Questions and CORRECT Answers
When do you give hydroxyurea or interferon-a to a polycythemia vera pt in addition to
phlebotomy? - CORRECT ANSWER - When they have additional risk factors - age over
60, hx of thromboembolic event
Treatment for polycythemia vera - CORRECT ANSWER - ASA 81 and phlebotomy to
target hematocrit 45% or less
Imantinib - CORRECT ANSWER - Tyrosine kinase inhibitor used in CML,
gastrointestinal stromal tumors (GIST)
Where is Coccidioidomycosis endemic? - CORRECT ANSWER - Southwestern US
(Southern Cali, Texas, Arizona, New Mexico)
How to treat Coccidioidomycosis? - CORRECT ANSWER - 1st line - Fluconazole
2nd line - Ampho B
What cancer is Sjogren's syndrome associated with? - CORRECT ANSWER - Lymphoma
- 5% lifetime risk
Classic radiographic finding associated with sarcoidosis - CORRECT ANSWER - CXR
bilateral hilar lymphadenopathy
Treatment for stage I pulmonary sarcoidosis - CORRECT ANSWER - Observation - will
probably regress and resolve
For later stages, steroids
, Crystals associated with Calcium Pyrophosphate Deposition Disease - CORRECT
ANSWER - Weakly positively birefringent, Rhomboid-shaped
What is pulsus paradoxus - CORRECT ANSWER - When the systolic pressure falls more
than 10 mm hg with inspiration. Key finding in cardiac tamponade
Pirfenidone - CORRECT ANSWER - Antifibrotic agent used to treat idiopathic pulmonary
fibrosis
Pembrolizumab and nivolumab - CORRECT ANSWER - PD-1 inhibitors; immunotherapy
for certain malignancies
Treatment for anal cancer - CORRECT ANSWER - Irradiation and chemo, NOT surgery.
Chemo with mitomycin and 5-FU or capecitabine
What cancers utilize PET in preop staging? - CORRECT ANSWER - Gastroesophageal
cancers, SCLC. Some head and neck
Cisplatin - CORRECT ANSWER - Adjuvant chemo drug of choice for NSCLC (stage II
and III), usually paired with another agent (vinorelbine, pemetrexed, gemcitabine, or docetaxel)
Chemo choice for SCLC - CORRECT ANSWER - Cisplatin and Etoposide
Test results for primary adrenal insufficiency - CORRECT ANSWER - Low AM cortisol,
high ACTH
Danazol - CORRECT ANSWER - The only FDA-approved med for cyclic breast pain.
Rarely used because of bad side effects such as hirsutism, amenorrhea
Entecavir - CORRECT ANSWER - Antiviral used to treat Hep B