Blood Bank ASCP UPDATED ACTUAL
Exam Questions and CORRECT Answers
Which is the best component to treat a patient with fibrinogen deficiency? - CORRECT
ANSWER - Cryoprecipitated AHF
All of the following are cause for donor deferral EXCEPT? - CORRECT ANSWER - An
individual weighs 115 pounds at the time of donor screening
A 27-year-old female presents to her physician after suffering a spontaneous abortion. Though
rare, which antibody may be the etiological agent? - CORRECT ANSWER - Anti-P
Recombinant Factor IX is indicated for which of the following? - CORRECT ANSWER -
Hemophilia B
Donor red blood cells (RBCs) were collected on July 12th of this year. The RBCs were then
frozen in glycerol on July 17th (5 days later) and stored at -65o C.
What should the expiration date read on the frozen RBC unit? - CORRECT ANSWER -
July 12th; 10 years from collection date
A patient is experiencing prolonged bleeding following a transfusion. The complete blood count
indicates that the patient's platelet count has decreased following the transfusion. What is the
most likely cause of this issue? - CORRECT ANSWER - Posttransfusion purpura
Rh Immune Globulin (RhIG) is used to prevent the active immunization to the D antigen in
women who are Rh negative carrying an Rh positive fetus. One dose of RhIG (equal to 300 µg of
World Health Organization reference material) contains enough anti-D to protect against: -
CORRECT ANSWER - 30 mL of whole blood
Which of the following characteristics of hemolytic disease of the fetus and newborn (HDFN) is
NOT different for ABO and Rh HDFN? - CORRECT ANSWER - Antibody is IgG
, ABO blood groups were discovered by: - CORRECT ANSWER - Landsteiner
When would unexpected positive reactions be encountered during ABO forward typing? -
CORRECT ANSWER - Acquired B antigen
Which of the following choices is the basic technique used to detect unexpected antibodies with
a commercial set of reagent cells? - CORRECT ANSWER - Indirect antiglobulin test
A pregnant female has been injected with Rh Immune Globulin (RhIG) antenatally (28 weeks
gestation) and has a positive antibody screen at delivery. The antibody has been confirmed as
anti-D alone and reacts only weakly (1+ in the indirect antiglobulin test). This antibody may be
the result of: - CORRECT ANSWER - Passive anti-D (RhIg) received at 28 weeks.
Whole blood or red blood cell units will be shipped from the American Red Cross to the
transfusion facility. At what temperature should the units be kept during transportation? -
CORRECT ANSWER - 1-10 °C
Which is in the correct order from the lowest concentration of H antigen to the highest
concentration of H antigen? - CORRECT ANSWER - Bombay, A1B, A1, A2B, B, A2, O
What percentage of glycerol is most commonly used when freezing red blood cell units? -
CORRECT ANSWER - 40%
All of the following serological test results may occur in a patient experiencing a hemolytic
transfusion reaction due to the presence of a clinically significant Rh antibody such as anti-c
EXCEPT: - CORRECT ANSWER - Binding complement.
Antenatal Rh Immune Globulin (RhIG) is typically given at how many weeks gestation? -
CORRECT ANSWER - 28
Exam Questions and CORRECT Answers
Which is the best component to treat a patient with fibrinogen deficiency? - CORRECT
ANSWER - Cryoprecipitated AHF
All of the following are cause for donor deferral EXCEPT? - CORRECT ANSWER - An
individual weighs 115 pounds at the time of donor screening
A 27-year-old female presents to her physician after suffering a spontaneous abortion. Though
rare, which antibody may be the etiological agent? - CORRECT ANSWER - Anti-P
Recombinant Factor IX is indicated for which of the following? - CORRECT ANSWER -
Hemophilia B
Donor red blood cells (RBCs) were collected on July 12th of this year. The RBCs were then
frozen in glycerol on July 17th (5 days later) and stored at -65o C.
What should the expiration date read on the frozen RBC unit? - CORRECT ANSWER -
July 12th; 10 years from collection date
A patient is experiencing prolonged bleeding following a transfusion. The complete blood count
indicates that the patient's platelet count has decreased following the transfusion. What is the
most likely cause of this issue? - CORRECT ANSWER - Posttransfusion purpura
Rh Immune Globulin (RhIG) is used to prevent the active immunization to the D antigen in
women who are Rh negative carrying an Rh positive fetus. One dose of RhIG (equal to 300 µg of
World Health Organization reference material) contains enough anti-D to protect against: -
CORRECT ANSWER - 30 mL of whole blood
Which of the following characteristics of hemolytic disease of the fetus and newborn (HDFN) is
NOT different for ABO and Rh HDFN? - CORRECT ANSWER - Antibody is IgG
, ABO blood groups were discovered by: - CORRECT ANSWER - Landsteiner
When would unexpected positive reactions be encountered during ABO forward typing? -
CORRECT ANSWER - Acquired B antigen
Which of the following choices is the basic technique used to detect unexpected antibodies with
a commercial set of reagent cells? - CORRECT ANSWER - Indirect antiglobulin test
A pregnant female has been injected with Rh Immune Globulin (RhIG) antenatally (28 weeks
gestation) and has a positive antibody screen at delivery. The antibody has been confirmed as
anti-D alone and reacts only weakly (1+ in the indirect antiglobulin test). This antibody may be
the result of: - CORRECT ANSWER - Passive anti-D (RhIg) received at 28 weeks.
Whole blood or red blood cell units will be shipped from the American Red Cross to the
transfusion facility. At what temperature should the units be kept during transportation? -
CORRECT ANSWER - 1-10 °C
Which is in the correct order from the lowest concentration of H antigen to the highest
concentration of H antigen? - CORRECT ANSWER - Bombay, A1B, A1, A2B, B, A2, O
What percentage of glycerol is most commonly used when freezing red blood cell units? -
CORRECT ANSWER - 40%
All of the following serological test results may occur in a patient experiencing a hemolytic
transfusion reaction due to the presence of a clinically significant Rh antibody such as anti-c
EXCEPT: - CORRECT ANSWER - Binding complement.
Antenatal Rh Immune Globulin (RhIG) is typically given at how many weeks gestation? -
CORRECT ANSWER - 28
