,TEST BANK FOR
q q
Immunology qand qSerology qin qLaboratory qMedicine, q7th qEdition qby qMary qLouise qTurgeon
Chapter q1-27
Chapter q01: qHighlights qof qthe qInnate qand qAdaptive qImmune qSystems
MULTIPLE qCHOICE
1. The q―father‖ qof qimmunology qis qgenerally qconsidered qto qbe
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: q B
Louis qPasteur qis qgenerally qconsidered qto qbe qthe q―father qof qimmunology.‖
DIF: Cognitive qLevel: qI
2. An qearly qform qof qimmunization qwas qpracticed qby qthe
a. Romans.
b. Greeks.
c. Chinese.
d. Native qAmericans.
ANS: q C
Beginning qabout q1000 qAD, qthe qChinese qpracticed qa qform qof qimmunization qby qinhaling qdried
qpowders qderived qfrom qthe qcrusts qof qsmallpox qlesions.
DIF: Cognitive qLevel: qI
3. A qspecific qfunction qof qthe qimmune qsystem qis qto
a. recognize qself qfrom qnonself.
b. defend qthe qbody qagainst qnonself.
c. amplify qspecific qfunctions.
d. Both qA qand qB.
ANS: q D
The qfunction qof qthe qimmune qsystem qis qto qrecognize qself qfrom qnonself qand qdefend qthe qbody
qagainst qnonself. qSuch qa qsystem qis qnecessary qfor qsurvival. qThe qimmune qsystem qalso qhas
qnonspecific qeffector qmechanisms qthat qusually qamplify qthe qspecific qfunctions. qNonspecific
qcomponents qof qthe qimmune qsystem qinclude qmononuclear qphagocytes, qpolymorphonuclear
qleukocytes, qand qsoluble qfactors q(e.g., qcomplement).
DIF: Cognitive qLevel: qI
4. An qundesirable qconsequence qof qimmunity qis
a. natural qresistance.
b. acquired qresistance qto qinfectious qdiseases.
, c. an qautoimmune qdisorder.
d. recovery qfrom qinfectious qdisease.
ANS: q C
The qdesirable qconsequences qof qimmunity qinclude qnatural qresistance, qrecovery, qand qacquired
qresistance qto qinfectious qdiseases. qA qdeficiency qor qdysfunction qof qthe qimmune qsystem qcan
qcause qmany qdisorders. qUndesirable qconsequences qof qimmunity qinclude qallergy, qrejection qof
qa qtransplanted qorgan, qor qan qautoimmune qdisorder.
DIF: Cognitive qLevel: qI
5. The qimmune qsystem qhas qvarious qdistinctive qcharacteristics qexcept;
a. specificity.
b. memory.
c. mobility.
d. noncooperation qamong qdifferent qcells.
ANS: q D
The qimmune qsystem qis qcomposed qof qa qlarge, qcomplex qset qof qwidely qdistributed qelements,
qwith qthe qdistinctive qcharacteristics qof qspecificity, qmemory, qmobility, qreplicability, qand
qcooperation qamong qdifferent qcells qor qcellular qproducts. qSpecificity qand qmemory qare
qcharacteristics qof qlymphocytes qin qthe qimmune qsystem. qNonspecific qelements qof qthe qimmune
qsystem qdemonstrate qmobility. qIn qaddition, qspecific qand qnonspecific qcellular qcomponents qof
qthe qimmune qsystem qcan qreplicate. qCooperation qis qrequired qfor qoptimal qfunctioning, qand
qinteraction qinvolves qspecific qcellular qelements, qcell qproducts, qand qnonlymphoid qelements.
DIF: Cognitive qLevel: qI
6. Hematopoiesis qoccurs qin qthe qyolk qsac qduring qthe
a. immediate qhours qafter qconception
b. second qmonth qof qgestation.
c. second qtrimester qof qgestation.
d. periods qof qsevere qanemia qin qchildren.
ANS: q A
The qsites qof qblood qcell qdevelopment, qor qhematopoiesis, qfollow qa qdefinite qsequence qin qthe
qembryo qand qfetus. qHematopoiesis qoccurs qin qthe qyolk qsac qduring qthe qsecond qmonth qof
qgestation.
DIF: Cognitive qLevel: qII
7. The qsequence qof qblood qcell qdevelopment qin qthe qembryo qand qfetus qis
a. yolk qsac, qliver-spleen, qbone qmarrow.
b. yolk qsac, qbone qmarrow, qliver/spleen.
c. liver-spleen, qyolk qsac, qbone qmarrow.
d. bone qmarrow, qliver-spleen, qyolk qsac.
ANS: q A
, The qfirst qblood qcells qare qprimitive qred qblood qcells q(erythroblasts; qRBCs) qformed qin qthe
qislets qof qthe qyolk qsac qduring qthe qfirst q2 qto q8 qweeks qof qlife. qGradually, qthe qliver qand qspleen
qreplace qthe qyolk qsac qas qthe qsites qof qblood qcell qdevelopment. qBy qthe qsecond qmonth qof
qgestation, qthe qliver qbecomes qthe qmajor qsite qof qhematopoiesis, qand qgranular qtypes qof
qleukocytes qhave qmade qtheir qinitial qappearance. qThe qliver qand qspleen qpredominate qfrom
qabout q2 qto q5 qmonths qof qfetal qlife. qIn qthe qfourth qmonth qof qgestation, qbone qmarrow qbegins
qto qproduce qblood qcells. qAfter qthe qfifth qfetal qmonth, qbone qmarrow qbegins qto qassume qits
qultimate qrole qas qthe qprimary qsite qof qhematopoiesis.
DIF: Cognitive qLevel: qII
8. The qprimary qfunction qof qmature qneutrophils qis
a. to qreduce qinflammation.
b. to qlyse qparasites qin qthe qcirculatory qsystem.
c. antigen qrecognition.
d. phagocytosis.
ANS: q D
Various qphagocytic qcells qcontinually qcirculate qthroughout qthe qblood, qlymph, qgastrointestinal
qsystem, qand qrespiratory qtract. qWhen qtrauma qoccurs, qthe qneutrophils qarrive qat qthe qsite qof
qinjury qand qcan qbe qfound qin qthe qinitial qexudate qin qless qthan q1 qhour. qMonocytes qare qslower
qin qmoving qto qthe qinflammatory qsite. qMacrophages qresident qin qthe qtissues qof qthe qbody qare
qalready qin qplace qto qdeal qwith qan qintruding qagent. qAdditional qmacrophages qfrom qthe qbone
qmarrow qand qother qtissues qcan qbe qreleased qin qsevere qinfections.
DIF: Cognitive qLevel: qII
9. Primary qgranules, qor qazurophilic qgranules, qin qneutrophils qcontain
a. lysozyme.
b. myeloperoxidase.
c. lactoferrin.
d. Both qA qand qB.
ANS: q D
Granules qin qthe qphagocyte qcytosol qcontain qdegradatory qenzymes qof qthree qtypes
1. Primary, qor qazurophilic, qgranules qcontaining qenzymes q(e.g.,
qlysozyme, qmyeloperoxidase)
2. Secondary, qor qspecific, qgranules qcontaining qsubstances qsuch qas qlactoferrin.
3. Tertiary qgranules qcontaining qsubstances qsuch qas qcaspases
DIF: Cognitive qLevel: qI
10. The qorigin qof qa qcondition qwhen qeosinophils qare qincreased qin qthe qcirculating qblood qis
qassociated qwith:
a. fungus
b. parasitic qamoeba
c. allergic qreactions
d. bacteria
ANS: q C
q q
Immunology qand qSerology qin qLaboratory qMedicine, q7th qEdition qby qMary qLouise qTurgeon
Chapter q1-27
Chapter q01: qHighlights qof qthe qInnate qand qAdaptive qImmune qSystems
MULTIPLE qCHOICE
1. The q―father‖ qof qimmunology qis qgenerally qconsidered qto qbe
a. Koch.
b. Pasteur.
c. Gram.
d. Salk.
ANS: q B
Louis qPasteur qis qgenerally qconsidered qto qbe qthe q―father qof qimmunology.‖
DIF: Cognitive qLevel: qI
2. An qearly qform qof qimmunization qwas qpracticed qby qthe
a. Romans.
b. Greeks.
c. Chinese.
d. Native qAmericans.
ANS: q C
Beginning qabout q1000 qAD, qthe qChinese qpracticed qa qform qof qimmunization qby qinhaling qdried
qpowders qderived qfrom qthe qcrusts qof qsmallpox qlesions.
DIF: Cognitive qLevel: qI
3. A qspecific qfunction qof qthe qimmune qsystem qis qto
a. recognize qself qfrom qnonself.
b. defend qthe qbody qagainst qnonself.
c. amplify qspecific qfunctions.
d. Both qA qand qB.
ANS: q D
The qfunction qof qthe qimmune qsystem qis qto qrecognize qself qfrom qnonself qand qdefend qthe qbody
qagainst qnonself. qSuch qa qsystem qis qnecessary qfor qsurvival. qThe qimmune qsystem qalso qhas
qnonspecific qeffector qmechanisms qthat qusually qamplify qthe qspecific qfunctions. qNonspecific
qcomponents qof qthe qimmune qsystem qinclude qmononuclear qphagocytes, qpolymorphonuclear
qleukocytes, qand qsoluble qfactors q(e.g., qcomplement).
DIF: Cognitive qLevel: qI
4. An qundesirable qconsequence qof qimmunity qis
a. natural qresistance.
b. acquired qresistance qto qinfectious qdiseases.
, c. an qautoimmune qdisorder.
d. recovery qfrom qinfectious qdisease.
ANS: q C
The qdesirable qconsequences qof qimmunity qinclude qnatural qresistance, qrecovery, qand qacquired
qresistance qto qinfectious qdiseases. qA qdeficiency qor qdysfunction qof qthe qimmune qsystem qcan
qcause qmany qdisorders. qUndesirable qconsequences qof qimmunity qinclude qallergy, qrejection qof
qa qtransplanted qorgan, qor qan qautoimmune qdisorder.
DIF: Cognitive qLevel: qI
5. The qimmune qsystem qhas qvarious qdistinctive qcharacteristics qexcept;
a. specificity.
b. memory.
c. mobility.
d. noncooperation qamong qdifferent qcells.
ANS: q D
The qimmune qsystem qis qcomposed qof qa qlarge, qcomplex qset qof qwidely qdistributed qelements,
qwith qthe qdistinctive qcharacteristics qof qspecificity, qmemory, qmobility, qreplicability, qand
qcooperation qamong qdifferent qcells qor qcellular qproducts. qSpecificity qand qmemory qare
qcharacteristics qof qlymphocytes qin qthe qimmune qsystem. qNonspecific qelements qof qthe qimmune
qsystem qdemonstrate qmobility. qIn qaddition, qspecific qand qnonspecific qcellular qcomponents qof
qthe qimmune qsystem qcan qreplicate. qCooperation qis qrequired qfor qoptimal qfunctioning, qand
qinteraction qinvolves qspecific qcellular qelements, qcell qproducts, qand qnonlymphoid qelements.
DIF: Cognitive qLevel: qI
6. Hematopoiesis qoccurs qin qthe qyolk qsac qduring qthe
a. immediate qhours qafter qconception
b. second qmonth qof qgestation.
c. second qtrimester qof qgestation.
d. periods qof qsevere qanemia qin qchildren.
ANS: q A
The qsites qof qblood qcell qdevelopment, qor qhematopoiesis, qfollow qa qdefinite qsequence qin qthe
qembryo qand qfetus. qHematopoiesis qoccurs qin qthe qyolk qsac qduring qthe qsecond qmonth qof
qgestation.
DIF: Cognitive qLevel: qII
7. The qsequence qof qblood qcell qdevelopment qin qthe qembryo qand qfetus qis
a. yolk qsac, qliver-spleen, qbone qmarrow.
b. yolk qsac, qbone qmarrow, qliver/spleen.
c. liver-spleen, qyolk qsac, qbone qmarrow.
d. bone qmarrow, qliver-spleen, qyolk qsac.
ANS: q A
, The qfirst qblood qcells qare qprimitive qred qblood qcells q(erythroblasts; qRBCs) qformed qin qthe
qislets qof qthe qyolk qsac qduring qthe qfirst q2 qto q8 qweeks qof qlife. qGradually, qthe qliver qand qspleen
qreplace qthe qyolk qsac qas qthe qsites qof qblood qcell qdevelopment. qBy qthe qsecond qmonth qof
qgestation, qthe qliver qbecomes qthe qmajor qsite qof qhematopoiesis, qand qgranular qtypes qof
qleukocytes qhave qmade qtheir qinitial qappearance. qThe qliver qand qspleen qpredominate qfrom
qabout q2 qto q5 qmonths qof qfetal qlife. qIn qthe qfourth qmonth qof qgestation, qbone qmarrow qbegins
qto qproduce qblood qcells. qAfter qthe qfifth qfetal qmonth, qbone qmarrow qbegins qto qassume qits
qultimate qrole qas qthe qprimary qsite qof qhematopoiesis.
DIF: Cognitive qLevel: qII
8. The qprimary qfunction qof qmature qneutrophils qis
a. to qreduce qinflammation.
b. to qlyse qparasites qin qthe qcirculatory qsystem.
c. antigen qrecognition.
d. phagocytosis.
ANS: q D
Various qphagocytic qcells qcontinually qcirculate qthroughout qthe qblood, qlymph, qgastrointestinal
qsystem, qand qrespiratory qtract. qWhen qtrauma qoccurs, qthe qneutrophils qarrive qat qthe qsite qof
qinjury qand qcan qbe qfound qin qthe qinitial qexudate qin qless qthan q1 qhour. qMonocytes qare qslower
qin qmoving qto qthe qinflammatory qsite. qMacrophages qresident qin qthe qtissues qof qthe qbody qare
qalready qin qplace qto qdeal qwith qan qintruding qagent. qAdditional qmacrophages qfrom qthe qbone
qmarrow qand qother qtissues qcan qbe qreleased qin qsevere qinfections.
DIF: Cognitive qLevel: qII
9. Primary qgranules, qor qazurophilic qgranules, qin qneutrophils qcontain
a. lysozyme.
b. myeloperoxidase.
c. lactoferrin.
d. Both qA qand qB.
ANS: q D
Granules qin qthe qphagocyte qcytosol qcontain qdegradatory qenzymes qof qthree qtypes
1. Primary, qor qazurophilic, qgranules qcontaining qenzymes q(e.g.,
qlysozyme, qmyeloperoxidase)
2. Secondary, qor qspecific, qgranules qcontaining qsubstances qsuch qas qlactoferrin.
3. Tertiary qgranules qcontaining qsubstances qsuch qas qcaspases
DIF: Cognitive qLevel: qI
10. The qorigin qof qa qcondition qwhen qeosinophils qare qincreased qin qthe qcirculating qblood qis
qassociated qwith:
a. fungus
b. parasitic qamoeba
c. allergic qreactions
d. bacteria
ANS: q C
