Pathophysiology D115 WGU EXAM 2025/2026
, Pathophysiology D115 WGU EXAM 2025/2026
1. Turner Syndrome A chromosomal disorder in females in which either
an X chromosome is missing, making the person XO
instead of XX, or part of one X chromosome is
deleted.
2. Tay-Sachs disease A human genetic disease caused by a recessive allele
that leads to the accumulation of certain lipids in the
brain. Seizures, blindness, and degeneration of
motor and mental performance usually become
manifest a few months after birth.
3. Down Syndrome a condition of mild to severe intellectual disability
and associated physical disorders caused by an extra
copy of chromosome 21
4. Marfan Syndrome autosomal dominant trait..
a genetic disorder that changes the proteins that
help make healthy connective tissue. This leads to
problems with the development of connective tissue,
which supports the bones, muscles, organs, and
tissues in your body.
5. Marfans syndrome genetic
Autosomal dominant. inherited in an autosomal
trait type
pattern which means one copy of the altered gene in
each cell is sufficient to cause the disorder.
6. What causes Marfan's Defects or deletions (pathogenic variants) of the
syndrome? fibrillin-1 (FBN1) gene have been shown to cause
Marfans syndrome
at least 25% of Marfan syndrome cases result from a
new mutation in the FBN1 gene
7. spina bifida a congenital defect that occurs during early pregnancy
when the spinal canal fails to close completely around
the spinal cord to protect it
, Pathophysiology D115 WGU EXAM 2025/2026
8. What can cause Spina Bi- Decreased folic acid or maternal use of
valproic acid fida
9. Turner syndrome characteristics
Underdeveloped ovaries
(sterile) Short stature (~
4'7")
Webbing of the neck
Edema
Underdeveloped breasts; wide nipples
High number of aborted fetuses
10. Diagnostic testing for genetic testing , echo, bone density, and bone age testing
are neces-
Turner's syndrome sary.
11. Treatment of Turners Treatment involves estrogen therapy and growth hormone
administrasyndrome tion. Treat symptomatically for all other effects of the dz.
12. Cushing's Syndrome a condition caused by prolonged exposure to high levels of
cortisol
13. Cushing syndrome fatty hump between shoulders, a rounded face(moon faced),
and pink symptoms or purple stretch marks on skin, thinning fragile skin, slow
healing of
cuts, insect bites and infections, acne, decreased
libido, decreased fertility, irregular or absent
menstrual periods, fatigue, muscle weakness,
cognitive difficulties, and headaches.
14. Viral hemorragic fevers spread by contact with infected animals or insects. Most
common hosts are mosquitos, ticks, rodents, or bats.
, Pathophysiology D115 WGU EXAM 2025/2026
1. Turner Syndrome A chromosomal disorder in females in which either
an X chromosome is missing, making the person XO
instead of XX, or part of one X chromosome is
deleted.
2. Tay-Sachs disease A human genetic disease caused by a recessive allele
that leads to the accumulation of certain lipids in the
brain. Seizures, blindness, and degeneration of
motor and mental performance usually become
manifest a few months after birth.
3. Down Syndrome a condition of mild to severe intellectual disability
and associated physical disorders caused by an extra
copy of chromosome 21
4. Marfan Syndrome autosomal dominant trait..
a genetic disorder that changes the proteins that
help make healthy connective tissue. This leads to
problems with the development of connective tissue,
which supports the bones, muscles, organs, and
tissues in your body.
5. Marfans syndrome genetic
Autosomal dominant. inherited in an autosomal
trait type
pattern which means one copy of the altered gene in
each cell is sufficient to cause the disorder.
6. What causes Marfan's Defects or deletions (pathogenic variants) of the
syndrome? fibrillin-1 (FBN1) gene have been shown to cause
Marfans syndrome
at least 25% of Marfan syndrome cases result from a
new mutation in the FBN1 gene
7. spina bifida a congenital defect that occurs during early pregnancy
when the spinal canal fails to close completely around
the spinal cord to protect it
, Pathophysiology D115 WGU EXAM 2025/2026
8. What can cause Spina Bi- Decreased folic acid or maternal use of
valproic acid fida
9. Turner syndrome characteristics
Underdeveloped ovaries
(sterile) Short stature (~
4'7")
Webbing of the neck
Edema
Underdeveloped breasts; wide nipples
High number of aborted fetuses
10. Diagnostic testing for genetic testing , echo, bone density, and bone age testing
are neces-
Turner's syndrome sary.
11. Treatment of Turners Treatment involves estrogen therapy and growth hormone
administrasyndrome tion. Treat symptomatically for all other effects of the dz.
12. Cushing's Syndrome a condition caused by prolonged exposure to high levels of
cortisol
13. Cushing syndrome fatty hump between shoulders, a rounded face(moon faced),
and pink symptoms or purple stretch marks on skin, thinning fragile skin, slow
healing of
cuts, insect bites and infections, acne, decreased
libido, decreased fertility, irregular or absent
menstrual periods, fatigue, muscle weakness,
cognitive difficulties, and headaches.
14. Viral hemorragic fevers spread by contact with infected animals or insects. Most
common hosts are mosquitos, ticks, rodents, or bats.
