Three Phases of Medication Administration - ANS-Pharmaceutic Phase, Pharmacokinetic
Phase, and Pharmacodynamic Phase
three Properties for an Ideal Drug - ANS-There is no "perfect" drug, each drug may have a side
effect. We need the max gain with minimal damage. Weigh the pro's and con's.
Effectiveness, Safety, and Selectivity.
5 Rights to Medication Administration - ANS-right affected person, proper med, proper dose,
proper course, right time
Additional: Documentation
6 Possible Consequences of healing importance for metabolism - ANS-1. Accelerated renal
excretion of medicine (liver is running too nicely)
2. Drug Inactivation
three. Increased healing motion
4. Activation of "prodrugs" (inactive compound turns into lively)
5. Increased toxicity
6. Decreased toxicity
Additive Effect - ANS-1+1=2
* pills with similar actions are taken for an increased effect
*undesired: hydralazine & nitro
*favored: beta blocker + diuretic
Adrenergic Agonist - ANS-Epinephrine: used to tx hypersensitive reaction and allergies, intense
hypotension
Albuterol: used to tx bronchioconstriction
Adverse consequences: tachycardia.
Adrenergic Blocker - ANS-*Beta Blockers (the LOL's): block outcomes of epinephrine and
norepinephrine at beta sites, impacts the coronary heart and airway.
-lower bp, hr, reason bronchoconstriction
-i.E. Metopropolol, atenolol, labetolol.
-used to tx HTN, migraine prophylaxis, angina, MI, coronary heart failure
Side Effects: Depression, sexual dysfunction, cool extremities, bronchoconstiriction
*Contraindicated in bronchospasm!!
Adverse Effect - ANS-Responses inside the body where the drug's consequences are both
unwanted and harmful.
, Adverse Reactions - ANS-unintentional, undesirable, unexpected reaction that occur at ordinary
doses.
*Must file and report as they constitute variances in the remedy
*Varies from drowsiness to anaphylaxis
After a pill is taken PO what organ has a major impact on it is bioavailability? - ANS-The liver
Agonist - ANS-Drugs that mimic or produce an effect (Example: epinephrine)
Allergic Reaction - ANS-an immune response to a drug, after earlier sensitization has occurred
*Rash to anaphylaxis
*Nurses reaction to "do you've got any allergies" subsequent query is "what occurs while you
take this?"
Alzheimer's disorder Medications: Cholinesterase Inhibitor - ANS-donepezil: prevents the
breakdown of acetylcholine, allowing more acetylcholine to interact and enhance cognitive
feature
*Does no longer forestall or gradual disease. Has shown prolonged impartial characteristic and
might slow loss of reminiscence and cognition.
*Side Effects: Bronchoconstriction, bradycardia, Dyspepsia,
Alzheimer's sickness: NMDA Receptor Agonist - ANS-Mematine: (modulates the glomulate)
which play a critical role in learning and memory.
*Side results: Constipation, confusion, HA, Dizziness.
*Helps signs and symptoms, does no longer tx underlying disorder
Amphetamine-like capsules - ANS-Stimulate the combat or flight response
*Methylphenidate and dexmethylphenidate
-Side effects: Insomnia, anxiety like symptoms, HTN, weight loss, cardiac dysrythmias, urge for
food suppression
*example: If you are walking from the bear you are now not dozing
Antagonist - ANS-Drugs that prevent or block a response (example: metoprolol)
Antagonist Effect - ANS-When 2 capsules are given collectively, one drug interferes with the
motion of the other
*Cancel each other out
*Undesirable: albuterol and aterolol
*Desirable: Morphine and Naloxone
Anticholinergics - ANS-Anticholinergic Effects can't see, spit, pee, can't poop.
AR: Sympathetic effects
*Drugs: "-ine."