GNRS 582A Final exam with correct answers
3 Na+ out, 2 K+ in - CORRECT ANSWERS ✔✔normal function of Na/K
pump
1. decrease ATP production
2. Failure of Na/K pump
3. ROS
4. Ca2+ entry
5. Lysis - CORRECT ANSWERS ✔✔common biochemical themes in cellular
injury
failure of Na/K pump - CORRECT ANSWERS ✔✔what causes ca2+ influx
reperfusion injury - CORRECT ANSWERS ✔✔causes excess ROS and Ca2+
overload
leading to cell death acitvation
transduction, transmission, perception, modulation - CORRECT ANSWERS
✔✔process of nociception
peripheral neuropathic pain - CORRECT ANSWERS ✔✔nerve becomes
excitable causing numbing, tingling, burning and aching pain
, chronic pain - CORRECT ANSWERS ✔✔last 3-6 months
no protective purpose
leads to physiological adaptation --> depression, eating/sleeping difficulty
inflammatory response - CORRECT ANSWERS ✔✔second line of defense:
innate, natural, nonspecific
fever - CORRECT ANSWERS ✔✔kills microorganisms
affects their growth and replication
decreases iron, copper, and zinc
enhances phagocytosis
complement system - CORRECT ANSWERS ✔✔collaboration and direct
destruction
end result: damage to bacterium
clotting system - CORRECT ANSWERS ✔✔coagulation, capture, repair
end result: blood clot, leukocyte, neutrophil migration, increased permeability
in blood vessel
kinin system - CORRECT ANSWERS ✔✔pain and permeability
end result: stimulates nerve endings, pain
adaptive immunity - CORRECT ANSWERS ✔✔third line of defense
3 Na+ out, 2 K+ in - CORRECT ANSWERS ✔✔normal function of Na/K
pump
1. decrease ATP production
2. Failure of Na/K pump
3. ROS
4. Ca2+ entry
5. Lysis - CORRECT ANSWERS ✔✔common biochemical themes in cellular
injury
failure of Na/K pump - CORRECT ANSWERS ✔✔what causes ca2+ influx
reperfusion injury - CORRECT ANSWERS ✔✔causes excess ROS and Ca2+
overload
leading to cell death acitvation
transduction, transmission, perception, modulation - CORRECT ANSWERS
✔✔process of nociception
peripheral neuropathic pain - CORRECT ANSWERS ✔✔nerve becomes
excitable causing numbing, tingling, burning and aching pain
, chronic pain - CORRECT ANSWERS ✔✔last 3-6 months
no protective purpose
leads to physiological adaptation --> depression, eating/sleeping difficulty
inflammatory response - CORRECT ANSWERS ✔✔second line of defense:
innate, natural, nonspecific
fever - CORRECT ANSWERS ✔✔kills microorganisms
affects their growth and replication
decreases iron, copper, and zinc
enhances phagocytosis
complement system - CORRECT ANSWERS ✔✔collaboration and direct
destruction
end result: damage to bacterium
clotting system - CORRECT ANSWERS ✔✔coagulation, capture, repair
end result: blood clot, leukocyte, neutrophil migration, increased permeability
in blood vessel
kinin system - CORRECT ANSWERS ✔✔pain and permeability
end result: stimulates nerve endings, pain
adaptive immunity - CORRECT ANSWERS ✔✔third line of defense