Page 1 of 247
f f f
,Page 2 of 247
f f f
, Test Bank f
to accompany
f
Psychopharmacology, fourth Edition f f
Meyer • Quenzer
f f
Chapter 1: Principles of Pharmacology f f f f
Multiple Choice f
1. refer(s) to specific molecular changes that occur when a drug binds to a f f f f f f f f f f f f
particular target site or receptor, while
f f are the resulting widespread alterations
f f f f f f f f
in function.
f f
a. Drug action; therapeutic effects
f f f
b. Side effects; drug effects
f f f
c. Therapeutic effects; side effects f f f
d. Drug action; drug effects
f f f
Answer: d f
Textbook Reference: Pharmacology: The Science of Drug Action
f f f f f f f
2. After drug administration has occurred, the amount of drug in the blood that is free to
f f f f f f f f f f f f f f f
bind at specific target sites is referred to as
f f f f f f f f f
a. the therapeutic dose.
f f
b. first-pass effects. f
c. bioavailability.
d. ED50.
Answer: c f
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
f f f f f f
3. The specific molecular changes that occur when a drug binds to a particular target site or
f f f f f f f f f f f f f f f
receptor are referred to as
f f f f f
a. drug effects. f
b. drug action. f
c. side effects.f
d. placebo effects. f
Answer: b f
Textbook Reference: Pharmacology: The Science of Drug Action
f f f f f f f
4. Which of the following is not a possible explanation for placebo effects?
f f f f f f f f f f f
a. Pavlovian conditioning f
b. Genetic variation f
c. Drug competition f
d. Expectation of outcome f f
Answer: c f
Textbook Reference: Pharmacology: The Science of Drug Action
f f f f f f f
Page 3 of 247
f f f
, 5. The administration of oxytocin has been proposed as a treatment for autism. f f f f f f f f f f
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c f
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
f f f f f f
6. Which factor does not affect the pharmacokinetics of a drug?
f f f f f f f f f
a. Route of administration
f f
b. Lipid solubility
f
c. Depot binding f
d. Drug actionf
Answer: d f
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
f f f f f f
7. First-pass metabolism occurs when drugs are taken
f f f f f f
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a f
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
f f f f f f
8. The area postrema is one area in the brain where the
f f is not complete. f f f f f f f f f f
a. cerebrospinal fluid f
b. blood–brain barrier f
c. choroid plexus f
d. phospholipid membrane f
Answer: b f
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
f f f f f f
9. First-pass metabolism occurs with orally administered drugs because
f f f f f f f
a. their absorption is slowed by food.
f f f f f
b. drugs absorbed into the bloodstream from the stomach go to the liver on the way to
f f f f f f f f f f f f f f f
general circulation.
f f
c. drugs must first survive the acidic environment of the stomach.
f f f f f f f f f
d. salivary enzymes in the mouth begin the process of metabolism.
f f f f f f f f f
Answer: b f
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
f f f f f f
10. Toxic substances in the blood trigger a vomiting response by activating the
f f f f f f f f f f f
a. blood–brain barrier. f
b. choroid plexus. f
c. area postrema.
f
d. median eminence. f
Page 4 of 247
f f f
f f f
,Page 2 of 247
f f f
, Test Bank f
to accompany
f
Psychopharmacology, fourth Edition f f
Meyer • Quenzer
f f
Chapter 1: Principles of Pharmacology f f f f
Multiple Choice f
1. refer(s) to specific molecular changes that occur when a drug binds to a f f f f f f f f f f f f
particular target site or receptor, while
f f are the resulting widespread alterations
f f f f f f f f
in function.
f f
a. Drug action; therapeutic effects
f f f
b. Side effects; drug effects
f f f
c. Therapeutic effects; side effects f f f
d. Drug action; drug effects
f f f
Answer: d f
Textbook Reference: Pharmacology: The Science of Drug Action
f f f f f f f
2. After drug administration has occurred, the amount of drug in the blood that is free to
f f f f f f f f f f f f f f f
bind at specific target sites is referred to as
f f f f f f f f f
a. the therapeutic dose.
f f
b. first-pass effects. f
c. bioavailability.
d. ED50.
Answer: c f
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
f f f f f f
3. The specific molecular changes that occur when a drug binds to a particular target site or
f f f f f f f f f f f f f f f
receptor are referred to as
f f f f f
a. drug effects. f
b. drug action. f
c. side effects.f
d. placebo effects. f
Answer: b f
Textbook Reference: Pharmacology: The Science of Drug Action
f f f f f f f
4. Which of the following is not a possible explanation for placebo effects?
f f f f f f f f f f f
a. Pavlovian conditioning f
b. Genetic variation f
c. Drug competition f
d. Expectation of outcome f f
Answer: c f
Textbook Reference: Pharmacology: The Science of Drug Action
f f f f f f f
Page 3 of 247
f f f
, 5. The administration of oxytocin has been proposed as a treatment for autism. f f f f f f f f f f
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c f
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
f f f f f f
6. Which factor does not affect the pharmacokinetics of a drug?
f f f f f f f f f
a. Route of administration
f f
b. Lipid solubility
f
c. Depot binding f
d. Drug actionf
Answer: d f
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
f f f f f f
7. First-pass metabolism occurs when drugs are taken
f f f f f f
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a f
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
f f f f f f
8. The area postrema is one area in the brain where the
f f is not complete. f f f f f f f f f f
a. cerebrospinal fluid f
b. blood–brain barrier f
c. choroid plexus f
d. phospholipid membrane f
Answer: b f
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
f f f f f f
9. First-pass metabolism occurs with orally administered drugs because
f f f f f f f
a. their absorption is slowed by food.
f f f f f
b. drugs absorbed into the bloodstream from the stomach go to the liver on the way to
f f f f f f f f f f f f f f f
general circulation.
f f
c. drugs must first survive the acidic environment of the stomach.
f f f f f f f f f
d. salivary enzymes in the mouth begin the process of metabolism.
f f f f f f f f f
Answer: b f
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
f f f f f f
10. Toxic substances in the blood trigger a vomiting response by activating the
f f f f f f f f f f f
a. blood–brain barrier. f
b. choroid plexus. f
c. area postrema.
f
d. median eminence. f
Page 4 of 247
f f f
