Final Exam: NR565/ NR 565 (Latest 2025/ 2026
Update) Advanced Pharmacology Exam
Review| Questions and Verified Answers –
Chamberlain
1. A .patient .has .a .TSH .of ..28, .a .free .T4 .of .3, .and .a .free .T3 .over .650. .What
.medication .should .she .be .started .on?
Answer: .Methimazole, .PTU, .radioactive .iodine. .These .labs .indicate
.hyperthyroidism. .Treatment .for .thyroid .storm: .K .iodide .or .strong
.iodine .solution .to .suppress .thyroid .release. .Methimazole .to .suppress
.thyroid .synthesis.
2. When .is .it .appropriate .to .increase .insulin .needs?
Answer: .Pregnancy .(after .first .trimester), .stress, .infection, .weight
.loss, .adolescent .growth .spurt. .DECREASE .for .exercise .and .first
.trimester.
3. What .is .the .TDD .of .a .person .that .weighs .70kg?
IF .a .person .is .eating .a .50 .carb .meal, .how .much .insulin .will .be .needed .based .on .the
.TDD .from .the .above .question?
Answer: .42 .TDD .: .21 .basal .21 .bolus .(Wt .in .kg .x .0.6; .50% .long
.acting .and .50% .rapid .acting)
500 .divided .by .(the .TDD) .42 .= .12. .(carb .to .insulin .ratio) .then
.(meal .carbs) .50 .divided .12= .4.1 .units .with .short .acting .insulin
,4. "As .long .as .the .short-acting .insulin .is .drawn .up .first .I .can .mix .my .insulin .glargine
.with .it."
Answer: .Of .the .long-acting .medications, .ONLY .NPH .the
.intermediate .duration .is .suitable .for .mixing .with .the .short .action
.insulins.
5. A .women .who .is .taking .Pioglitazone .states, ."I'm .glad .that .this .medication
.promotes .weight .loss."
Answer: .First .this .medication .promotes .increase .in .LDL .levels,
.which .increases .cardiovascular .risk. .Also, .she's .a .female .so .speak
.about .exercise .and .weight .bearing .exercise .d/t .possible .increased
.risk .for .fractures.
6. Glucocorticoid .MOA
Answer: .Most .effective .in .long-term .control .of .airway .inflammation
7. Cromolyn .MOA
Answer: .Used .as .prophylaxis .for .mild .to .moderate .asthma
8. Monoclonal .Antibodies .MOA
Answer: .Used .for .allergy-related .asthma .and .Eosinophilic .asthma.
.Omalizumab .for .allergy .related .and .Ben .ralizumab, .mepliz, .and
.resliz .are .for .eosinophilic
9. Leukotriene .MOA
, Answer: .Second-line .therapy .to .reduce .inflammation
.and .bronchoconstriction
10. B2 .adrenergic .agonists .MOA
Answer: .Can .be .used .PRN, .for .EIB, .COPD .exacerbations,
.and .maintenance .therapy
11. methylxanthines .MOA
Answer: .Maintenance .therapy .for .chronic .stable .asthma .(theophylline).
P. .570. .Use .ONLY .if .B2 .or .anticholinergics .are .not .appropriate.
12. anticholinergic .MOA
Answer: .Approved .for .bronchospasm .related .to .COPD
13. •What .are .some .risk .factors .of .fatal .asthma .attacks?
Answer: .Uncontrolled, .hospitalized .recently, .triggers,
14. •Roflumilast .(select .all .that .apply)
1. Reduces .inflammation
2. Not .intended .during .pregnancy
3. Approved .for .asthma
4. First-line .drug .for .COPD
Answer: .Reduces .inflammation, .not .intended .for .pregnancy,
.approved .only .for .COPD, .Second-line .drug .for .COPD
, Uses .for .exacerbations .prophylaxis .in .pts .with .severe .COPD .with
.a .primary .chronic .bronchitis .component.
15. What .pt .education .can .you .provide .a .patient .for .ICS .use?
Answer: .Rinse .d/t .oropharyngeal .candidiasis .and
.dysphonia .(hoarseness, .difficulty .speaking).
16. What .patient .teaching .can .a .provider .give .when .prescribing .a .PPI?
Answer: .Hypomagnesia .symptoms: .muscle .cramps, .tremors, .cramps,
.and .palpitations. .Check .Mg .levels .periodically .especially .in .the
.elderly. .Get .enough .calcium .and .VIT .D. .call .if .having .diarrhea
.(Cdiff)
17. What .patient .teaching .can .a .provider .give .when .prescribing .an .H2RA?
Answer: .Report .lethargy, .solmnolance, .restlessness, .confusion .or
.hallucinations. .(CNS .effects). .Teach .about .possible .reduced .libido,
.impotence, .gynecomastia, .pneumonia. .P.594 .Cimetidine .interacts
.with .CYP .system .so .check .with .pt .if .they .are .taking .warfarin,
.phenytoin, .theophylline, .lidocaine.
18. A .patient .presents .with .a .complaint .of .reflux .and .constipation. .He .states .that .he
.drinks .enough .water, .and .admits .he .has .gained .30lbs. .He .also .states .that .he .has
.been .having ."reflux" .type .symptoms. .What .are .your .next .steps .for .education?
Answer: .Educate .that .weight .gain .can .promote .reflux .symptoms,
.ask .about .any .otc .use .such .as .antacids .which .may .cause
.constipation.
19. zollinger-Ellison .syndrome .is .due .to .a . producing .tumor. .Treatment .is .long-
term .therapy .of .what .medication .class?
Update) Advanced Pharmacology Exam
Review| Questions and Verified Answers –
Chamberlain
1. A .patient .has .a .TSH .of ..28, .a .free .T4 .of .3, .and .a .free .T3 .over .650. .What
.medication .should .she .be .started .on?
Answer: .Methimazole, .PTU, .radioactive .iodine. .These .labs .indicate
.hyperthyroidism. .Treatment .for .thyroid .storm: .K .iodide .or .strong
.iodine .solution .to .suppress .thyroid .release. .Methimazole .to .suppress
.thyroid .synthesis.
2. When .is .it .appropriate .to .increase .insulin .needs?
Answer: .Pregnancy .(after .first .trimester), .stress, .infection, .weight
.loss, .adolescent .growth .spurt. .DECREASE .for .exercise .and .first
.trimester.
3. What .is .the .TDD .of .a .person .that .weighs .70kg?
IF .a .person .is .eating .a .50 .carb .meal, .how .much .insulin .will .be .needed .based .on .the
.TDD .from .the .above .question?
Answer: .42 .TDD .: .21 .basal .21 .bolus .(Wt .in .kg .x .0.6; .50% .long
.acting .and .50% .rapid .acting)
500 .divided .by .(the .TDD) .42 .= .12. .(carb .to .insulin .ratio) .then
.(meal .carbs) .50 .divided .12= .4.1 .units .with .short .acting .insulin
,4. "As .long .as .the .short-acting .insulin .is .drawn .up .first .I .can .mix .my .insulin .glargine
.with .it."
Answer: .Of .the .long-acting .medications, .ONLY .NPH .the
.intermediate .duration .is .suitable .for .mixing .with .the .short .action
.insulins.
5. A .women .who .is .taking .Pioglitazone .states, ."I'm .glad .that .this .medication
.promotes .weight .loss."
Answer: .First .this .medication .promotes .increase .in .LDL .levels,
.which .increases .cardiovascular .risk. .Also, .she's .a .female .so .speak
.about .exercise .and .weight .bearing .exercise .d/t .possible .increased
.risk .for .fractures.
6. Glucocorticoid .MOA
Answer: .Most .effective .in .long-term .control .of .airway .inflammation
7. Cromolyn .MOA
Answer: .Used .as .prophylaxis .for .mild .to .moderate .asthma
8. Monoclonal .Antibodies .MOA
Answer: .Used .for .allergy-related .asthma .and .Eosinophilic .asthma.
.Omalizumab .for .allergy .related .and .Ben .ralizumab, .mepliz, .and
.resliz .are .for .eosinophilic
9. Leukotriene .MOA
, Answer: .Second-line .therapy .to .reduce .inflammation
.and .bronchoconstriction
10. B2 .adrenergic .agonists .MOA
Answer: .Can .be .used .PRN, .for .EIB, .COPD .exacerbations,
.and .maintenance .therapy
11. methylxanthines .MOA
Answer: .Maintenance .therapy .for .chronic .stable .asthma .(theophylline).
P. .570. .Use .ONLY .if .B2 .or .anticholinergics .are .not .appropriate.
12. anticholinergic .MOA
Answer: .Approved .for .bronchospasm .related .to .COPD
13. •What .are .some .risk .factors .of .fatal .asthma .attacks?
Answer: .Uncontrolled, .hospitalized .recently, .triggers,
14. •Roflumilast .(select .all .that .apply)
1. Reduces .inflammation
2. Not .intended .during .pregnancy
3. Approved .for .asthma
4. First-line .drug .for .COPD
Answer: .Reduces .inflammation, .not .intended .for .pregnancy,
.approved .only .for .COPD, .Second-line .drug .for .COPD
, Uses .for .exacerbations .prophylaxis .in .pts .with .severe .COPD .with
.a .primary .chronic .bronchitis .component.
15. What .pt .education .can .you .provide .a .patient .for .ICS .use?
Answer: .Rinse .d/t .oropharyngeal .candidiasis .and
.dysphonia .(hoarseness, .difficulty .speaking).
16. What .patient .teaching .can .a .provider .give .when .prescribing .a .PPI?
Answer: .Hypomagnesia .symptoms: .muscle .cramps, .tremors, .cramps,
.and .palpitations. .Check .Mg .levels .periodically .especially .in .the
.elderly. .Get .enough .calcium .and .VIT .D. .call .if .having .diarrhea
.(Cdiff)
17. What .patient .teaching .can .a .provider .give .when .prescribing .an .H2RA?
Answer: .Report .lethargy, .solmnolance, .restlessness, .confusion .or
.hallucinations. .(CNS .effects). .Teach .about .possible .reduced .libido,
.impotence, .gynecomastia, .pneumonia. .P.594 .Cimetidine .interacts
.with .CYP .system .so .check .with .pt .if .they .are .taking .warfarin,
.phenytoin, .theophylline, .lidocaine.
18. A .patient .presents .with .a .complaint .of .reflux .and .constipation. .He .states .that .he
.drinks .enough .water, .and .admits .he .has .gained .30lbs. .He .also .states .that .he .has
.been .having ."reflux" .type .symptoms. .What .are .your .next .steps .for .education?
Answer: .Educate .that .weight .gain .can .promote .reflux .symptoms,
.ask .about .any .otc .use .such .as .antacids .which .may .cause
.constipation.
19. zollinger-Ellison .syndrome .is .due .to .a . producing .tumor. .Treatment .is .long-
term .therapy .of .what .medication .class?
