PATH 3610 :MIDTERM 2 EXAM
QUESTIONS WITH ACCURATE
SOLUTIONS
Which of the following terms describe an exudate?
a. formed due to increase in venous hydrostatic pressure
b. contains plasma ultrafiltrate primarily
c. contains fluid, protein, and inflammatory cells -- Answer ✔✔ c
The specific movement of neutrophils toward a focus of inflammation is
termed:
a. peristalsis
b. chemotaxis
c. margination -- Answer ✔✔ b
The systemic fever response is a result of which of the following?
,a. pyrogens influencing the hypothalamic thermoregulatory centre in
the brain
b. a loss of vasomotor control due to bacterial toxins
c. decreased heat loss from the body due to peripheral
vasoconstriction -- Answer ✔✔ a
Which of the following lists best describes the composition of pus?
a. plasma, fibrin, tissue macrophages and tissue debris
b. neutrophils, mucus, tissue debris
c. degenerating neutrophils, plasma, tissue debris and dead microbes
-- Answer ✔✔ c
An active increase in blood flow to a tissue area is termed:
a. hemorrhage
b. hyperemia
c. congestion -- Answer ✔✔ b
Which of the following statements about acute inflammation is not
true?
a. it is the first line of defense against an injury
,b. the extent of the inflammatory reaction is proportionate to the
degree of tissue damage
c. the leakiness of the vessels allows fluids and proteins but not cells to
escape -- Answer ✔✔ c
The increased vascular permeability seen early in acute inflammation
is primarily the
result of:
a. widening of intercellular junctions between endothelial cells
b. leukocyte-mediated endothelial injury
c. direct injury to endothelium by the initiating cause of the
inflammation -- Answer ✔✔ a
Mast cells have an important role in inflammation because their
granules release:
a. serotonin
b. histamine
c. proteases -- Answer ✔✔ b
Fibrinous inflammation develops when:
a. inflammation is caused by bacterial invasion
, b. vascular permeability has increased sufficiently to allow fibrinogen
to leave the vessels
c. clotting is initiated in vessels -- Answer ✔✔ b
Number 10. Opsonization refers to the:
a. enhanced phagocytosis of injurious agents by leucocytes
b. activation of mediator precursors
c. enhanced recognition by leucocytes of injurious agents, due to
coating with a variety of opsonins -- Answer ✔✔ c
granulation tissue is characterized by (2): -- Answer ✔✔ fibrosis and
angiogenesis (formation of new blood vessels)
The main leukocytes of acute inflammation are: -- Answer ✔✔
neutrophils
What are the 2 major vascular changes of acute inflammation? --
Answer ✔✔ - increased permeability of vessels
- vascular dilation
What is the main cellular response of acute inflammation? -- Answer
✔✔ Leukocytes leave circulation and go to site of injury
QUESTIONS WITH ACCURATE
SOLUTIONS
Which of the following terms describe an exudate?
a. formed due to increase in venous hydrostatic pressure
b. contains plasma ultrafiltrate primarily
c. contains fluid, protein, and inflammatory cells -- Answer ✔✔ c
The specific movement of neutrophils toward a focus of inflammation is
termed:
a. peristalsis
b. chemotaxis
c. margination -- Answer ✔✔ b
The systemic fever response is a result of which of the following?
,a. pyrogens influencing the hypothalamic thermoregulatory centre in
the brain
b. a loss of vasomotor control due to bacterial toxins
c. decreased heat loss from the body due to peripheral
vasoconstriction -- Answer ✔✔ a
Which of the following lists best describes the composition of pus?
a. plasma, fibrin, tissue macrophages and tissue debris
b. neutrophils, mucus, tissue debris
c. degenerating neutrophils, plasma, tissue debris and dead microbes
-- Answer ✔✔ c
An active increase in blood flow to a tissue area is termed:
a. hemorrhage
b. hyperemia
c. congestion -- Answer ✔✔ b
Which of the following statements about acute inflammation is not
true?
a. it is the first line of defense against an injury
,b. the extent of the inflammatory reaction is proportionate to the
degree of tissue damage
c. the leakiness of the vessels allows fluids and proteins but not cells to
escape -- Answer ✔✔ c
The increased vascular permeability seen early in acute inflammation
is primarily the
result of:
a. widening of intercellular junctions between endothelial cells
b. leukocyte-mediated endothelial injury
c. direct injury to endothelium by the initiating cause of the
inflammation -- Answer ✔✔ a
Mast cells have an important role in inflammation because their
granules release:
a. serotonin
b. histamine
c. proteases -- Answer ✔✔ b
Fibrinous inflammation develops when:
a. inflammation is caused by bacterial invasion
, b. vascular permeability has increased sufficiently to allow fibrinogen
to leave the vessels
c. clotting is initiated in vessels -- Answer ✔✔ b
Number 10. Opsonization refers to the:
a. enhanced phagocytosis of injurious agents by leucocytes
b. activation of mediator precursors
c. enhanced recognition by leucocytes of injurious agents, due to
coating with a variety of opsonins -- Answer ✔✔ c
granulation tissue is characterized by (2): -- Answer ✔✔ fibrosis and
angiogenesis (formation of new blood vessels)
The main leukocytes of acute inflammation are: -- Answer ✔✔
neutrophils
What are the 2 major vascular changes of acute inflammation? --
Answer ✔✔ - increased permeability of vessels
- vascular dilation
What is the main cellular response of acute inflammation? -- Answer
✔✔ Leukocytes leave circulation and go to site of injury
