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PHARMACOLOGY STEP 3 (570
QUESTIONS AND ANSWERS) 2024/2025
UPDATED LATEST GRADED A+.
What knee ligament is classically injured in a dashboard injury? - Precise
answer PCL
What is vulvodynia and how do we treat it? - Precise answer Chronic (>3
months) raw and burning vulvar pain that occurs in the absence of a
specific disorder. Treat with CBT
Describe how we do a trial of discontinuation of BP meds? - Precise
answer Reduce dose over 1-2 months and monitor BP response
How do we manage an eye injury with blood collection in anterior
chamber? - Precise answer Admit to hospital for monitoring for intraocular
pressure in case of rebleed
When should chest pain be worked up with it an echo versus a stress test?
- Precise answer Work up chest pain with an echo when you're suspicious
for heart failure i.e. signs of fluid overload like lower extremity edema and
pulmonary crackles
work up chest pain with a stress test in absence of signs of heart failure,
when you're more concerned about coronary artery disease
How does radiation therapy affect the architecture of the heart? - Precise
answer Radiation therapy causes diffuse fibrosis in the interstitium of the
myocardium along with progressive fibrosis of the pericardial layers, cells in
the conduction system, and the cuffs and/or leaflets of the valves. It can
also cause injury to the intimal layer, with arterial narrowing typically
involving the Ostia of the coronary vessels
What are some mechanisms of reducing risk of development of a topic
dermatitis in a child with a positive family history? - Precise answer Early
,(
exposure to non-pathogenic microorganisms such as childhood exposure
to daycare, household pets, and farm animals, as well as breast-feeding
and emollient application to provide a protective barrier layer to the skin
What is Parinaud syndrome? - Precise answer Loss of pupillary reaction,
vertical gaze paralysis, The loss of optokinetic nystagmus, and ataxia 2/2
pineal tumor
What is the most effective pharmacologic therapy for reducing the risk of
postoperative a fib? - Precise answer Beta blockers
actinic keratosis is precancer for what type of cancer - Precise answer
Squamous cell
Persistent diarrhea at a postop appointment after cholecystectomy is likely
what ? - Precise answer Bile-salt induced - treat with cholestyramine
How do we treat neonatal polycythemia acutely? - Precise answer Fluids,
correct metabolic derangements, partial exchange transfusion if failure to
improve with conservative mgmt
How do you calculate likelihood ratio? - Precise answer sensitivity/(1-
specificity)
How do we manage asymptotic gallstones in pregnancy? - Precise answer
Reassurance and follow up - no need for elective cholecystectomy because
gallstones that arise in pregnancy often go away after delivery
How long must we wait to administer live vaccines in a pt recently treated
with IVIG? - Precise answer 11 months
What type of relationship suggests causality? - Precise answer Dose
response
How do we treat a symptomatic BV? - Precise answer Flagyl
What infectious agent can cause papules with central umbilication in and
HIV pt? How do we make the diagnosis? - Precise answer Cryptococcus
lesion biopsy
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At what BhCG level should a gestational sac be seen? - Precise answer
3500
What study designs identifies a disease and looks back for exposure? -
Precise answer Case control
Diagnosis in a pt with palpable purpura, elevated RF, low complement ? -
Precise answer Mixed cryoglobulinemia
At what CD4 count are pts susceptible to pneumocystis? - Precise answer
200
What causes febrile dilated cardiomyopathy with high LVEF versus low? -
Precise answer High is thyroid storm and low is viral
What lab value do we target to monitor adequate tx of thyroid cancer? -
Precise answer TSH
What is the first test done to assess for osteoblastic lesions in a cancer
patient? - Precise answer Radionuclide bone scan
How do you calculate corrected calcium? - Precise answer [(4-
Albumin)*0.8] + Serum Calcium
tx for acute dystonia - Precise answer benztropine or diphenhydramine
How do we treat allergic bronchopulmonary aspergillosis? - Precise
answer Oral steroids and itraconazole/voriconazole
What might be a cause of severe abdominal pain after MI? - Precise
answer Acute mesenteric ischemia
What is the timing of symptoms of dumping syndrome? - Precise answer
After meals
What nonsurgical options are there for throat cancer? - Precise answer
Radiation and chemotherapy
, (
What preoperative consideration should be made in pts with DM about to
receive cardiac catheterization for CAD? - Precise answer Discontinue
metformin, Not aspirin
What EKG changes are associated with tumor lysis syndrome? - Precise
answer Hyperkalemia and myocardial calcium phosphate deposition can
cause widening of QRS
What is next step in a pt on abx for pyelo with obstructing nephrolithiasis? -
Precise answer PCN or ureteral stent for decompression
What are the three CHD risk equivalents? - Precise answer CKD,
noncoronary atherosclerotic disease (peripheral artery, carotid, abdominal
aortic aneurysm), Diabetes Mellitus
Diagnosis in a 50 yo pt with muscle aches in shoulders and pelvic girdle,
elevated ESR? - Precise answer Polymyalgia rheumatica
tx for malignant otitis externa - Precise answer
What is the main physical exam finding of bronchospasm postoperatively? -
Precise answer Wheezing
How long is anticoagulation necessary after a DVT as a result of a
reversible or time limited risk factor ? - Precise answer 3-6 months
What is scromboid poisoning? - Precise answer Flushing, throbbing
headache, palpitations, abdominal cramps, oral burning, diarrhea after
consuming improperly stored fish
What is diagnosis in a pt with a painful vesicular rash, fever, LAD,
associated with atopic dermatitis? - Precise answer Eczema herpeticum
What supplements should be avoided taking at the same time as
levothyroxine? - Precise answer Calcium and iron (take at different time in
day)
What value does calculating the inverse of relative risk give you? - Precise
answer Relative risk of denominator to numerator instead of numerator to
denominator
PHARMACOLOGY STEP 3 (570
QUESTIONS AND ANSWERS) 2024/2025
UPDATED LATEST GRADED A+.
What knee ligament is classically injured in a dashboard injury? - Precise
answer PCL
What is vulvodynia and how do we treat it? - Precise answer Chronic (>3
months) raw and burning vulvar pain that occurs in the absence of a
specific disorder. Treat with CBT
Describe how we do a trial of discontinuation of BP meds? - Precise
answer Reduce dose over 1-2 months and monitor BP response
How do we manage an eye injury with blood collection in anterior
chamber? - Precise answer Admit to hospital for monitoring for intraocular
pressure in case of rebleed
When should chest pain be worked up with it an echo versus a stress test?
- Precise answer Work up chest pain with an echo when you're suspicious
for heart failure i.e. signs of fluid overload like lower extremity edema and
pulmonary crackles
work up chest pain with a stress test in absence of signs of heart failure,
when you're more concerned about coronary artery disease
How does radiation therapy affect the architecture of the heart? - Precise
answer Radiation therapy causes diffuse fibrosis in the interstitium of the
myocardium along with progressive fibrosis of the pericardial layers, cells in
the conduction system, and the cuffs and/or leaflets of the valves. It can
also cause injury to the intimal layer, with arterial narrowing typically
involving the Ostia of the coronary vessels
What are some mechanisms of reducing risk of development of a topic
dermatitis in a child with a positive family history? - Precise answer Early
,(
exposure to non-pathogenic microorganisms such as childhood exposure
to daycare, household pets, and farm animals, as well as breast-feeding
and emollient application to provide a protective barrier layer to the skin
What is Parinaud syndrome? - Precise answer Loss of pupillary reaction,
vertical gaze paralysis, The loss of optokinetic nystagmus, and ataxia 2/2
pineal tumor
What is the most effective pharmacologic therapy for reducing the risk of
postoperative a fib? - Precise answer Beta blockers
actinic keratosis is precancer for what type of cancer - Precise answer
Squamous cell
Persistent diarrhea at a postop appointment after cholecystectomy is likely
what ? - Precise answer Bile-salt induced - treat with cholestyramine
How do we treat neonatal polycythemia acutely? - Precise answer Fluids,
correct metabolic derangements, partial exchange transfusion if failure to
improve with conservative mgmt
How do you calculate likelihood ratio? - Precise answer sensitivity/(1-
specificity)
How do we manage asymptotic gallstones in pregnancy? - Precise answer
Reassurance and follow up - no need for elective cholecystectomy because
gallstones that arise in pregnancy often go away after delivery
How long must we wait to administer live vaccines in a pt recently treated
with IVIG? - Precise answer 11 months
What type of relationship suggests causality? - Precise answer Dose
response
How do we treat a symptomatic BV? - Precise answer Flagyl
What infectious agent can cause papules with central umbilication in and
HIV pt? How do we make the diagnosis? - Precise answer Cryptococcus
lesion biopsy
,(
At what BhCG level should a gestational sac be seen? - Precise answer
3500
What study designs identifies a disease and looks back for exposure? -
Precise answer Case control
Diagnosis in a pt with palpable purpura, elevated RF, low complement ? -
Precise answer Mixed cryoglobulinemia
At what CD4 count are pts susceptible to pneumocystis? - Precise answer
200
What causes febrile dilated cardiomyopathy with high LVEF versus low? -
Precise answer High is thyroid storm and low is viral
What lab value do we target to monitor adequate tx of thyroid cancer? -
Precise answer TSH
What is the first test done to assess for osteoblastic lesions in a cancer
patient? - Precise answer Radionuclide bone scan
How do you calculate corrected calcium? - Precise answer [(4-
Albumin)*0.8] + Serum Calcium
tx for acute dystonia - Precise answer benztropine or diphenhydramine
How do we treat allergic bronchopulmonary aspergillosis? - Precise
answer Oral steroids and itraconazole/voriconazole
What might be a cause of severe abdominal pain after MI? - Precise
answer Acute mesenteric ischemia
What is the timing of symptoms of dumping syndrome? - Precise answer
After meals
What nonsurgical options are there for throat cancer? - Precise answer
Radiation and chemotherapy
, (
What preoperative consideration should be made in pts with DM about to
receive cardiac catheterization for CAD? - Precise answer Discontinue
metformin, Not aspirin
What EKG changes are associated with tumor lysis syndrome? - Precise
answer Hyperkalemia and myocardial calcium phosphate deposition can
cause widening of QRS
What is next step in a pt on abx for pyelo with obstructing nephrolithiasis? -
Precise answer PCN or ureteral stent for decompression
What are the three CHD risk equivalents? - Precise answer CKD,
noncoronary atherosclerotic disease (peripheral artery, carotid, abdominal
aortic aneurysm), Diabetes Mellitus
Diagnosis in a 50 yo pt with muscle aches in shoulders and pelvic girdle,
elevated ESR? - Precise answer Polymyalgia rheumatica
tx for malignant otitis externa - Precise answer
What is the main physical exam finding of bronchospasm postoperatively? -
Precise answer Wheezing
How long is anticoagulation necessary after a DVT as a result of a
reversible or time limited risk factor ? - Precise answer 3-6 months
What is scromboid poisoning? - Precise answer Flushing, throbbing
headache, palpitations, abdominal cramps, oral burning, diarrhea after
consuming improperly stored fish
What is diagnosis in a pt with a painful vesicular rash, fever, LAD,
associated with atopic dermatitis? - Precise answer Eczema herpeticum
What supplements should be avoided taking at the same time as
levothyroxine? - Precise answer Calcium and iron (take at different time in
day)
What value does calculating the inverse of relative risk give you? - Precise
answer Relative risk of denominator to numerator instead of numerator to
denominator
