Evolutionary Analysis 5th Edition by Herron Jon; Freeman Scott ISBN 9780321998378
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Chapter 1-20
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Chapter 1 no n o n o A Case for Evolutionary Thinking: Understanding HIV
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1) In which of the following regions has AIDS killed the largest number of individuals?
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A) India
B) Sub-Saharan Africa no
C) United States no
D) China
E) UnitedKingdom no
Answer: B
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nSection: 1.1
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Skill: Knowledge/Comprehension
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2) The HIV virus contains all of the following components except
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A) integrase
B) double-stranded RNA no
C) single-stranded RNA no
D) reverse transcriptase no
E) protease
Answer: B
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Section:
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n 1.1 o
Skill: Knowledge/Comprehension
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3) The acronym HIV stands for which of the following?
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A) human intercellular virus no no
B) human immune virus no no
C) human immunodeficiency virus no no
D) human immunity virus no no
E) humanimmunodeficiencyvector no no
Answer: C
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Section: 1.1 n o
Skill: Knowledge/Comprehension
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4) Which of the following enzymes is responsible for transcribing viral RNA into DNA?
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A) RNA polymerase no
B) reverse transcriptase no
C) DNA polymerase no
D) reverse integrase no
E) RNAduplicase no
Answer: B
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Section: 1.1
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Skill: Knowledge/Comprehension
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Copyright © 2014 Pearson Education, Inc.
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,5) The proteins that enable the HIV virus to bind to cells are typically CD4 and CCR5. On what
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type of cells are these proteins typically observed?
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A) plasma cells no
B) dendritic cells no
C) effector helper T cells no no no
D) memory helper T cells no no no
E) both C and D no no no
Answer: E
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Section: 1.1
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Skill: Knowledge/Comprehension
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6) The AIDS phase of HIV infection begins when the concentration of CD4 T cells in the blood
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drops below what concentration?
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A) 2,000 cells per cubic millimeter no no no no
B) 1,000 cells per cubic millimeter no no no no
C) 500 cells per cubic millimeter
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D) 200 cells per cubic millimeter
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E) No CD4 T cells are observed.
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Answer: D
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Section: 1.1 n o
Skill: Knowledge/Comprehension
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7) Which of the following drug categories are used to treat HIV infections?
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A) integrase inhibitors no
B) protease inhibitors no
C) reverse transcriptase inhibitors no no
D) DNAse inhibitors no
E) fusion inhibitors no
Answer: D
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Section: 1.2
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Skill: Knowledge/Comprehension
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8) Coreceptor inhibitors block HIV infection by preventing which of the following? no no no no no no no no no no
A) binding of the HIV virion onto the plasma membrane no no no no no no no no
B) binding of the HIV virion onto the CCR5 receptor no no no no no no no no
C) binding of the HIV virion onto the gp120 protein no no no no no no no no
D) degrading the coreceptor so the virion cannot attach no no no no no no no
E) binding of the HIV virion onto the CD4 receptor no no no no no no no no
Answer: B
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Section: 1.2 n o
Skill: Application/Analysis
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9) What is the effect of the ∆32 allele of CCR5 on HIV binding?
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A) appears on the surface of CD4 T cells, but the HIV virion is unable to infect the host cell
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B) does not appear on the surface of CD4 T cells
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C) appears on the surface of the CD4 T cells and inactivates the virion upon binding
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D) interferes with binding of the virion to the CD4 receptor protein no no no no no no no no no no
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Copyright © 2014 Pearson Education, Inc. no no no no no
,E) appears on the surface of the CD4 T cells and causes the virion to lyse upon binding
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Answer: B
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Section: 1.3 n o
Skill: Application/Analysis
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10) The ∆32 allele of CCR5 is found at the highest frequency in which of the following
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populations?
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A) Africans
B) Japanese
C) North Americans no
D) Europeans
E) South Americans no
Answer: D
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n Section: 1.3
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Skill: Knowledge/Comprehension
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11) HIV-1 is believed to have been transmitted to humans from which of the following
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organisms?
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A) gorillas
B) sooty mangabeys no
C) African green monkeys no no
D) chimpanzees
E) baboons
Answer: D
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Section:
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n1.4 o
Skill: Knowledge/Comprehension
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12) HIV-1 Group M is responsible for 95% of human infections. When is it estimated that HIV-1
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Group M was transferred to humans?
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A) 1980
B) 1960
C) 1930
D) 1995
E) 1900
Answer: C n o
Section:
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Skill: Knowledge/Comprehension
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13) Antibodies and killer T cells recognize HIV or HIV-infected cells by binding to short pieces of
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viral proteins displayed on the virus or the infected host cell. These short pieces of viral proteins
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are called
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A) coat proteins no
B) virosomes
C) proteosomes
D) epitopes
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, E) episomes
Answer:
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