Correct answers for Innate and Adaptive Immunity,
Antibodies, Vaccines, and Immune Disorders
Which of the following elements of the immune system is not considered part of the innate
systems second line of defense?
Phagocytic leukocytes
Fever induction
B cells
Antimicrobial proteins - correct answer B cells
Some populations of T-cells able to interact with self antigens during negative selection will be
destined to become:
T reg cells
Cytotoxic Killer T cells
Helper T cells
Natural Killer cells - correct answer T reg cells
Which of the following enzymes help phagocytic cells in the digestion of particles?
Lysozymes
Major Basic Protein
Heparin
Histamines - correct answer Lysozymes
Phagocytic cell:
Eosinophil
Mast cell
Dendritic cell
,Basophil - correct answer Dendritic cell
What chemical messenger(chemokine) is responsible for aiding the body in host-defense
functions against viruses?
IgG
IgM
Interferon
Tumor necrosis factor - correct answer Interferon
This cell can only be activated by a IgE sensitized Mast cell:
Neutrophil
Basophil
Eosinophil
Macrophage - correct answer Basophil
Cell lacks the MHC I receptor and is CD3- and CD56+ and uses granzymes to induce apoptosis.
Neutrophil
Eosinophil
Dendritic cell
NK cell - correct answer NK cell
Every true lymphocyte in the adaptive immune response will possess which CD marker in their
cell membrane?
CD8
CD56
CD3
CD4 - correct answer CD3
,Considered an intermediary between the adaptive and innate responses, these cells reside in
the skin, the inner lining of the nose, stomach, intestines, and presents antigens in the lymph
nodes.
T helper cell
Neutrophil
Monocyte
Dendritic cell - correct answer Dendritic cell
Secondary lymphoid tissue found in the gut:
Peyers patches
Thymus
BALT
Spleen - correct answer Peyers patches
Receptors of the innate immune system that recognizes common foreign pathogens:
Major histocompatibility receptors
Pathogen associated molecular patterns
Pattern recognition receptors
CD antigens - correct answer Pattern recognition receptors
In the secondary immune response, which class of antibody predominates over the others in
terms of overall concentration?
IgE
IgA
gG
IgM - correct answer IgG
What is the lag time for b cell involvement in the primary immune response?
, 1-3 days
7-10 days
>10 days
4-7 days - correct answer 4-7 days
In the secondary, anamnestic response, what type of cell has major immune involvement?
Naïve B cell
Plasma cell
Memory B cell
Memory T cell - correct answer Memory B cell
Secondary lymphoid tissue:
Liver
Lymph nodes
Thymus
Bone Marrow - correct answer Lymph nodes
Concept defined in which B cells develop more specific and better fitting antibodies as they
come into subsequent encounters with antigen over time?
Chemotaxis
Gene rearrangement
Class switching
Affinity maturation - correct answer Affinity maturation
Contact with L-selectin white cell surface receptors with a promoted Sialyl-Lewis X epithelial
receptor will initiate what change?
Questions and Correct answers for Innate and Adaptive Immunity,
Antibodies, Vaccines, and Immune Disorders
Which of the following elements of the immune system is not considered part of the innate
systems second line of defense?
Phagocytic leukocytes
Fever induction
B cells
Antimicrobial proteins - correct answer B cells
Some populations of T-cells able to interact with self antigens during negative selection will be
destined to become:
T reg cells
Cytotoxic Killer T cells
Helper T cells
Natural Killer cells - correct answer T reg cells
Which of the following enzymes help phagocytic cells in the digestion of particles?
Lysozymes
Major Basic Protein
Heparin
Histamines - correct answer Lysozymes
Phagocytic cell:
Eosinophil
Mast cell
Dendritic cell
,Basophil - correct answer Dendritic cell
What chemical messenger(chemokine) is responsible for aiding the body in host-defense
functions against viruses?
IgG
IgM
Interferon
Tumor necrosis factor - correct answer Interferon
This cell can only be activated by a IgE sensitized Mast cell:
Neutrophil
Basophil
Eosinophil
Macrophage - correct answer Basophil
Cell lacks the MHC I receptor and is CD3- and CD56+ and uses granzymes to induce apoptosis.
Neutrophil
Eosinophil
Dendritic cell
NK cell - correct answer NK cell
Every true lymphocyte in the adaptive immune response will possess which CD marker in their
cell membrane?
CD8
CD56
CD3
CD4 - correct answer CD3
,Considered an intermediary between the adaptive and innate responses, these cells reside in
the skin, the inner lining of the nose, stomach, intestines, and presents antigens in the lymph
nodes.
T helper cell
Neutrophil
Monocyte
Dendritic cell - correct answer Dendritic cell
Secondary lymphoid tissue found in the gut:
Peyers patches
Thymus
BALT
Spleen - correct answer Peyers patches
Receptors of the innate immune system that recognizes common foreign pathogens:
Major histocompatibility receptors
Pathogen associated molecular patterns
Pattern recognition receptors
CD antigens - correct answer Pattern recognition receptors
In the secondary immune response, which class of antibody predominates over the others in
terms of overall concentration?
IgE
IgA
gG
IgM - correct answer IgG
What is the lag time for b cell involvement in the primary immune response?
, 1-3 days
7-10 days
>10 days
4-7 days - correct answer 4-7 days
In the secondary, anamnestic response, what type of cell has major immune involvement?
Naïve B cell
Plasma cell
Memory B cell
Memory T cell - correct answer Memory B cell
Secondary lymphoid tissue:
Liver
Lymph nodes
Thymus
Bone Marrow - correct answer Lymph nodes
Concept defined in which B cells develop more specific and better fitting antibodies as they
come into subsequent encounters with antigen over time?
Chemotaxis
Gene rearrangement
Class switching
Affinity maturation - correct answer Affinity maturation
Contact with L-selectin white cell surface receptors with a promoted Sialyl-Lewis X epithelial
receptor will initiate what change?
