PATHOLOGY-CYTOPATHOLOGY NURSE
EXAM QUESTIONS WITH 100% CORRECT
ANSWERS LATEST VERSIONS 2025 GRADED
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The study of cells cytology
Cells are either naturally shed exfoliative cytology
from a surface (often into fluid
e.g. urine) or are gently scraped
from an epithelial surface
(cervical smears)
Cells are forcibly removed from fine needle aspiration biopsy
their natural habitat by aspiration
using a fine needle
Who was originally studying the Papanicolaou in 1928
hormonal effect of the
menstrual cycle on cells
exfoliated from the cervix and
noticed abnormal cells in some
specimens which correlated
with the presence of cervical
cancer?
diagnose malignant and benign neoplasms, screen for precancer
in cervix, hormonal evaluation in female reproductive system,
List a few reasons to perform
screen high risk individuals for cancer (e.g. urine in industrial
cytology?
workers), followup on treated cancer patients, detect
pneumocystis carinii, and viral inclusions.
List three criteria used to large cell size, pleomorphism (variation of cell shape), and loss
distinguish benign from of cohesiveness
malignant cells.
increased N/C ratio, highly irregular nuclear shape, coarsely
List 3 nuclear features which granular and clumped nuclei, more DNA (hyperchromasia),
help in distinguishing benign increased number of nucleoli, irregular and larger nucleoli, and
from malignant cells. mitosis seen in regions other than the basal layer, and abnormal
multi-poled mitotic figures
, Stain that contains nuclear and Papanicolaou stain (PAP smear)
cytoplasmic stains (like H&E),
and Orange G which highlights
the presence of keratin.
A standardized format for The Bethesda System (TBS)
reporting the results of the
cervicovaginal smear is used in
most laboratories today.
Simple, rapid, accurate and cost fine needle aspiration
effective diagnostic technique
with minimal morbidity and
mortality and can be applied to
virtually any part of the body.
Rapidly fixed if smeared on a slide with 95% alcohol or sprayed
How does one process a
with a fixative (unless stained with Romanovsky stain i.e. Diff Quik
cytology specimen?
which used air dried material).
Stored in fridge for 12-24 hours since it slows bacterial growth an
How should a cytology
mucus prevents from degeneration. Or fix in an equal volume of
specimen with a high mucus
50% ethanol or special cytology fixative (Saccomanno fixative -
content be handled?
contains ethylene glycol)
How should a cytology Heparin (3 units per ml of fluid collected) may be added to
specimen with a high protein prevent clotting. Can be refrigerated for 24-48 hours.
content be handled?
How should a cytology Will degenerate in 1-2 hours, should be fixed at time of collection
specimen with a low mucus or in an equal volume of fixative or processed immediately.
protein content be handled?
Name 3 adjuncts to surgical immunohistochemistry, flow cytometry, electron microscopy,
pathology? immunoflourescence, molecular pathology, and cytogenetics.
Name four departments that clinical chemistry, microbiology, hematopathology, and blood
clinical pathology oversees? bank and transfusion medicine
What is the branch of anatomic surgical pathology
pathology that evaluates disease
processes in tissues and organs
removed during surgery?
What stain is used to detect trichrome
collagen and stains the collagen
blue?
What stain is used to stain iron iron stain
dark blue?
What stain is used to stain acid fast
mycobacterium tuberculosis the
chracteristic "red snapper"
appearance?
What stain is used to stain fungi silver stain
and pneumocystis carinii?
What stain is used to stain periodic acid schiff (PAS)
glycogen and fungi?
EXAM QUESTIONS WITH 100% CORRECT
ANSWERS LATEST VERSIONS 2025 GRADED
Save
Students also studied
Flashcard sets Study guides
Certified Dialysis Nurse Test Review... ISA Utility Specialist (Chapters 1-7) 2025 AHIP Final Exa
176 terms Teacher 436 terms Teacher 100 terms
E_Watuka Preview jacklineshee00 Preview cheruiyot_kiplanga
The study of cells cytology
Cells are either naturally shed exfoliative cytology
from a surface (often into fluid
e.g. urine) or are gently scraped
from an epithelial surface
(cervical smears)
Cells are forcibly removed from fine needle aspiration biopsy
their natural habitat by aspiration
using a fine needle
Who was originally studying the Papanicolaou in 1928
hormonal effect of the
menstrual cycle on cells
exfoliated from the cervix and
noticed abnormal cells in some
specimens which correlated
with the presence of cervical
cancer?
diagnose malignant and benign neoplasms, screen for precancer
in cervix, hormonal evaluation in female reproductive system,
List a few reasons to perform
screen high risk individuals for cancer (e.g. urine in industrial
cytology?
workers), followup on treated cancer patients, detect
pneumocystis carinii, and viral inclusions.
List three criteria used to large cell size, pleomorphism (variation of cell shape), and loss
distinguish benign from of cohesiveness
malignant cells.
increased N/C ratio, highly irregular nuclear shape, coarsely
List 3 nuclear features which granular and clumped nuclei, more DNA (hyperchromasia),
help in distinguishing benign increased number of nucleoli, irregular and larger nucleoli, and
from malignant cells. mitosis seen in regions other than the basal layer, and abnormal
multi-poled mitotic figures
, Stain that contains nuclear and Papanicolaou stain (PAP smear)
cytoplasmic stains (like H&E),
and Orange G which highlights
the presence of keratin.
A standardized format for The Bethesda System (TBS)
reporting the results of the
cervicovaginal smear is used in
most laboratories today.
Simple, rapid, accurate and cost fine needle aspiration
effective diagnostic technique
with minimal morbidity and
mortality and can be applied to
virtually any part of the body.
Rapidly fixed if smeared on a slide with 95% alcohol or sprayed
How does one process a
with a fixative (unless stained with Romanovsky stain i.e. Diff Quik
cytology specimen?
which used air dried material).
Stored in fridge for 12-24 hours since it slows bacterial growth an
How should a cytology
mucus prevents from degeneration. Or fix in an equal volume of
specimen with a high mucus
50% ethanol or special cytology fixative (Saccomanno fixative -
content be handled?
contains ethylene glycol)
How should a cytology Heparin (3 units per ml of fluid collected) may be added to
specimen with a high protein prevent clotting. Can be refrigerated for 24-48 hours.
content be handled?
How should a cytology Will degenerate in 1-2 hours, should be fixed at time of collection
specimen with a low mucus or in an equal volume of fixative or processed immediately.
protein content be handled?
Name 3 adjuncts to surgical immunohistochemistry, flow cytometry, electron microscopy,
pathology? immunoflourescence, molecular pathology, and cytogenetics.
Name four departments that clinical chemistry, microbiology, hematopathology, and blood
clinical pathology oversees? bank and transfusion medicine
What is the branch of anatomic surgical pathology
pathology that evaluates disease
processes in tissues and organs
removed during surgery?
What stain is used to detect trichrome
collagen and stains the collagen
blue?
What stain is used to stain iron iron stain
dark blue?
What stain is used to stain acid fast
mycobacterium tuberculosis the
chracteristic "red snapper"
appearance?
What stain is used to stain fungi silver stain
and pneumocystis carinii?
What stain is used to stain periodic acid schiff (PAS)
glycogen and fungi?
