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NAGELHOUT PHARM 1 - EXAM 1 2025| BRAND NEW
ACTUAL EXAM WITH 100% VERIFIED QUESTIONS AND
CORRECT SOLUTIONS| GUARANTEED VALUE PACK| ACE
YOUR GRADES.
Pharmacokinetics - correct answer - The study of absorption,
distribution, metabolism and excretion of drugs. What the person
does to the drug.
Pharmacodynamics - correct answer - Physiological and
biochemical mechanism of action of drugs. What the drug does to
the person.
Ligands - correct answer - Chemical substances that bind to a
specific receptor site (endogenous or exogenous)
Agonist - correct answer - Stimulates the function that receptor
serves
Antagonist - correct answer - Blocks the function that receptor
serves
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Competitive binding - correct answer - Reversible, wears off
Noncompetitve binding - correct answer - Non-reversible (i.e.
ASA)
Therapeutic index - correct answer - LD50/ED50; measure of
safety, higher numbers = safer
LD50 - correct answer - Lethal dose in 50% of the population
ED50 - correct answer - Effective dose in 50% of population
ED99 - correct answer - Effective dose in 99% of population
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Therapeutic range - correct answer - A measure of blood levels
with drug use. A range of at least ED99 and less than toxic
threshold.
Bioavailability - correct answer - The % of a drug contained in a
drug product that enters the systemic circulation in an unchanged
for after administration of the product
Interaction - correct answer - Alteration in therapeutic action of a
drug by concurrent administration of other exogenous chemicals
Addition - correct answer - Combined effect of 2 drugs is equal to
the expected addition of their individual action (1+1=2)
Synergism - correct answer - Combined effect of 2 drugs is
greater than the expected addition of their individual action
(1+1=3)
Potentiation - correct answer - One drug's effect is enhanced by a
completely unrelated drug. 1+0=3
NAGELHOUT PHARM 1 - EXAM 1 2025| BRAND NEW
ACTUAL EXAM WITH 100% VERIFIED QUESTIONS AND
CORRECT SOLUTIONS| GUARANTEED VALUE PACK| ACE
YOUR GRADES.
Pharmacokinetics - correct answer - The study of absorption,
distribution, metabolism and excretion of drugs. What the person
does to the drug.
Pharmacodynamics - correct answer - Physiological and
biochemical mechanism of action of drugs. What the drug does to
the person.
Ligands - correct answer - Chemical substances that bind to a
specific receptor site (endogenous or exogenous)
Agonist - correct answer - Stimulates the function that receptor
serves
Antagonist - correct answer - Blocks the function that receptor
serves
, Page | 2
Competitive binding - correct answer - Reversible, wears off
Noncompetitve binding - correct answer - Non-reversible (i.e.
ASA)
Therapeutic index - correct answer - LD50/ED50; measure of
safety, higher numbers = safer
LD50 - correct answer - Lethal dose in 50% of the population
ED50 - correct answer - Effective dose in 50% of population
ED99 - correct answer - Effective dose in 99% of population
, Page | 3
Therapeutic range - correct answer - A measure of blood levels
with drug use. A range of at least ED99 and less than toxic
threshold.
Bioavailability - correct answer - The % of a drug contained in a
drug product that enters the systemic circulation in an unchanged
for after administration of the product
Interaction - correct answer - Alteration in therapeutic action of a
drug by concurrent administration of other exogenous chemicals
Addition - correct answer - Combined effect of 2 drugs is equal to
the expected addition of their individual action (1+1=2)
Synergism - correct answer - Combined effect of 2 drugs is
greater than the expected addition of their individual action
(1+1=3)
Potentiation - correct answer - One drug's effect is enhanced by a
completely unrelated drug. 1+0=3
