NUR 2063 / NUR2063: Essentials of Pathophysiology

1. What are the functions of the kidneys? - Regulation of blood pressure; regulating blood osmolarity; removal of toxins; blood filtration; activate vitamin D 2. What are the clinical manifestations of benign prostatic hypertrophy? - dribbling; difficulty initiating urine stream; hesitancy; urinary retention, decreased stream 3. What substance controls the reabsorption of water from the collecting ducts? - ADH- Anti Diuretic Hormone 4. What is type 2 diabetes characterized as? - peripheral tissue insulin resistance 5. What are the clinical manifestations of Graves' disease? - Exophthalmos (bulging eyes), goiter, enlarge thyroid, heat intolerance, anxiety- hyperthyroidism 6. What processes occur during fasting? - glucogenesis; glycogenesis 7. What type of tissue is accessed to promote energy production in type 1 diabetes? - adipose/ fat 8. What are the clinical manifestations of hypothyroidism? - myxedema, fatigue, cold sensitivity, constipation, weight gain 9. What are the clinical manifestations of hyperthyroidism? - Goiter, fatigue, weight loss, infertility, memory loss, hair loss, muscle pain 10. What are the clinical manifestation of hyper para thyroidism? - fatigue, body aches, bone pain, depression, headaches, memory loss 11. What are the clinical manifestations of hypo para thyroidism? - numbness, tetany, parathesis, muscle spasms 12. What are the clinical manifestations of ketoacidosis? - fruity breath, drowsiness, nausea, thirst, confusion, lethargy, vomiting 13. What mechanisms control hormone release and regulation? - negative feedback loop NUR 2063 / NUR2063: Essentials of Pathophysiology Exam 2 (Latest 2025) Rasmussen 14. What hormones are released by the anterior pituitary gland? - Growth Hormone, prolactin, follicle stimulating hormone, thyroid stimulating hormone, LH, ACTH and endorphins 15. What is diabetes insipidus? - a disorder caused by inadequate amounts of ADH which causes excessive water loss 16. clinical manifestations of diabetes insipidus - polyuria, nocturia, continuous thirst, and polydipsia 17. clinical manifestations of Cushings syndrome? - Excessive secretion of cortisol causes redistribution of fat, "moon face", "buffalo" hump on the back and pendulous abdomen. - 18. Facial skin is flushed (high blood pressure), skin covering abdomen develops stretch marks - • individual bruises easily and wound healing is poor - 19. Approximately 1/2 develop mental status changes from irritability to severe psychiatric disturbance - Females may experience changes due to increased androgen levels 20. clinical manifestations of secondary hypothyroidism - Weakness. - Fatigue. -Cold intolerance. -Constipation. -Weight gain. -Depression. -Joint or muscle pain. -Brittle fingernails. 21. clinical manifestations of primary hypothyroidism - fatigue. - lethargy. - sensitivity to cold. - depression. - muscle weakness. 22. clinical manifestations of primary aldosteronism - hypertension and hypokalemia 23. clinical manifestations of secondary aldosteronism - High blood pressure. - Low level of potassium in the blood. - Feeling tired all the time. - Headache. - Muscle weakness. - Numbness. 24. What is myxedema? - severe hypothyroidism; non pitting edema 25. What are the causes of hypothyroidism? - Hashimoto's disease: most common when the immune system attacks the thyroid cells - after surgical or radioactive treatment for hyperthyroidism - head or neck radiation for cancer - iodine deficiency 26. What are the three p's in diabetes? - polydipsia, polyuria, polyphagia 27. What is the difference between primary and secondary endocrine disorders? - Primary endocrine disease inhibits the action of downstream glands, malfunction of the hormone producing gland; Secondary endocrine disease is indicative of a problem with the pituitary gland. 28. What is the cause of Cushing syndrome? - Excessive corticosteroids 29. What is acute gastritis? - Transient inflammation of the gastric mucosa 30. What is chronic gastritis? - Chronic mucosal inflammatory changes leading to atrophy and intestinal metaplasia. This is mostly due to H. Pylori, but in some cases it can be autoimmune. 31. What causes gastritis? - Acute - circulatory disturbances (shock) and exposure to exogenous irritants (drugs [aspirin], alcohol, chemicals, lactose intolerance) Chronic - cause is unknown is probably mediated by immunologic mechanism or related to infection with H. pylori 32. What is amenorrhea? – - absence of menstruation 33. What is metrorrhagia? – - bleeding between periods 34. What is dysmenorrhea? – - painful periods 35. Costal vertebral angle (CVA) - angle formed by the 12th rib and the vertebral column on the posterior thorax, overlying the kidney; percuss for kidney tenderness 36. What causes flank pain? - kidney stones 37. When is enuresis abnormal? - after age 5 38. People with polycystic kidney disease should do what? - increase fluid intake, measure blood pressure regularly 39. What is polyuria? - frequent urination 40. Female Mutilation - risks for uti, trouble urinating 41. What hormone causes bleeding during menopause? - estrogen 42. Where does exchange occur in the kidneys? - As the filtered fluid moves along the tubule, the blood vessel reabsorbs almost all of the water, along with minerals and nutrients your body needs. The tubule helps remove excess acid from the blood. The remaining fluid and wastes in the tubule become urine. 43. What increases the risk for bladder cancer? - smoking 44. What is the kidney filtration path? - Bowmans capsuleproximal tubuleloop of henledistal tubule 45. What causes increase in glumerial filtration? - increase capillary hydrostatic pressure 46. What is cystitis? - inflammation of the urinary bladder; UTI, painful burning, itching, 47. What is a hydrocele? - Fluid collection within the tunica vaginalis 48. What are the symptoms of prositis? - pain, fever, trouble urinating, trouble with urine retention 49. What is renal colic? - kidney stone related pain 50. What is the bacteria associated with syphilis? - anaerobic spirochetes 51. What are complications of syphilis? - vascular problems, cardiovascular, aortic stenosis, inflamed aorta, aorta necrosis, brain aneurysm, blindness, numbness, tingly, loopyness 52. What end periods? - anorexia, menopause, pregnancy, hypothyroidism, adenomas and carcinomas 53. When is RAS activated? - low BP 54. Treatment for herpes - Acyclovir, sitz bath, dry heat 55. symptoms of post streptococcal glomerulonephritis - dark urine 56. What causes acromegaly? - excessive GH during adulthood 57. Primary hypothyroidism levels - low T4, high TSH 58. Secondary hypothyroidism levels - low T3, T4 and TSH 59. What is gigantism? - hypersecretion of GH in children 60. What is diabetes insipidus? - a disorder caused by inadequate amounts of ADH which causes excessive water loss 61. What is SIADH? - syndrome of inappropriate antidiuretic hormone; too much sodium secretion 62. What is the tumor of the adrenal gland? - Pheochromocytoma