Genetics BIO351 Tests #3 2025
Questions and Answers 100% Pass
The step in DNA replication in which the replication proteins open up the double helix
and prepare for complementary base pairing is called - ✔✔Initiation
The protein that progressively unwinds DNA ahead of each replication fork is called: -
✔✔Helicase
Assume that a wild-type sequence is 5'AGCCTAC3'. Indicate the sequence that might
be produced by a transversion - ✔✔5'ATCCTAC3'
Assume that the mutation rate for a given gene is 5´10-6 mutations per gene per
generation. For that gene how many mutations would be expected if 10 million sperm
are examined? - ✔✔50
The hydrolysis of a purine base from the deoxyribose-phosphate backbone is called: -
✔✔Depurination
The bacterial repair system that corrects mismatched bases after polymerization is able
to discriminate between the old and newly made DNA strands because: - ✔✔Older
DNA contains methyl groups at specific sequences
Which interaction listed below is exclusively involved in maintaining tertiary structure
in protein molecules. - ✔✔Covalent Bond, Hydrogen Bond, Hydrophobic/Hydrophilic
Interactions, Ionic Interactions
Though sickle-cell anemia is frequently lethal for individuals who are homozygous for
the sickle cell allele, natural selection seems to have maintained that allele in certain
COPYRIGHT © 2025 BY SOPHIA BENNETT, ALL RIGHTS RESERVED 1
, geographic locations. A likely explanation for this observation is: - ✔✔individuals who
are heterozygous for the sickle-cell allele are protected from malaria.
The term fecundity refers to: - ✔✔ability to produce offspring.
How many DIFFERENT amino acids could be coded for using the synthetic mRNA
sequence of (5' UGCUGCUGC 3')? - ✔✔3
The sequences within mRNA that are spliced out (removed) are called: - ✔✔Introns
Aminoacyl-tRNA Synthetase is the enzyme that: - ✔✔Adds the appropriate amino acid
to an uncharged tRNA
A mutation that is characterized by a change in the DNA sequence, but no change in the
resulting protein sequence, is called a: - ✔✔Silent Mutation
Protein synthesis begins with the amino acid ___________, as its codon is the one used
as the "start codon" by nearly all organisms. - ✔✔Methionine
In Sanger (enzymatic extension) sequencing, what causes DNA synthesis to terminate at
a specific base? - ✔✔Nucleotide triphosphates that lack a hydroxyl.
A genomic library is: - ✔✔collection of DNA fragments from an organism, inserted into
vectors.
Where do restriction enzymes come from, and what is their normal physiological
function? - ✔✔Bacteria produce them to protect against viral invasion.
FISH analysis is useful for: - ✔✔Fluorescent in situ hybridization
Random generation of overlapping insert fragments from large clones for the purpose
of sequence analysis is termed: - ✔✔Shotgun
Noncoding RNAs include: - ✔✔tRNAs, snRNAs, rRNAs, snoRNAs
COPYRIGHT © 2025 BY SOPHIA BENNETT, ALL RIGHTS RESERVED 2
Questions and Answers 100% Pass
The step in DNA replication in which the replication proteins open up the double helix
and prepare for complementary base pairing is called - ✔✔Initiation
The protein that progressively unwinds DNA ahead of each replication fork is called: -
✔✔Helicase
Assume that a wild-type sequence is 5'AGCCTAC3'. Indicate the sequence that might
be produced by a transversion - ✔✔5'ATCCTAC3'
Assume that the mutation rate for a given gene is 5´10-6 mutations per gene per
generation. For that gene how many mutations would be expected if 10 million sperm
are examined? - ✔✔50
The hydrolysis of a purine base from the deoxyribose-phosphate backbone is called: -
✔✔Depurination
The bacterial repair system that corrects mismatched bases after polymerization is able
to discriminate between the old and newly made DNA strands because: - ✔✔Older
DNA contains methyl groups at specific sequences
Which interaction listed below is exclusively involved in maintaining tertiary structure
in protein molecules. - ✔✔Covalent Bond, Hydrogen Bond, Hydrophobic/Hydrophilic
Interactions, Ionic Interactions
Though sickle-cell anemia is frequently lethal for individuals who are homozygous for
the sickle cell allele, natural selection seems to have maintained that allele in certain
COPYRIGHT © 2025 BY SOPHIA BENNETT, ALL RIGHTS RESERVED 1
, geographic locations. A likely explanation for this observation is: - ✔✔individuals who
are heterozygous for the sickle-cell allele are protected from malaria.
The term fecundity refers to: - ✔✔ability to produce offspring.
How many DIFFERENT amino acids could be coded for using the synthetic mRNA
sequence of (5' UGCUGCUGC 3')? - ✔✔3
The sequences within mRNA that are spliced out (removed) are called: - ✔✔Introns
Aminoacyl-tRNA Synthetase is the enzyme that: - ✔✔Adds the appropriate amino acid
to an uncharged tRNA
A mutation that is characterized by a change in the DNA sequence, but no change in the
resulting protein sequence, is called a: - ✔✔Silent Mutation
Protein synthesis begins with the amino acid ___________, as its codon is the one used
as the "start codon" by nearly all organisms. - ✔✔Methionine
In Sanger (enzymatic extension) sequencing, what causes DNA synthesis to terminate at
a specific base? - ✔✔Nucleotide triphosphates that lack a hydroxyl.
A genomic library is: - ✔✔collection of DNA fragments from an organism, inserted into
vectors.
Where do restriction enzymes come from, and what is their normal physiological
function? - ✔✔Bacteria produce them to protect against viral invasion.
FISH analysis is useful for: - ✔✔Fluorescent in situ hybridization
Random generation of overlapping insert fragments from large clones for the purpose
of sequence analysis is termed: - ✔✔Shotgun
Noncoding RNAs include: - ✔✔tRNAs, snRNAs, rRNAs, snoRNAs
COPYRIGHT © 2025 BY SOPHIA BENNETT, ALL RIGHTS RESERVED 2
