PATH3610 Midterm 2 Exam Questions With
Answers 100% Pass
T/F. Inflammatory cell movement into an area of acute inflammation is a passive process
- ANSWER False
Epithelioid cells have: - ANSWER an increased ability to secrete lysozyme
A surgical sponge (gauze) mistakenly left in the abdominal cavity would cause: -
ANSWER foreign body granuloma
Exudation refers to: - ANSWER increased movement of fluid and proteins out of vessels
due to increased permeability
Chronic suppurative inflammation is characterized: - ANSWER necrosis, pus formation,
fibrosis and mononuclear cells
Increased vascular permeability in inflammation will allow large protein molecules to
leave the vascular space. These include: - ANSWER fibrinogen
Septicemia refers to: - ANSWER spread of bacteria and their toxins via the bloodstream
The most common cause of osteomyelitis is: - ANSWER bacterial seeding from the blood
The role of T-cells in granulomatous inflammation is to: - ANSWER produce lymphokines
which inhibit macrophage migration
Inflammatory mediators which have a role in signalling pain include: - ANSWER
bradykinin, histamine, serotonin
Neutrophil diapedesis is assisted by: - ANSWER enlarged endothelial pores
T/F. Persistence of an antigen or injurious stimulus will cause chronic inflammation to
develop - ANSWER True
Cross-linking of numbers of antibody and antigen units leads to: - ANSWER agglutination
Amplification or expansion of the immune response is characteristic of: - ANSWER both
of the above (the B and T cell response to antigen)
Sites of lymphocyte priming are the: - ANSWER thymus and bone marrow
A classic example of delayed type of hypersensitivity is: - ANSWER the tuberculin
reaction
Nonspecific defense mechanisms - ANSWER include all defense mechanisms other than
the immune response
, Immune complex formation may cause: - ANSWER complement activation
The defining characteristics of AIDS is: - ANSWER reduced numbers of CD4+ T cells
During the lag period of the primary immune response, B cells with receptors for the
specific antigen: - ANSWER undergo clonal expansion to produce a large number of
plasma cells
In Type II (antibody-dependent) hypersensitivity, antibody is: - ANSWER directed against
specific antigens on cell surfaces
Lymph nodes which are enlarged because of response to an antigenic stimulus are
termed: - ANSWER reactive
Molecules which evoke an immune response when introduced into a host are termed: -
ANSWER antigens
The lack of response to our own antigens is termed: - ANSWER self tolerance
Complete the following statement correctly: immune suppression can: - ANSWER result
from therapy with corticosteroids
Hypersensitivity refers to a state: - ANSWER in which the immune response is
destructive rather than neutralizing or defensive
T/F. The similarity between donor and recipient with regard to histocompatibility
antigens is a major determinant of success of tissue and organ transplants - ANSWER
True
The systemic reactions of anaphylaxis are caused by: - ANSWER mast cell
degranulation and mediator release
The end result of immune-complex mediated hypersensitivity is: - ANSWER fibrinoid
necrosis of small vessels (necrotizing vasculitis)
Vaccination is used to produce immunity against infectious organisms, by inducing: -
ANSWER the primary immune response
The acute inflammatory process may cause: - ANSWER an elevated number of white
blood cells in the peripheral blood
Neutrophils leave capillaries in inflammation by the process of: - ANSWER diapedesis
T/F. Following tissue injury, there is an early and transient vasoconstriction - ANSWER
True
Tuberculosis is characterized by: - ANSWER granulomatous inflammation in lungs or
other tissues
The mononuclear cell type with the greatest role in acute inflammation is the: - ANSWER
Answers 100% Pass
T/F. Inflammatory cell movement into an area of acute inflammation is a passive process
- ANSWER False
Epithelioid cells have: - ANSWER an increased ability to secrete lysozyme
A surgical sponge (gauze) mistakenly left in the abdominal cavity would cause: -
ANSWER foreign body granuloma
Exudation refers to: - ANSWER increased movement of fluid and proteins out of vessels
due to increased permeability
Chronic suppurative inflammation is characterized: - ANSWER necrosis, pus formation,
fibrosis and mononuclear cells
Increased vascular permeability in inflammation will allow large protein molecules to
leave the vascular space. These include: - ANSWER fibrinogen
Septicemia refers to: - ANSWER spread of bacteria and their toxins via the bloodstream
The most common cause of osteomyelitis is: - ANSWER bacterial seeding from the blood
The role of T-cells in granulomatous inflammation is to: - ANSWER produce lymphokines
which inhibit macrophage migration
Inflammatory mediators which have a role in signalling pain include: - ANSWER
bradykinin, histamine, serotonin
Neutrophil diapedesis is assisted by: - ANSWER enlarged endothelial pores
T/F. Persistence of an antigen or injurious stimulus will cause chronic inflammation to
develop - ANSWER True
Cross-linking of numbers of antibody and antigen units leads to: - ANSWER agglutination
Amplification or expansion of the immune response is characteristic of: - ANSWER both
of the above (the B and T cell response to antigen)
Sites of lymphocyte priming are the: - ANSWER thymus and bone marrow
A classic example of delayed type of hypersensitivity is: - ANSWER the tuberculin
reaction
Nonspecific defense mechanisms - ANSWER include all defense mechanisms other than
the immune response
, Immune complex formation may cause: - ANSWER complement activation
The defining characteristics of AIDS is: - ANSWER reduced numbers of CD4+ T cells
During the lag period of the primary immune response, B cells with receptors for the
specific antigen: - ANSWER undergo clonal expansion to produce a large number of
plasma cells
In Type II (antibody-dependent) hypersensitivity, antibody is: - ANSWER directed against
specific antigens on cell surfaces
Lymph nodes which are enlarged because of response to an antigenic stimulus are
termed: - ANSWER reactive
Molecules which evoke an immune response when introduced into a host are termed: -
ANSWER antigens
The lack of response to our own antigens is termed: - ANSWER self tolerance
Complete the following statement correctly: immune suppression can: - ANSWER result
from therapy with corticosteroids
Hypersensitivity refers to a state: - ANSWER in which the immune response is
destructive rather than neutralizing or defensive
T/F. The similarity between donor and recipient with regard to histocompatibility
antigens is a major determinant of success of tissue and organ transplants - ANSWER
True
The systemic reactions of anaphylaxis are caused by: - ANSWER mast cell
degranulation and mediator release
The end result of immune-complex mediated hypersensitivity is: - ANSWER fibrinoid
necrosis of small vessels (necrotizing vasculitis)
Vaccination is used to produce immunity against infectious organisms, by inducing: -
ANSWER the primary immune response
The acute inflammatory process may cause: - ANSWER an elevated number of white
blood cells in the peripheral blood
Neutrophils leave capillaries in inflammation by the process of: - ANSWER diapedesis
T/F. Following tissue injury, there is an early and transient vasoconstriction - ANSWER
True
Tuberculosis is characterized by: - ANSWER granulomatous inflammation in lungs or
other tissues
The mononuclear cell type with the greatest role in acute inflammation is the: - ANSWER
