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Genetics Essentials: Concepts and Connections 5th Edition by
W W W W W W W
Benjamin A. Pierce
W W
www.PlusBay.Plus
,TABLE OF CONTENT
W W
ChapterW01:W IntroductionW toW Genetics .................................................................................................................... 3
ChapterW 02:W ChromosomesW andW CellularW Reproduction ...................................................................................... 15
ChapterW 03:W BasicW PrinciplesW ofW Heredity ........................................................................................................... 32
ChapterW 04:W ExtensionsW andW ModificationsW ofW BasicW Principles ........................................................................ 59
ChapterW05:W Linkage,W Recombination,W andW EukaryoticW GeneW Mapping ............................................................ 98
ChapterW 06:W ChromosomeW Variation .................................................................................................................. 115
ChapterW07:W BacterialW andW ViralW GeneticW Systems ........................................................................................... 139
ChapterW 08W DNA:W TheW ChemicalW NatureW ofW theW Gene .................................................................................... 152
ChapterW 09:W DNAW ReplicationW andW Recombination .......................................................................................... 181
ChapterW10:W FromW DNAW toW Proteins:W TranscriptionW andW RNAW Processing ..................................................... 198
ChapterW11:W FromW DNAW toW Proteins:W Translation ............................................................................................. 224
ChapterW 12:W ControlW ofW GeneW Expression.......................................................................................................... 244
ChapterW13:W GeneW Mutations,W TransposableW Elements,W andW DNAW Repair ...................................................... 278
ChapterW14:W MolecularW GeneticW AnalysisW andW Biotechnology.......................................................................... 298
ChapterW 15:W GenomicsW andW Proteomics ............................................................................................................. 314
ChapterW 16:W CancerW Genetics ............................................................................................................................. 332
ChapterW 17:W QuantitativeW Genetics ..................................................................................................................... 346
ChapterW 18:W PopulationW andW EvolutionaryW Genetics ......................................................................................... 366
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,ChapterW01:WIntroductionWtoWGenetics
1. AlbinismWisWrareWinWmostWhumanWpopulations,WoccurringWatWaWfrequencyWofWaboutW1WinW20,000Wpeople.WHo
weveW r,WtheWtraitWoccursWatWaWfrequencyWofW1WinW200WinWcertainWHopiWvillagesWofWBlackWMesaWinWArizona.WE
xplainWinWterW msWofWnaturalWselectionWwhyWalbinismWisWsoWrareWinWmostWhumanWpopulations.
ANSWER:WInWmostWpopulations,WthereWisWfairlyWstrongWselectionWagainstWalbinismWbecauseWalbinosWdon’tWprod
uceWmelanin,WcausingWtheirWskinWcellsWnotWtoWbeWprotectedWfromWtheWdamagingWeffectsWofWsunlight.
WAlso,WtW heWlackWofWmelaninWinWtheirWeyesWcausesWthemWtoWhaveWpoorWeyesight.WFinally,WinWmostWc
ulturesWalbinW osWareWseenWasWabnormal,WandWtheyWareWnotWnormallyWsoughtWoutWforWmarriageWandW
mating.WTherefore,WinWmostWpopulationsWtheWallelesWthatWcauseWalbinismWareWselectedWagainst,WandW
theyWdecreaseWinWfrequWencyWorWareWkeptWatWaWlowWlevel,WcausingWtheWrecessiveWtraitWtoWbeWrare.
2. AlbinismWisWrareWinWmostWhumanWpopulations,WoccurringWatWaWfrequencyWofWaboutW1WinW20,000Wpeople.WHo
weveW r,WtheWtraitWoccursWatWaWfrequencyWofW1WinW200WinWcertainWHopiWvillagesWofWBlackWMesaWinWArizona.WE
xplainWinWterW msWofWnaturalWselectionW whyWtheWtraitW isWsoWmuchW moreWcommonWamongWtheWHopisWofWBlackW
Mesa.
ANSWER:WAlbinosWoccupyWaWprivilegedWpositionWamongWtheWHopisWofWBlackWMesa.WInWthisWculture,Walbino
sWaW reWviewedWasWespeciallyWpretty,Wclean,WandWintelligent,WandWtheyWoftenWoccupyWpositionsWof
WleadersWhip.WAlbinosWareWcelebratedWinWtheWvillagesWasW aWsignW ofWpurityWofWHopiWbloodWinWthe
Wcommunity.
Furthermore,WalbinosWareWoftenWexcusedWfromWnormalWmaleWfieldWlaborWbecauseWofWtheirWsensitivit
yWtoWsunlight,WcausingWthemWtoWbeWleftWbehindWinWtheWvillageWwithWtheWwomenWduringWtheWdaytime
.WThisWaWllowsWthemWextraWmatingWopportunitiesWcomparedWtoWtheWotherWmenWofWtheWvillage.WThere
fore,WtheWallWelesWthatWcauseWalbinismWareWeitherWselectedWforWinWthisWcultureWorWatWleastWnotWselect
edWagainstWasWstroWnglyWasWinWotherWcultures,WallowingWtheWtraitWtoWoccurWatWaWmuchWhigherWfreque
ncy.
3. WhichWoneWofWtheWfollowingWpairingsWbetweenWtheWsubdisciplineWofWgeneticsWandWtheWphenome
nonWisWINCORRECT?
a. evolution—populationW genetics
b. geneW regulation—molecularW genetics
c. allelicW frequencyW alteration—populationW genetics
d. arrangementW ofW genesW onW chromosome—transmissionW genetics
e. chemicalW natureW ofW theWgene—transmissionW genetics
ANSWER:We
4. WhichW oneW ofW theW followingW topicsW ofW researchW belongsW toW theW disciplineW ofW transmissionWgenetics?
a. inheritanceW patternW ofW geneW alleles
b. mechanismW ofW DNAW replication
c. geneW expressionW patterns
d. evolution
e. chemicalW modificationW ofW nucleicW acids
ANSWER:Wa
5. TheW completeW geneticW makeupW ofW anW organismW isW referredW toW asW its
a. chromosome.
b. alleles.
www.PlusBay.Plus
, c. locus.
www.PlusBay.Plus
Genetics Essentials: Concepts and Connections 5th Edition by
W W W W W W W
Benjamin A. Pierce
W W
www.PlusBay.Plus
,TABLE OF CONTENT
W W
ChapterW01:W IntroductionW toW Genetics .................................................................................................................... 3
ChapterW 02:W ChromosomesW andW CellularW Reproduction ...................................................................................... 15
ChapterW 03:W BasicW PrinciplesW ofW Heredity ........................................................................................................... 32
ChapterW 04:W ExtensionsW andW ModificationsW ofW BasicW Principles ........................................................................ 59
ChapterW05:W Linkage,W Recombination,W andW EukaryoticW GeneW Mapping ............................................................ 98
ChapterW 06:W ChromosomeW Variation .................................................................................................................. 115
ChapterW07:W BacterialW andW ViralW GeneticW Systems ........................................................................................... 139
ChapterW 08W DNA:W TheW ChemicalW NatureW ofW theW Gene .................................................................................... 152
ChapterW 09:W DNAW ReplicationW andW Recombination .......................................................................................... 181
ChapterW10:W FromW DNAW toW Proteins:W TranscriptionW andW RNAW Processing ..................................................... 198
ChapterW11:W FromW DNAW toW Proteins:W Translation ............................................................................................. 224
ChapterW 12:W ControlW ofW GeneW Expression.......................................................................................................... 244
ChapterW13:W GeneW Mutations,W TransposableW Elements,W andW DNAW Repair ...................................................... 278
ChapterW14:W MolecularW GeneticW AnalysisW andW Biotechnology.......................................................................... 298
ChapterW 15:W GenomicsW andW Proteomics ............................................................................................................. 314
ChapterW 16:W CancerW Genetics ............................................................................................................................. 332
ChapterW 17:W QuantitativeW Genetics ..................................................................................................................... 346
ChapterW 18:W PopulationW andW EvolutionaryW Genetics ......................................................................................... 366
www.PlusBay.Plus
,ChapterW01:WIntroductionWtoWGenetics
1. AlbinismWisWrareWinWmostWhumanWpopulations,WoccurringWatWaWfrequencyWofWaboutW1WinW20,000Wpeople.WHo
weveW r,WtheWtraitWoccursWatWaWfrequencyWofW1WinW200WinWcertainWHopiWvillagesWofWBlackWMesaWinWArizona.WE
xplainWinWterW msWofWnaturalWselectionWwhyWalbinismWisWsoWrareWinWmostWhumanWpopulations.
ANSWER:WInWmostWpopulations,WthereWisWfairlyWstrongWselectionWagainstWalbinismWbecauseWalbinosWdon’tWprod
uceWmelanin,WcausingWtheirWskinWcellsWnotWtoWbeWprotectedWfromWtheWdamagingWeffectsWofWsunlight.
WAlso,WtW heWlackWofWmelaninWinWtheirWeyesWcausesWthemWtoWhaveWpoorWeyesight.WFinally,WinWmostWc
ulturesWalbinW osWareWseenWasWabnormal,WandWtheyWareWnotWnormallyWsoughtWoutWforWmarriageWandW
mating.WTherefore,WinWmostWpopulationsWtheWallelesWthatWcauseWalbinismWareWselectedWagainst,WandW
theyWdecreaseWinWfrequWencyWorWareWkeptWatWaWlowWlevel,WcausingWtheWrecessiveWtraitWtoWbeWrare.
2. AlbinismWisWrareWinWmostWhumanWpopulations,WoccurringWatWaWfrequencyWofWaboutW1WinW20,000Wpeople.WHo
weveW r,WtheWtraitWoccursWatWaWfrequencyWofW1WinW200WinWcertainWHopiWvillagesWofWBlackWMesaWinWArizona.WE
xplainWinWterW msWofWnaturalWselectionW whyWtheWtraitW isWsoWmuchW moreWcommonWamongWtheWHopisWofWBlackW
Mesa.
ANSWER:WAlbinosWoccupyWaWprivilegedWpositionWamongWtheWHopisWofWBlackWMesa.WInWthisWculture,Walbino
sWaW reWviewedWasWespeciallyWpretty,Wclean,WandWintelligent,WandWtheyWoftenWoccupyWpositionsWof
WleadersWhip.WAlbinosWareWcelebratedWinWtheWvillagesWasW aWsignW ofWpurityWofWHopiWbloodWinWthe
Wcommunity.
Furthermore,WalbinosWareWoftenWexcusedWfromWnormalWmaleWfieldWlaborWbecauseWofWtheirWsensitivit
yWtoWsunlight,WcausingWthemWtoWbeWleftWbehindWinWtheWvillageWwithWtheWwomenWduringWtheWdaytime
.WThisWaWllowsWthemWextraWmatingWopportunitiesWcomparedWtoWtheWotherWmenWofWtheWvillage.WThere
fore,WtheWallWelesWthatWcauseWalbinismWareWeitherWselectedWforWinWthisWcultureWorWatWleastWnotWselect
edWagainstWasWstroWnglyWasWinWotherWcultures,WallowingWtheWtraitWtoWoccurWatWaWmuchWhigherWfreque
ncy.
3. WhichWoneWofWtheWfollowingWpairingsWbetweenWtheWsubdisciplineWofWgeneticsWandWtheWphenome
nonWisWINCORRECT?
a. evolution—populationW genetics
b. geneW regulation—molecularW genetics
c. allelicW frequencyW alteration—populationW genetics
d. arrangementW ofW genesW onW chromosome—transmissionW genetics
e. chemicalW natureW ofW theWgene—transmissionW genetics
ANSWER:We
4. WhichW oneW ofW theW followingW topicsW ofW researchW belongsW toW theW disciplineW ofW transmissionWgenetics?
a. inheritanceW patternW ofW geneW alleles
b. mechanismW ofW DNAW replication
c. geneW expressionW patterns
d. evolution
e. chemicalW modificationW ofW nucleicW acids
ANSWER:Wa
5. TheW completeW geneticW makeupW ofW anW organismW isW referredW toW asW its
a. chromosome.
b. alleles.
www.PlusBay.Plus
, c. locus.
www.PlusBay.Plus