Test Bank For Clayton's Basic Pharmacology for Nurses 19th Edition By Bruce Clayton, Michelle Willihnganz, Samuel Gurevitz ( ) / 9780323796309 / Chapter 1-48 / Complete Questions and Answers A+

Test Bank For Clayton’s Basic Pharmacology for Nurses 19th EditionB
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y Michelle J. Willihnganz, Samuel L. Gurevitz, Bruce Clayton Compl
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ete

,Chapter 01: Drug Definitions, Standards, and Information Sources Willihnga
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nz: Clayton’s Basic Pharmacology for Nurses, 19th Edition
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MULTIPLE CHOICE wl




1. Which name identifies a drug listed by the US Food a
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ndDrug Administration (FDA)?
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a. Brand
b. Nonproprietary
c. Official
d. Trademark
ANS: C wl


The official name is the name under which a drug is liste
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d by the FDA. The brand name, or trademark, is the name
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given to a drug by its manufacturer. The nonproprietary,
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or generic, name is provided by the United States Adopted
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Names Council.
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DIF: Cognitive Level: Knowledge REF: p. 9 wl wl wl wl


OBJ: 1NAT: NCLEX Client Needs Category: Safe, Effective C
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areEnvironment TOP: Nursing Process Step: Assessment
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CON: wl


Patient Education wl




2. Which source contains information specific to nutritional supplements?
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a. USP Dictionary of USAN & International Drug Names
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b. Natural Medicines Comprehensive Database wl wl wl


c. United States Pharmacopoeia/National Formulary (USP NF)
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d. Drug Interaction Facts wl wl




ANS: C wl


United States Pharmacopoeia/National Formulary contains information specific to nutritiona
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lsupplements. USP Dictionary of USAN & International Drug Names is a compilation of d
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rugnames, pronunciation guide, and possible future FDA approved drugs; it does not inclu
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de nutritional supplements. Natural Medicines Comprehensive Database contains
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evidence-
based information on herbal medicines and herbal combination products; it does notinclude i
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nformation specific to nutritional supplements. Drug Interaction Facts contains comprehen
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sive information on drug interaction facts; it does not include nutritional supplements.
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DIF: Cognitive Level: Knowledge REF: p. 4 wl wl w l wl


OBJ: 3NAT: NCLEX Client Needs Category: Physiological Int
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egrity
TOP: Nursing Process Step: Assessment CON: Nutrition | Patient Education
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3. Which drug reference contains drug monographs that describe all drugs in a therapeutic class?
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a. Drug Facts and Comparisons wl wl wl

,Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Editi
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on
b. Drug Interaction Facts wl wl


c. Handbook on Injectable Drugs wl wl wl


d. Martindale—The Complete Drug Reference wl wl wl




ANS: A wl


Drug Facts and Comparisons contains drug monographs that describe all drugs in
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atherapeutic class. Monographs are formatted as tables to allow comparison of simil
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arproducts, brand names, manufacturers, cost indices, and available dosage forms
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Online version is available. wl wl wl




DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 wl wl w l wl wl wl


OBJ: 3 wlwlw lNAT: NCLEX Client Needs Category: Physiological Integrity wl wl wl wl wl wl


TOP: Nursing Process Step: Assessment CON: Safety | Patient Education | Clinical Judgment
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4. Which drug reference contains monographs about virtually every single-
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entity drug availablein the United States and describes therapeutic uses of drugs, includin
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g approved and unapproved uses?
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a. Martindale: The Complete Drug Reference wl wl wl wl


b. AHFS Drug Information wl wl


c. Drug Reference wl


d. Drug Facts and Comparisons wl wl wl




ANS: B wl


AHFS Drug Information contains monographs about virtually every single-
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entity drug available in the United States and describes therapeutic uses of drugs, including
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approved andunapproved uses. wl lw wl




DIF: Cognitive Level: Knowledge REF: p. 4 Table 1.2 wl wl w l wl wl wl


OBJ: 3 wlwlw lNAT: NCLEX Client Needs Category: Physiological Integrity wl wl wl wl wl wl


TOP: Nursing Process Step: Planning
w l CON: Safety | Patient Education | Clinical Judgment
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5. Which online drug reference makes available to healthcare providers and the public a s
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tandard, comprehensive, up-to-date look up and downloadable resource about medicines?
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a. American Drug Index wl wl


b. American Hospital Formulary wl wl


c. DailyMed
d. Drug Reference wl




ANS: C wl


DailyMed makes available to healthcare providers and the public a standard, comprehensiv
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e,up-to-
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date look up and downloadable resource about medicines. The American Drug Index isnot
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appropriate for patient use. The American Hospital Formulary is not appropriate for patie
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nt use. The drug reference is not appropriate for patient use.
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DIF: Cognitive Level: Knowledge REF: p. 3 | p. 4 wl wl w l wl wl wl wl


OBJ: 3NAT: NCLEX Client Needs Category: Physiological Int
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egrity
TOP: Nursing Process Step: Implementation
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CON: Safety | Patient Education | Clinical Judgment
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6. Which legislation authorizes the FDA to determine the safety of a drug before its marketing?
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a. Federal Food, Drug, and Cosmetic Act (1938) wl wl wl wl wl wl


b. Durham Humphrey Amendment (1952) wl wl wl

, Test Bank For Clayton’s Basic Pharmacology for Nurses 19th Editi
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on
c. Controlled Substances Act (1970) wl wl wl


d. Kefauver Harris Drug Amendment (1962) wl wl wl wl




ANS: A wl


The Federal Food, Drug, and Cosmetic Act of 1938 authorized the FDA to determine the s
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afety of all drugs before marketing. Later amendments and acts helped tighten FDA contro
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l and ensure drug safety. The Durham Humphrey Amendment defines the kinds of drugs t
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hat cannot be used safely without medical supervision and restricts their sale to prescriptio
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n by a licensed practitioner. The Controlled Substances Act addresses only controlled subst
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ances andtheir categorization. The Kefauver Harris Drug Amendment ensures drug efficacy
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and greaterdrug safety. Drug manufacturers are required to prove to the FDA the effective
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ness of their products before marketing them.
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DIF: Cognitive Level: Knowledge REF: p. 5 Table l.3 wl wl wl wl wl wl


OBJ: 5 w l


NAT: NCLEX Client Needs Category: Physiological Integrit wl wl wl wl wl wl


yTOP: Nursing Process Step: Assessment
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CON: Safety | Patient Education | Evidence | Health Care Law
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7. Which classification does meperidine (Demerol) fall under?
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a. I
b. II
c. III
d. IV
ANS: B wl


Meperidine (Demerol) is a Schedule II drug; it has a high potential for abuse and may lea
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d tosevere psychological and physical dependence. Schedule I drugs have high potential for
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abuseand no recognized medical use. Schedule III drugs have some potential for abuse. Us
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e may lead to low to moderate physical dependence or high psychological dependence. Sc
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hedule IVdrugs have low potential for abuse. Use may lead to limited physical or psychol
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ogical dependence. wl




DIF: Cognitive Level: Knowledge REF: p. 10 wl wl w l wl


OBJ: 2NAT: NCLEX Client Needs Category: Safe, Effective C
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are Environment
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TOP: Nursing Process Step: Assessment CON: Patient Education | Addiction | Pain
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8. Which action would the FDA take to expedite drug development and approval for an outbre
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akof smallpox?
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a. List smallpox as a health orphan disease.
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b. Omit the preclinical research phase. wl wl wl wl


c. Extend the clinical research phase. wl wl wl wl


d. Fast track the investigational drug.
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ANS: D wl


Once the Investigational New Drug Application has been approved, the drug can receive h
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ighest priority within the agency, which is called fast tracking. A smallpox outbreak would
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become a priority concern in the world. Orphan diseases are not researched in a priority
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manner. Preclinical research is not omitted. Extending any phase of the research would me
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ana longer time to develop a vaccine. The FDA must ensure that all phases of the preclinical
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andclinical research phase have been completed in a safe manner.
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DIF: Cognitive Level: Knowledge wl wl REF: wlwlwl p. 7 wl OBJ: 5 wl