q
Lehne’s Pharmacotherapeutics for Advanced Practice Nurses
q q q q q
and Physician Assistants
q q q
Laura D. Rosenthal, and Jacqueline Rosenjack Burchum
q q q q q q
2nd Edition
q
,Table of Contents
q q
Unit q01 qIntroduction 1
Unit q02 qBasic qPrinciples qof qPharmacology 6
Unit q03 qDrug qTherapy qAcross qthe qLife qSpan 15
Unit q04 qPeripheral qNervous qSystem qDrugs 22
Unit q05 qCentral qNervous qSystem qDrugs 31
Unit q06 qDrugs qfor qPain 38
Unit q07 qPsychotherapeutic qDrugs 43
Unit q08 qSubstance qUse qDisorders 51
Unit q09 qDrugs qThat qAffect qthe qHeart, qBlood qVessels, qBlood, qand qBlood qVolume 59
Unit q10 qDrugs qfor qEndocrine qDisorders 68
Unit q11 qWomen’s qHealth 73
Unit q12 qMen’s qHealth 78
Unit q13 qAntiinflammatory, qAntiallergic, qand qImmunologic qDrugs 83
Unit q14 qDrugs qfor qBone qand qJoint qDisorders 91
Unit q15 qRespiratory qTract qDrugs 97
Unit q16 qGastrointestinal qDrugs 102
Unit q17 qNutrition qand qComplimentary qTherapies 110
Unit q18 qTherapy qof qInfectious qand qParasitic qDiseases 116
Unit q19 qCancer qTherapy 140
Unit q20 qDrugs qfor qEyes, qEars, qand qSkin 145
Unit q21 qDrugs qTherapy qin qAcute qCare 152
,Test qBank q- qLehne’s qPharmacotherapeutics qfor qAdvanced qPractice qNurses q& qPhysician qAssistants, q2e
q(Rosenthal, q2021)
Unit q01: qIntroduction
Rosenthal: qLehne's qPharmacotherapeutics qfor qAdvanced qPractice qNurses qand qPhysician
qAssistants, q2nd qEdition
MULTIPLE qCHOICE
1. A qpatient qdiagnosed qwith qchronic qpain qcalls qto qrequest qan qoxycodone q(Oxycontin)
qrefill. qWhich qaction qshould qthe qprescriber qtake qinitially?
a. Fax qthe qrenewal qorder qto qthe qpharmacy.
b. Arrange qto qschedule qan qappointment qwith qthe qpatient.
c. Verify qthe qpatient’s qadherence qto qthe qprescribed qdrug qregimen.
d. Determine qthe qpatient’s qcurrent qmedication qdosage qand qpain qlevel.
ANS: q q B
Schedule qII qmedications qare qnot qeligible qfor qrefills, qand qprescriptions qmust qbe
qhandwritten. qIt qis qimportant qto qverify qthe qpatient’s qadherence qto qthe qdrug qregimen qand
qdetermine qthe qcurrent qdosage qof qmedication qand qpain qlevel; qhowever, qthis qcan qbe
qaccomplished qby qscheduling qan qappointment qand qevaluating qthe qpatient qin qperson.
2. A qmetered-dose qalbuterol qinhaler qis qprescribed qfor qasthma qmanagement. qThe qpatient
qreports qfeeling qjittery qsometimes qwhen qtaking qthe qmedication, qand qdoes qnot qfeel qthat qthe
qmedication qis qalways qeffective. qWhich qaction qwill qthe qprovider qtake qto qbest qminimize
qpatient qrisks qand qmaximize qmedication qeffectiveness?
a. Ask qthe qpatient qto qdemonstrate quse qof qthe qinhaler qand qassess qeffectiveness.
b. Assess qthe qpatient’s qexposure qto qfirst- qand qsecond-hand qtobacco qsmoke.
c. Auscultate qthe qpatient's ql u n W
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in qother qrelevant qvital qsigns.
d. Decrease qthe qdosage qto qreduce qside qeffects.
ANS: q q C
Assessing qand qevaluating qlung qsounds qas qwell qas qother qvital qsigns qhelps qdetermine qthe
qpatient's qphysical qresponse qto qthe qmedication qand qallows qcomparison qto qthe qpatient's
qbaseline qvital qsigns. qAsking qthe qpatient qto qdemonstrate qinhaler quse qhelps qto qevaluate qthe
qpatient’s qability qto qadminister qthe qmedication qproperly qand qis qpart qof qan qeffective
qevaluation, qbut qis qnot qa qpriority qintervention qbased qon qthe qpatient’s qcurrent qreport.
qAssessing qtobacco qsmoke qexposure qhelps qdetermine qwhether qnondrug qtherapies, qsuch qas
qsmoke qavoidance, qcan qbe qused qas qan qadjunct qto qdrug qtherapy, qbut qdoes qnot qrelate qto qthe
qpatient’s qcurrent qproblem. qRewriting qthe qprescription qto qdecrease qthe qdosage qmay
qaddress qthe qdegree qof qjitteriness qexperienced, qbut qdoes qnot qaddress qthe qpatient’s qconcern
qthat qthe qdrug qis qnot qalways qeffective.
3. A qpatient qis qprescribed qmetronidazole qfor qbacterial qvaginosis. qWhich qpatient qhistory
qfinding qwould qbe qmost qconcerning qto qthe qprovider?
a. The qpatient qhad qa qrecent qyeast qinfection.
b. There qis qa qfamily qhistory qof qcervical qcancer.
c. The qpatient qdrinks qtwo qglasses qof qwine qevery qnight.
d. The qpatient qis
unemployed. qANS:
q q C
1 q| qP qa qg qe
, Test qBank q- qLehne’s qPharmacotherapeutics qfor qAdvanced qPractice qNurses q& qPhysician qAssistants, q2e
q(Rosenthal, q2021)
Patients qtaking qmetronidazole qshould qbe qeducated qnot qto qdrink qalcohol qto qprevent qa
qdisulfiram-like qreaction. qIt qwould qbe qconcerning qthat qthe qpatient qdrinks qwine qdaily.
qHistory q of qa qyeast qinfection qmay qindicate qincreased qrisk qfor qrecurrence qwith
qadministration qof qan qantimicrobial. qA qfamily qhistory qof qcervical qcancer qis qnot qrelated qto
qadministration qof qmetronidazole. qUnemployment qcan qindicate qlack qof qinsurance qcoverage,
qwhich qmay qlimit qthe qpatient’s qability qto qpurchase qmedications; qhowever, qgeneric
qmetronidazole qis qone qof qthe qless qexpensive qmedications.
4. The qprovider qprepares qa qpatient qwith qnewly qdiagnosed qtype q1 qdiabetes qfor qhospital
qdischarge. qWhich qaction qby qthe qprovider qwill qbest qsupport qthe qpatient’s qability qto
qeffectively qmanage qmedication qtherapy?
a. Asking qthe qpatient qto qdemonstrate qhow qto qmeasure qand qadminister qinsulin
b. Discussing qmethods qof qstoring qinsulin qand qdiscarding qsyringes
c. Giving qinformation qabout qhow qdiet qand qexercise qaffect qinsulin qrequirements
d. Teaching qthe qpatient qabout qthe qlong-term qconsequences qof qpoor qdiabetes qcontrol
ANS: q q A
Because qinsulin qmust qbe qgiven qcorrectly qto qcontrol qsymptoms qand qprevent qan qoverdose,
qit qis qmost qimportant qfor qthe qpatient qto qknow qhow qto qmeasure qand qadminister qit. qAsking
qfor qa qdemonstration qof qtechnique qis qthe qbest qway qto qdetermine qwhether qthe qpatient qhas
qunderstood qthe qteaching. qThe qother qteaching qpoints qare qimportant qas qwell, qbut qthey qare
qnot qas qcritical.
5. A qpatient qreports qthat qa qmedication qprescribed qfor qrecurrent qmigraine qheadaches qis
qnot qworking. qWhich qaction qis qthe qprescriber’s qpriority qwhen qaddressing qthe qpatient's
qconcern?
a. Ask qthe qpatient qabout qthe qnumber qand qfrequency qof qtablets qtaken.
b. Assess qthe qpatient’s qheadache qpain qon qa qscale qfrom q1 qto q10.
c. Prescribe q a q new q medicationWfW
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d. Suggest qbiofeedback qas qan qadjunct qto qdrug qtherapy.
ANS: q q A
When qevaluating qthe qeffectiveness qof qa qdrug, qit qis qimportant qto qdetermine qhow qoften qthe
qpatient qis qusing qthe qdrug. qAsking qthe qpatient qto qidentify qhow qmany qtablets qare qtaken qand
qhow qoften qhelps qthe qprovider qdetermine qeffective qdosages qand qadherence qto qthe
qmedication qregimen. qThe qpatient qhas qalready qstated qthat qthe qmedication qis qnot qworking;
qthe qactual qlevel qof qpain qmay qdetermine qthe qdegree qto qwhich qit qis qnot qworking, qbut qit
qdoes qnot qhelp qthe qprovider qto qdetermine qwhy qit qis qnot qworking. qThe qassessment qprocess
qshould qgather qas qmuch qinformation qabout qcompliance, qsymptoms, qand qdrug
qeffectiveness qas qpossible qbefore qenacting qa qchange qin qtreatment. qBiofeedback qmay qbe qan
qeffective qadjunct qto qtreatment, qbut qit qshould qnot qbe qrecommended qwithout qcomplete
qinformation qabout qdrug qeffectiveness.
6. The qdrug qmanual qstates qthat qolder qadult qpatients qare qat qincreased qrisk qfor qhepatotoxicity.
qWhich qaction qis qmost qimportant qwhen qprescribing qthis qmedication qto qan q80-year-old
qpatient?
a. Obtaining qbaseline qliver qfunction qstudies
b. Ensuring qthat qthe qdrug qis qtaken qin qthe qcorrect qdose qat qthe qcorrect qtime
c. Discontinuing qthe qorder; qthe qdrug qis qcontraindicated qfor qthis qpatient
d. Giving qthe qmedication qintravenously qto qavoid qfirst qpass
metabolism qANS:
q q A
2 q| qP qa qg qe