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What do you do if a Check renal function
patient on lithium
has dark brown
urine?
What do you do if a Check ANC level to assess for
patient presents agranulocytosis
with fever while on
Clozaril?
What can cause Antidepressants, St. John's Wort, Same-E,
serotonin Kava Kava, and Tryptophan
syndrome?
What labs are Elevated WBC (over 11,000) and elevated
indicative of NMS? CPK
muscle rigidity, hyperthermia, tachycardia,
S/S of NMS abnormal bp, sweating, altered mental
status, cherry colored urine
, What should you do Check for rhabdo with CPK
if a patient presents
with cherry colored
urine?
hyperreflexia, muscle spasms, myoclonus
s/s of serotonin
(involuntary muscle jerk), fever,
syndrome
tachycardia, HTN, shits and shivers
What two bromocriptine (Parlodel)- D2 agonist
medications to give dantrolene- muscle relaxer
with NMS?
What medication to cyproheptadine (Periactin)- 5HT-2A
give during SS? receptor antagonist
What is the onset Slow onset (1-2 weeks after changing or
and typical length starting therapy) and resolves within 9-14
of NMS? days
What is the onset of Within 24 hours of starting/changing
SS? medication and resolves within a few days
How do you NMS has a slower onset while acute
distinguish between dystonia occurs within hours
NMS and acute
dystonia?
What happens with Increased risk of lithium toxicity (gout
lithium and meds, ibuprophen, naproxen, etc.)
NSAIDs?
What happens with Increased risk of lithium toxicity related to
lithium and ACE the increased urination from the ACE
inhibitors? inhibitors