Double-stranded regions of RNA: ANS Can form between two self-complementary regions of the same
single strand of RNA
Which of the following is a palindromic sequence? ANS GGATCC CCTAGG
The compound that consists of ribose linked by an N-glycosidic bond to N-9 of adenine is: ANS
Adenosine
In the Watson-Crick model of DNA structure (now called B-form DNA): ANS The bases occupy the
interior of the helix
Which of the following is not true of all naturally occurring DNA? ANS The ratio A+T/G+C is constant
for all natural DNAs
The phosphodiester bonds that link adjacent nucleotides in both RNA and DNA: ANS Join the 3' hydroxyl
of one nucleotide to the 5' hydroxyl of the next
In the Watson-Crick model of DNA structure: ANS The distance between two adjacent bases in one strand
is about 3.4 Å
The difference between a ribonucleotide and a deoxyribonucleotide is: ANS A deoxyribonucleotide has an
—H instead of an —OH at C-2
Triple-helical DNA structures can result from Hoogsteen (non Watson-Crick) interactions. These interactions
are
primarily: ANS Hydrogen bonds involving the bases
The phosphodiester bonds that link adjacent nucleotides in both RNA and DNA: ANS Join the 3' hydroxyl
of one nucleotide to the 5' hydroxyl of the next
The "energy carrier" ATP is an example of a(n): ANS Ribonucleosidetriphosphate
, In the Watson-Crick model for the DNA double helix (B form), the A-T and G-C base pairs share which one of
the
following properties? ANS The distance between the two glycosidic (base-sugar) bonds is the same in both
base pairs, within a few
tenths of an angstro
Which one of the following is true of the pentoses found in nucleic acids? ANS The pentoses are always in
the beta-furanose forms
A major component of RNA but not of DNA is: ANS Uracil
For the oligoribonucleotide pACGUAC: ANS The nucleotide at the 5' end has a phosphate on its 5'
hydroxyl
The experiment of Avery, MacLeod, and McCarty in which nonvirulent bacteria were made virulent by
transformation was significant because it showed that: ANS Genes are composed of DNA only
When double-stranded DNA is heated at neutral pH, which change does not occur? ANS The covalent N-
glycosidic bond between the base and the pentose breaks
B-form DNA in vivo is a ________-handed helix, _____ Å in diameter, with a rise of ____ Å per base pair.
ANS Right; 20; 3.4
In comparison with DNA-DNA double helices, the stability of DNA-RNA and RNA-RNA helices is: ANS
RNA-RNA > DNA-RNA > DNA-DNA
In double-stranded DNA: ANS The two strands have complementary sequences
n nucleotides and nucleic acids, syn and anti conformations relate to: ANS Rotation around the sugar-base
bond
The phosphodiester bond that joins adjacent nucleotides in DNA: ANS Associates ionically with metal
ions, polyamines, and proteins