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MB (ASCP) EXAM 2025 BRAND NEW
ACTUAL EXAM WITH ANSWERS.
1. What gene is affected in Follicular Lymphoma? - correct
answer-BCL2
2. What genes lose function in Acute Promyelocyctic Lymphoma?
- correct answer-RARA(15) and PML (17)
3. What gene shows increased expression in Mantle Cell
Lymphoma? - correct answer-CCND1
4. What triplet repeat is an indicator of Huntington Disease? -
correct answer-CAG
5. Which gene is defective in hemoglinopathy? - correct answer-
MTHFR
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6. Mutations in what gene are the most common oncogene
mutation in human cancers? - correct answer-K-ras
7. A Robertsonian translocation may be associated with which
genetic disorder? - correct answer-Down Syndrome
8. Which locus is used to identify the gender of the individual from
whom a DNA sample is obtained? - correct answer-Amelogenin
9. Pyrimidines - correct answer-Cytosine and Thymine
10. Purines - correct answer-Adenine and Guanine
11. Which RNA polymerase synthesizes rRNA? - correct
answer-RNA pol I
12. Which RNA polymerase synthesizes tRNA? - correct
answer-RNA pol iii
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13. Proteins that bind to DNA to control gene expression are
called: - correct answer-Trans factors
14. The binding sites on DNA for proteins that control gene
expression are called: - correct answer-Cis factors
15. What sequence structures in DNA (usually found 5' to
structural genes) are frequent sites of DNA methylation? -
correct answer-CpG islands
16. CGH arrays are performed on: - correct answer-DNA
17. Expression arrays are performed on: - correct answer-RNA
18. Detect deletions and amplifications of chromosomal regions
- correct answer-CGH arrays
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19. Detect changes in the RNA levels of specific genes - correct
answer-Expression arrays
20. What occurs when primers hybridize to each other at the 3'
ends? - correct answer-primer dimers
21. MALDI methods separate ions by: - correct answer-Mass
and charge
22. What causes stutter anomaly (small peaks in engraftment)? -
correct answer-strand slippage
23. What is the minimum amount of loci with matched alleles to
be considered for legal identification? - correct answer-8
24. Predominant form of DNA - correct answer-Right-handed B
MB (ASCP) EXAM 2025 BRAND NEW
ACTUAL EXAM WITH ANSWERS.
1. What gene is affected in Follicular Lymphoma? - correct
answer-BCL2
2. What genes lose function in Acute Promyelocyctic Lymphoma?
- correct answer-RARA(15) and PML (17)
3. What gene shows increased expression in Mantle Cell
Lymphoma? - correct answer-CCND1
4. What triplet repeat is an indicator of Huntington Disease? -
correct answer-CAG
5. Which gene is defective in hemoglinopathy? - correct answer-
MTHFR
, Page | 2
6. Mutations in what gene are the most common oncogene
mutation in human cancers? - correct answer-K-ras
7. A Robertsonian translocation may be associated with which
genetic disorder? - correct answer-Down Syndrome
8. Which locus is used to identify the gender of the individual from
whom a DNA sample is obtained? - correct answer-Amelogenin
9. Pyrimidines - correct answer-Cytosine and Thymine
10. Purines - correct answer-Adenine and Guanine
11. Which RNA polymerase synthesizes rRNA? - correct
answer-RNA pol I
12. Which RNA polymerase synthesizes tRNA? - correct
answer-RNA pol iii
, Page | 3
13. Proteins that bind to DNA to control gene expression are
called: - correct answer-Trans factors
14. The binding sites on DNA for proteins that control gene
expression are called: - correct answer-Cis factors
15. What sequence structures in DNA (usually found 5' to
structural genes) are frequent sites of DNA methylation? -
correct answer-CpG islands
16. CGH arrays are performed on: - correct answer-DNA
17. Expression arrays are performed on: - correct answer-RNA
18. Detect deletions and amplifications of chromosomal regions
- correct answer-CGH arrays
, Page | 4
19. Detect changes in the RNA levels of specific genes - correct
answer-Expression arrays
20. What occurs when primers hybridize to each other at the 3'
ends? - correct answer-primer dimers
21. MALDI methods separate ions by: - correct answer-Mass
and charge
22. What causes stutter anomaly (small peaks in engraftment)? -
correct answer-strand slippage
23. What is the minimum amount of loci with matched alleles to
be considered for legal identification? - correct answer-8
24. Predominant form of DNA - correct answer-Right-handed B
