Test Bank for Understanding Pharmacology
Essentials for Medication Safety, 2nd Edition by
M. Linda Workman & LaCharity ISBN
9781455739769 Chapter 1-32 | Complete Guide A+
What is the therapeutic objective of drug therapy? - Answerto provide maximum benefit with minimum
harm
drug - Answerany chemical that can affect living processes
pharmacology - Answerthe study of drugs and their interactions with living systems
clinical pharmacology - Answerthe study of drugs in humans
Properties of an Ideal Drug - Answer- effectiveness: most important property, elicits the response for
which it was given
- safety: ability to not produce harmful effects, even at high doses and over long periods
- selectivity: elicits only the response for which it was given
additional properties of an ideal drug - Answerreversible action
predictability
ease of administration
, freedom from drug interactions
low cost
chemical stability
simple generic name
pharmacokinetics - Answerstudy of drug movement throughout the body (impact of the body on drugs)
4 major pharmacokinetic processes - Answerdrug absorption, drug distribution, drug metabolism, drug
excretion
absorption - Answermovement of drug from the administration site to the systemic circulation (blood)
enteral (GI) - Answerthrough stomach mucosa or small intestine (oral, TF, sublingual, buccal, rectal)
oral (PO) - Answerbarriers to absorption: epithelial lining of GI tract, capillary wall
absorption pattern: slow & variable
advantages: easy, convenient, inexpensive, ideal for self-med, potentially reversible
disadvantages: variability, inactivation of some drugs by gastric acid & digestive enzymes, possible
nausea & vomiting from local irritation, patient must be conscious & cooperative
pharmaceutical preparations for oral administration - Answertablets, enteric-coated preparations, and
sustained- release preparations
parenteral - Answerany other route than GI tract (IV, IM, SC, intra-dermal, intra-arterial, intra-hecal)
intravenous (IV) - Answerbarriers to absorption: none
absorption pattern: instantaneous
advantages: rapid onset, more ideal for emergencies, precise control over drug levels, use of large fluid
volumes, permits use of irritant drugs
Essentials for Medication Safety, 2nd Edition by
M. Linda Workman & LaCharity ISBN
9781455739769 Chapter 1-32 | Complete Guide A+
What is the therapeutic objective of drug therapy? - Answerto provide maximum benefit with minimum
harm
drug - Answerany chemical that can affect living processes
pharmacology - Answerthe study of drugs and their interactions with living systems
clinical pharmacology - Answerthe study of drugs in humans
Properties of an Ideal Drug - Answer- effectiveness: most important property, elicits the response for
which it was given
- safety: ability to not produce harmful effects, even at high doses and over long periods
- selectivity: elicits only the response for which it was given
additional properties of an ideal drug - Answerreversible action
predictability
ease of administration
, freedom from drug interactions
low cost
chemical stability
simple generic name
pharmacokinetics - Answerstudy of drug movement throughout the body (impact of the body on drugs)
4 major pharmacokinetic processes - Answerdrug absorption, drug distribution, drug metabolism, drug
excretion
absorption - Answermovement of drug from the administration site to the systemic circulation (blood)
enteral (GI) - Answerthrough stomach mucosa or small intestine (oral, TF, sublingual, buccal, rectal)
oral (PO) - Answerbarriers to absorption: epithelial lining of GI tract, capillary wall
absorption pattern: slow & variable
advantages: easy, convenient, inexpensive, ideal for self-med, potentially reversible
disadvantages: variability, inactivation of some drugs by gastric acid & digestive enzymes, possible
nausea & vomiting from local irritation, patient must be conscious & cooperative
pharmaceutical preparations for oral administration - Answertablets, enteric-coated preparations, and
sustained- release preparations
parenteral - Answerany other route than GI tract (IV, IM, SC, intra-dermal, intra-arterial, intra-hecal)
intravenous (IV) - Answerbarriers to absorption: none
absorption pattern: instantaneous
advantages: rapid onset, more ideal for emergencies, precise control over drug levels, use of large fluid
volumes, permits use of irritant drugs
