NR546 Week 2: test your knowledge quiz

NR546 Week 2: test your knowledge quiz


 Pharmacokinetics...Answer is... the study of what happens to a drug from the time of
administration until the parent drug and all metabolites leave the body



 Pharmacokinetics concepts...Answer is... absorption
 distribution
 metabolism
 excretion



 Flockhart Table...Answer is... drug interactions that are mediated by cytochrome P450 enzymes



 comprehensive list of drugs and the interactions related to the cytochrome P450 system



 client factors that impact the effect of psychotropic medications...Answer is... -age
 -diet
 -smoking status
 -other prescribed medications
 -over-the-counter medications



 *all impact drug metabolism



 Neurotransmitters...Answer is... chemicals released by neurons to send communication across
synaptic clefts to other neurons
 -impact human emotion and behavior



 Many psychiatric disorders and client symptoms occur from an excess, deficiency, or imbalance
of _________...Answer is... neurotransmitters



 Neurotransmission:...Answer is... the chemical transmission of information between neurons
and their target cells

,  -the chemicals, or neurotransmitters, are released from their transport vesicles to bind with
receptor sites to perform their duties, which are excitatory or inhibitory
 -neurotransmitter then either returned and stored for future use (reuptake) or inactivated and
dissolved by enzymes



 Excitatory neurotransmitters:...Answer is... increase the likelihood that the neuron will fire an
action potential



 inhibitory neurotransmitters:...Answer is... decrease the likelihood that a neuron will fire an
action



 neurotransmitters that most impact mental health can be classified into four major
categories:...Answer is... cholinergics
 -acetylcholine



 monoamines
 -norepinephrine, dopamine, serotonin, histamine



 amino acids
 -gamma- amino-butyric acid and glutamate



 neuropeptides



 Inhibitors: VISA CKGQ...Answer is... Valproate
 Isoniazid
 Sulfonamides
 Amiodarone
 Chloramphenicol
 Ketoconazole
 Grapefruit Juice
 Quinidine



 -decrease medication metabolism