82 Pages APEA Predictor Exam – Questions, Correct Answers and Rationale Pre-Predictor 2025/2026 NEWEST VERSION HIGHEST SCORE| FREE PDF DOWNLOAD

South UniversityWeek 4APEAPredictor Exam– Pre-
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Predictor Test latest 2025 (Q&A with Rationales)
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Typed Pre-Predictor ka




1) A 15 years old high school student with a mild sore throat and low-grade fever that has
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persisted for about 3 weeks. She reports general malaise, fatigue, and loss of appetite. The NP
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suspects mononucleosis. Which of the following is the LEAST appropriate intervention?
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a. Palpate the lymph nodes and spleen
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b. Examinethe posterior oropharynx for petechiae
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,c. Obtaina CBC,throat culture, and heterophil antibody test. ka ka ka ka ka ka ka ka




d. Obtain an urinalyses and serum for LFTs and amylase ka ka ka ka ka ka ka ka




Explanation: mononucleosis is a symptomatic infection caused by the Epstein-Bar virus. Common ka ka ka ka ka ka ka ka ka ka ka




is people 15-24 years of age. Common signs and symptoms following incubation period (1-2
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months) include fatigue, chills, malaise, anorexia, white tonsillar exudates and lymphadenopathyor
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posterior cervicalregion. Splenomegalycan bepresent. Amaculopapular or occasionally a petechial
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rash occurs in less than 15% of patients. A diagnosis is usually made usingtheMonospot. In addition,
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neutropenia and lymphocytosisare usuallydetected intheCBC.
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2) A 32 years old male patient complaint of urinary frequency and burning on urination for 3 days.
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Urinalyses reveals bacteriuria and positive nitrites. He denies any past hx. Of urinary tract infections.
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The initial treatment should be:
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a. trimethoprim-sulfamethoxazole(Bactrim, Sulfatrim) for7-10day ka ka ka ka ka




b. ciprofloxacin (Cipro) for 3-5 days ka ka ka ka




c. Trimethoprim-Sulfamethoxazolefor3days ka ka ka




d. 750 mg ciprofloxacin as a one-time dose ka ka ka ka ka ka




Explanation: trimethoprim-sulfamethoxazole(TMPS)isusuallynappropriatemedicationto treat ka ka ka ka ka ka ka ka ka




urinary tract infections in most patients. In the case of community resistance to TMPS
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>20%^, another medication shouldbe substituted. In men, the appropriate length of timeis 7-10 days.
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Women may be treated for 3 days for uncomplicated UTI
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3) Whichagent ismost effective for the treatment of nodulocystic acne? ka ka ka ka ka ka ka ka ka ka




a. Benzoyl peroxide(Benzac) ka ka




b. Retinoicacid (RetinA) ka ka ka




c. Topicaltetracycline ka




d. Isotretinoin)

Explanation: Isotretinoin (Accutane) is a systemic agent indicated for treatment with severe ka ka ka ka ka ka ka ka ka ka ka




inflammatoryacne. Guidelines for itsuse must be clearly understood by the patient.Awoman of
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childbearing age must use an effective method of contraception because isotretinoin is teratogenic.
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There are manyrestrictions inprescribingthismedicationbecauseof theteratogenic effects is given
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during pregnancy. Therefore, it is a pregnancy category X.
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4) An 18 y/o woman is taking a combined hormonal oral contraceptive. She should be
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instructed to use a backup method for the prevention of pregnancy
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a. Throughout theweek of placebo pills ka ka ka ka ka




b. Ifprescribed topiramate(Topamax)forthetreatment ofmigraines.
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,c. Ifprescribed amoxicillin/clavulanate(Augmentin) for asinus infection
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d. if she forgets to take a single dose of the contraceptive
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Explanation: Anticonvulsant including phenytoin (Dilantin), carbamazepine (Tegretol), ka ka ka ka ka ka




primidone (Mysoline), topiramate (Topamax) and oxcarbazepine (Trileptal) reduce the
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effectivenessofcontraceptives.Depo-medroxyprogesteroneacetate injectionsorlevonorgestrel-
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releasing intrauterine devices would be a better method of contraceptive for patients taking
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anticonvulsants. Most commonly used antibiotics have not been proven to reduce the effectiveness
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of contraceptives. Rifampin is an exception, and additional …. Be used by women taking this drug
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and using oral contraceptives, transdermal, or vaginal ring preparations.
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Additional backup contraception should be used if taking antifungal agents. No additional protection
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isneeded thought the week of placebo pills. Missingone single dose of contraceptive does not require
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additional protection, missing more than one doses does.
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5) A 44 years old female patient has diabetes. Her total cholesterol (TC) is 250 mg/dl (6.5 mmol/L),
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LDL= 190 mg/dL (4.94 mmol/L), HDL= 25 mg/dL (65 mmol/L), and triglycerides= 344 mg/dL(8.94
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mmol/L).What agent have thegreatest effect onimprovingher lipidprofile and reducing morbidity and
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mortality associates with dyslipidemia?
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a. Niacin(Niaspan) ka




b. Atorvastatin
c. Omega 3 fatty acids ka ka ka




d. Fenofibrates
Explanation: First and foremost, it is essential to educate individuals on a heart-healthy lifestyle. ka ka ka ka ka ka ka ka ka ka ka ka ka




LDL-C isone of the major culprits inthe development of atherosclerotic heart disease. The target level
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of LDL-C is between 50 to 70mg/dl to prevent plaque formation in the blood vessels. Guidelines
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strongly recommend statin therapy because they primarily lower LDL-C levels, but they also have
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the secondary effects of lowering triglyceride and increasing HDL-C levels.
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6) A30yearsoldfemalecomesintoa clinic with classic signs and symptoms of appendicitis. The NP
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fails to refer the patient to a surgeon. The appendix ruptures and the woman die. This is an example of
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a. Failure of diligence ka ka




b. Professionalliability ka




c. Negligence
d. Malpractice

Explanation:malpractice,anegligence tort,occurs whenahealthcareprofessional’sactionsfall ka ka ka ka ka ka ka ka ka ka ka ka




bellow the appropriate standard of care and hurts the patient. In this case the patient came with sings
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and symptoms indicating appendicitis and the NP failed to refer the patient..
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7) ANPhasrecentlybeenhiredtoworkina fasttrackfacility. The NP employer asked if she has
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“a problem prescribing medications for emergency contraception.” The NP replies
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affirmatively. This is:
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a. Grounds for dismissal ka ka




b. An ethical dilemma for the NP ka ka ka ka ka




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, c. Illegal according to the standards of nursing ka ka ka ka ka ka




d. Patient abandonment. ka




Explanation: inthisinstance, the NPhasa difference of opinionwithher employer based onher ka ka ka ka ka ka ka ka ka ka ka ka ka ka ka ka




religious or moral belief about providing emergency contraception. This situation is an example of an
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ethical dilemma. Failure to participate in the provision of care to the patient based on the NP’s beliefs
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is neither against the law nor a violation of the standards of practice
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8) Apatientpresentswithpruriticlesions on both knees. There are visiblesilverscales. How
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Should this condition be managed?
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a. Topicalantifungalcreamorointment ka ka ka ka




b. Oral antibiotics ka




c. Topicalcorticosteroidscream ka ka




d. Topicalanti-fungal/steroidcream ka ka ka




Explanation: Psoriasisischaracterizedbyerythematouspapules,aswellasitchy, red,precisely ka ka ka ka ka ka ka ka ka ka ka ka




defined plaques with silvery scales. Auspitz sings is another common finding. Topical agents
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containingtarand salicylicacidmay beused.Topical steroids,suchasbetamethasone, mayalso be
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ordered.
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9) Antidepressantdiscontinuationsyndrome is less likelyif the patient ka ka ka ka ka ka ka ka




a. Is male ka




b. Is less than 35 y/o
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c. Has taken an SSRI with a short half life
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d. Gradually tapers SSRI use ka ka ka




Explanation: Antidepressant discontinuation syndrome is most often seen in the primary care office ka ka ka ka ka ka ka ka ka ka ka ka




in association with SSRI discontinuation, because SSRIs are the most commonly prescribed class of
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antidepressant medications. Interruption of treatment with an anti-depressant medication is
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sometimes associated with an antidepressant discontinuation syndrome; in early reports itwas
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referred to as a “withdrawal reaction. Symptoms of antidepressant discontinuation syndrome can
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include flu-like symptoms, insomnia, nausea, imbalance, sensory disturbances, and hyperarousal.
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Tapering is recommended by experts.
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10) Patient withbenign prostatic hyperplasia (BPH) shouldbe taught toavoid whichone ofthe
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following drug classes?
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a. Alphaadrenergic antagonist ka ka




b. Anti-androgenagents ka




c. Tricyclicantidepressant(TCA) ka ka




d. Sulfonamides
Explanation: tricyclic antidepressant should not be used by men with benign prostatic hyperplasia ka ka ka ka ka ka ka ka ka ka ka ka




because ofthe increasedrisk ofurinary retention secondary totheanticholigergic effects of TCAs.
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11) Which of thefollowing is thebest response to awoman who has just admitted sheis a victim
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of spousal abuse?
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a. What was if you did tomake him angry? ka ka ka ka ka ka ka ka




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