Pharmacology

Antiadrenergicgheffects EPS Sedationgh NMS Antipsychotics:ghDrugghInteractionsgh-ghcorrectghanswers-Decreasedghantipsychoticgheffectsghw/ghamphetamines Increasedghsedation,ghdecreasedghlevels,ghhypotensionghw/ghbarbiturates,ghBZAs,ghnarcotics Decreasedghlevelsghw/ghsmoking Decreasedgheffectivenessghw/ghhypoglycemics Decreasedghantiparkinsongheffectsghw/ghlevodopa,ghincreasesghpsychosis MoodghStabilizers:ghMOAgh-ghcorrectghanswers-Blocksghvoltage-sensitiveghNaghchannelsgh IncreasesghGABA MoodghStabilizers:ghSideghEffectsgh-ghcorrectghanswers-Tremorgh Lethargy Malaise Anorexia N/V/D Edema Abdominalghpain CNSghs/s Weightghgain Hairghloss Impairedghthyroidghfunction VPA-ghhepatotoxicity,ghpancreatitis,ghthrombocytopenia,ghDRESSgh Lithium-ghnephrotoxicity,ghCVD MoodghStabilizers:ghPregnancygh&ghLactationgh-ghcorrectghanswers-VPA-ghneuralghtube Lithium-ghEbsteinghanomaly Benzodiazepinesgh(BZAs):ghMOAgh-ghcorrectghanswers-BindsghtoghBZAghreceptorsghatghGABAaghligand-gatedghClghchannelghtoghenhanceghinhibitorygheffectsghofghGABAghinghamygdala-centeredghfearghcircuitsgh BoostsghCl Benzodiazepinesgh(BZAs):ghSideghEffectsgh-ghcorrectghanswers-Amnesia Ataxia,ghmotorghincoordination Confusion,ghimpairedghcognitiongh Depression Drowsiness,ghdizziness,ghlightheadedness Dysarthria Headache Weightghgaingh Sexualghdysfunction Benzodiazepinesgh(BZAs):ghDrugghInteractionsgh-ghcorrectghanswers-IncreasedghsedationghwithghCNSghdepressants,ghMAOIs,ghTCAsgh IncreasedghBZAghlevelsghw/ghdisulfiram,ghcimetidinegh Increasedghphenytoinghlevels Decreasedgheffectivenessghw/ghantacids DecreasedghNMghblockageghw/ghsuccinylcholine Benzodiazepinesgh(BZAs):ghPregnancygh&ghLactationgh-ghcorrectghanswers-Floppyghinfantghsyndrome Stimulants:ghMOAgh-ghcorrectghanswers-InhibitghreuptakeghofghDAghandghNEghtoghincreaseghlevels Stimulants:ghSideghEffectsgh-ghcorrectghanswers-Anorexia,ghweightghloss Nausea Insomnia,ghnightmares Dizziness Reboundghphenomenagh Irritability,ghdysphoria,ghagitation,ghmoodiness Growthghandghweightghsuppression Stimulants:ghDrugghInteractionsgh-ghcorrectghanswers-IncreasedghCVgheffectsghwithghsympathetics,ghMAOIs,ghalsoghdecreasedgheffectiveness Increasedghlevelsghw/ghTCAz,ghwarfarin,ghprimidone,ghphenobarbital,ghphenytoin,ghphenylbutazone Non-Stimulant:ghMOAgh-ghcorrectghanswers-SelectiveghinhibitionghofghpresynapticghNETghtoghenhanceghNEghinghtheghsynapse Non-Stimulant:ghSideghEffectsgh-ghcorrectghanswers-Abdominalghdiscomfort Decreasedghappetite,ghweightghloss Sexualghdysfunction Dizziness,ghvertigo Irritability,ghmoodghswings Severeghliverghinjury Non-Stimulant:ghDrugghInteractionsgh-ghcorrectghanswers-2D6ghinhgh(SSRIs,ghWellbutrin)ghincreasesghlevels