Chapter 1: Introduction
Chapter 2: The Dynamics of Disease Transmission
Chapter 3: The Occurrence of Disease: I. Disease Surveillance and Measures of Morbidity
Chapter 4: The Occurrence of Disease: II. Mortality and Other Measures of Disease
Impact
Chapter 5: Assessing the Validity and Reliability of Diagnostic and Screening Tests
Chapter 6: The Natural History of Disease: Ways of Expressing Prognosis
Chapter 7: Observational Studies
Chapter 8: Cohort Studies
Chapter 9: Comparing Cohort and Case-Control Studies
Chapter 10: Assessing Preventive and Therapeutic Measures: Randomized Trials
Chapter 11: Randomized Trials: Some Further Issues
Chapter 12: Estimating Risk: Is There an Association?
Chapter 13: More on Risk: Estimating the Potential for Prevention
Chapter 14: From Association to Causation: Deriving Inferences From Epidemiologic
Studies
Chapter 15: More on Causal Inference: Bias, Confounding, and Interaction
Chapter 16: Identifying the Roles of Genetic and Environmental Factors in Disease
Causation
Chapter 17: Using Epidemiology to Evaluate Health Services
Chapter 18: Epidemiologic Approach to Evaluating Screening Programs
Chapter 19: Epidemiology and Public Policy
Chapter 20: Ethical and Professional Issues in Epidemiology
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, Chapter 01: Introduction
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Celentano: Gordis Epidemiology, 6th Edition
Test Bank abirb.com/test
MULTIPLE CHOICE
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1. Which of the following is an example of tertiary prevention?
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a. Vaccination for rotavirus for children younger than the age of 1 year
b. Surgical amputation of an extremity with osteosarcoma (bone cancer)
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c. Screening for gestational diabetes after 24 weeks of pregnancy
d. Sexual education program in elementary schools
e. Increasing taxes for buying cigarettes
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ANS: B
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Surgical amputation of an extremity with osteosarcoma (bone cancer) is an example in which
when a disease is present the treatment (amputation) is done to reduce the impact of disease
by preventing the tumor from dissemination. Vaccinationabirb.com/test
for rotavirus for children younger
than the age of 1 year, sexual education program in elementary schools, and increasing taxes
for buying cigarettes represent examples of primary prevention. Screening for gestational
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diabetes after 24 weeks of pregnancy is an example of secondary prevention.
2. This historic character observed that childbed fever mortality was more common among
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women treated by physicians and medical students compared with women treated by
midwives. Based on his observations, he implemented a hand wash policy that resulted in a
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decrease in mortality. Name the character that we are talking about.
a. John Snow abirb.com/test
b. Edward Jenner
c. D.A. Henderson
d. Leon Gordis abirb.com/test
e. Ignaz Semmelweis
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ANS: E
Ignaz Semmelweis identified that medical students and physicians transmitted the disease by
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not washing their hands after examining bodies at autopsies and conducting multiple
examinations in the clinic.
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3. Thanks to the contributions of Edward Jenner, the following disease was eradicated later
by efforts organized by D.A. Henderson: abirb.com/test
a. Cholera
b. Smallpox abirb.com/test
c. Chickenpox
d. Polio abirb.com/test
e. Zika
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, Test Bank 1-2
ANS: B
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Smallpox was eradicated in 1980. Edward Jenner vaccinated James Phipps in 1796 against
smallpox. Almost 200 years later, the World Health Organization (WHO) commissioned
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D.A. Henderson to lead the efforts to eradicate the disease.
4. Over the past century, a marked decline in the mortality abirb.com/test
rates of many infectious diseases
has been observed. Which of the following is the most likely reason for the observed decline
in mortality rates from common infectious diseases?
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a. Development of penicillin
b. Development of insulin abirb.com/test
c. Development of vaccines
d. Improvement in social conditions
e. Worse sanitation and unsafe water abirb.com/test
ANS: D abirb.com/test
Although medical treatments potentially helped in the decrease of infectious diseases, the
advancement in social conditions played a major role. These abirb.com/test
improvements include better
sanitation, safe disposal of waste, better nutrition, and improvement in housing conditions.
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, Chapter 02: The Dynamics of Disease Transmission
abirb.com/test
Celentano: Gordis Epidemiology, 6th Edition
Test Bank abirb.com/test
MULTIPLE CHOICE
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1. Which term most accurately describes the following definition? “The occurrence in a
community or region of cases of an illness, specific health-related behavior, or other health-
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related events clearly in excess of normal expectancy.” [Porta M, ed. A Dictionary of
Epidemiology. New York: Oxford University Press; 2014.]
abirb.com/test
a. Endemic
b. Epidemic abirb.com/test
c. Pandemic
d. Attack rate
e. Incubation period abirb.com/test
ANS: B
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An epidemic is the occurrence of health-related events in a community or region, in clear
excess of normal expectation. Endemic is not true becauseabirb.com/test
it is defined as the constant
occurrence of a disease, disorder, or noxious infectious agent in a geographic area or
population group. Pandemic is as an epidemic occurring over a
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very wide area, crossing international boundaries, and usually affecting a large number of
people. Attack rate is not true because it is defined as number of people at risk in whom a
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certain illness develops over total number of people at risk. Incubation period is not true
because it is the interval from receipt of infection to the time of onset of clinical illness (the
onset of recognizable symptoms). abirb.com/test
2. What is the most accurate definition of the incubation period (of an infectious disease)?
a. The time of onset of clinical illness or the onset of recognizable symptoms
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b. The interval from receipt of infection to the time of onset of clinical illness (the onset of
recognizable symptoms) abirb.com/test
c. The time of invasion by an infectious agent
d. The time between initiation of infection and first shedding or excretion of the agent
e. The period between exposure and the onset of infectiousnessabirb.com/test
ANS: B
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The incubation period is defined as the interval from receipt of infection to the time of onset
of clinical illness (the onset of recognizable symptoms); inabirb.com/test
other words, the time between the
moment of developing symptoms and the moment of invasion by an infectious agent. “The
time of onset of clinical illness or the onset of recognizable symptoms” is not true as it
corresponds to “time of onset.” “The time of invasion by an infectious agent” is not true as it
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corresponds to “time of infection.” “The time between initiation of infection and first
shedding or excretion of the agent” and “The period between exposure and the onset of
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infectiousness” are not true as they correspond to the latent period. (The latent period is
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