, Test Bank Qi
to accompany
Qi
Psychopharmacology, Third Edition Qi Qi
Meyer • Quenzer Qi Qi
Chapter 1: Principles of Pharmacology Qi Qi Qi Qi
Multiple Choice Qi
1. refer(s) to specific molecular changes that occur when a drug binds to a
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
particular target site or receptor, while
Qi Qi Qi Qi Qi
are the resulting widespread alterations in function.
Qi Qi Qi Qi Qi Qi
a. Drug action; therapeutic effects
Qi Qi Qi
b. Side effects; drug effects
Qi Qi Qi
c. Therapeutic effects; side effects Qi Qi Qi
d. Drug action; drug effects
Qi Qi Qi
Answer: d Qi
Textbook Reference: Pharmacology: The Science of Drug Action
Qi Qi Qi Qi Qi Qi Qi
2. After drug administration has occurred, the amount of drug in the blood that is free
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
to bind at specific target sites is referred to as
Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. the therapeutic dose.
Qi Qi
b. first-pass effects. Qi
c. bioavailability.
d. ED50.
Answer: c Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
3. The specific molecular changes that occur when a drug binds to a particular target si
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
te or receptor are referred to as
Qi Qi Qi Qi Qi Qi
a. drug effects.
Qi
b. drug action.
Qi
c. side effects.
Qi
d. placebo effects. Qi
Answer: b Qi
Textbook Reference: Pharmacology: The Science of Drug Action
Qi Qi Qi Qi Qi Qi Qi
4. Which of the following is not a possible explanation for placebo effects?
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. Pavlovian conditioning Qi
b. Genetic variation Qi
c. Drug competition
Qi
d. Expectation of outcome Qi Qi
Answer: c Qi
Textbook Reference: Pharmacology: The Science of Drug Action
Qi Qi Qi Qi Qi Qi Qi
Page 1 of 247
Qi Qi Qi
,5. The administration of oxytocin has been proposed as a treatment for autism. Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
6. Which factor does not affect the pharmacokinetics of a drug?
Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. Route of administration
Qi Qi
b. Lipid solubility
Qi
c. Depot binding Qi
d. Drug action Qi
Answer: d Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
7. First-pass metabolism occurs when drugs are taken
Qi Qi Qi Qi Qi Qi
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
8. The area postrema is one area in the brain where the
Qi Qi is not complete.
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. cerebrospinal fluid Qi
b. blood–brain barrier Qi
c. choroid plexus Qi
d. phospholipid membrane Qi
Answer: b Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
9. First-pass metabolism occurs with orally administered drugs because
Qi Qi Qi Qi Qi Qi Qi
a. their absorption is slowed by food.
Qi Qi Qi Qi Qi
b. drugs absorbed into the bloodstream from the stomach go to the liver on the way
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
to general circulation.
Qi Qi Qi
c. drugs must first survive the acidic environment of the stomach.
Qi Qi Qi Qi Qi Qi Qi Qi Qi
d. salivary enzymes in the mouth begin the process of metabolism.
Qi Qi Qi Qi Qi Qi Qi Qi Qi
Answer: b Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
10. Toxic substances in the blood trigger a vomiting response by activating the
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. blood–brain barrier. Qi
b. choroid plexus. Qi
c. area postrema.
Qi
d. median eminence. Qi
Page 2 of 247
Qi Qi Qi
, Answer: c Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
11. Drugs administered _ Qi have the most rapid onset of action. Qi Qi Qi Qi Qi Qi Qi
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
12. Ionization of a drug depends on the
Qi of the solution and the
Qi Qi Qi Qi Qi Qi Qi Qi Qi
of the drug.
Qi Qi
a. pH; pKa
Qi
b. pKa; pH Qi
c. concentration; lipid solubility Qi Qi
d. pH; concentration
Qi
Answer: a Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
13. The absorption of a drug depends on all of the following except
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. lipid solubility.
Qi
b. ionization.
c. body temperature.
Qi
d. the concentration of the drug.
Qi Qi Qi Qi
Answer: c Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
14. Drugs that are Qi should be avoided by women of childbearing age.
Qi Qi Qi Qi Qi Qi Qi Qi
a. teratogenic
b. able to cross the placental barrier
Qi Qi Qi Qi Qi
c. psychoactive
d. highly lipid-soluble
Qi
Answer: a Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
15. Agents that induce developmental abnormalities in a fetus are known as
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. psychoactive drugs. Qi
b. illicit drugs.
Qi
c. teratogens.
d. placental drugs. Qi
Answer: c Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
16. Depot binding is said to occur when drugs
Qi Qi Qi Qi Qi Qi Qi
a. bind to their target sites.
Qi Qi Qi Qi
Page 3 of 247
Qi Qi Qi
to accompany
Qi
Psychopharmacology, Third Edition Qi Qi
Meyer • Quenzer Qi Qi
Chapter 1: Principles of Pharmacology Qi Qi Qi Qi
Multiple Choice Qi
1. refer(s) to specific molecular changes that occur when a drug binds to a
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
particular target site or receptor, while
Qi Qi Qi Qi Qi
are the resulting widespread alterations in function.
Qi Qi Qi Qi Qi Qi
a. Drug action; therapeutic effects
Qi Qi Qi
b. Side effects; drug effects
Qi Qi Qi
c. Therapeutic effects; side effects Qi Qi Qi
d. Drug action; drug effects
Qi Qi Qi
Answer: d Qi
Textbook Reference: Pharmacology: The Science of Drug Action
Qi Qi Qi Qi Qi Qi Qi
2. After drug administration has occurred, the amount of drug in the blood that is free
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
to bind at specific target sites is referred to as
Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. the therapeutic dose.
Qi Qi
b. first-pass effects. Qi
c. bioavailability.
d. ED50.
Answer: c Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
3. The specific molecular changes that occur when a drug binds to a particular target si
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
te or receptor are referred to as
Qi Qi Qi Qi Qi Qi
a. drug effects.
Qi
b. drug action.
Qi
c. side effects.
Qi
d. placebo effects. Qi
Answer: b Qi
Textbook Reference: Pharmacology: The Science of Drug Action
Qi Qi Qi Qi Qi Qi Qi
4. Which of the following is not a possible explanation for placebo effects?
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. Pavlovian conditioning Qi
b. Genetic variation Qi
c. Drug competition
Qi
d. Expectation of outcome Qi Qi
Answer: c Qi
Textbook Reference: Pharmacology: The Science of Drug Action
Qi Qi Qi Qi Qi Qi Qi
Page 1 of 247
Qi Qi Qi
,5. The administration of oxytocin has been proposed as a treatment for autism. Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
6. Which factor does not affect the pharmacokinetics of a drug?
Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. Route of administration
Qi Qi
b. Lipid solubility
Qi
c. Depot binding Qi
d. Drug action Qi
Answer: d Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
7. First-pass metabolism occurs when drugs are taken
Qi Qi Qi Qi Qi Qi
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
8. The area postrema is one area in the brain where the
Qi Qi is not complete.
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. cerebrospinal fluid Qi
b. blood–brain barrier Qi
c. choroid plexus Qi
d. phospholipid membrane Qi
Answer: b Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
9. First-pass metabolism occurs with orally administered drugs because
Qi Qi Qi Qi Qi Qi Qi
a. their absorption is slowed by food.
Qi Qi Qi Qi Qi
b. drugs absorbed into the bloodstream from the stomach go to the liver on the way
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
to general circulation.
Qi Qi Qi
c. drugs must first survive the acidic environment of the stomach.
Qi Qi Qi Qi Qi Qi Qi Qi Qi
d. salivary enzymes in the mouth begin the process of metabolism.
Qi Qi Qi Qi Qi Qi Qi Qi Qi
Answer: b Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
10. Toxic substances in the blood trigger a vomiting response by activating the
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. blood–brain barrier. Qi
b. choroid plexus. Qi
c. area postrema.
Qi
d. median eminence. Qi
Page 2 of 247
Qi Qi Qi
, Answer: c Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
11. Drugs administered _ Qi have the most rapid onset of action. Qi Qi Qi Qi Qi Qi Qi
a. subcutaneously
b. intramuscularly
c. orally
d. intravenously
Answer: d Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
12. Ionization of a drug depends on the
Qi of the solution and the
Qi Qi Qi Qi Qi Qi Qi Qi Qi
of the drug.
Qi Qi
a. pH; pKa
Qi
b. pKa; pH Qi
c. concentration; lipid solubility Qi Qi
d. pH; concentration
Qi
Answer: a Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
13. The absorption of a drug depends on all of the following except
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. lipid solubility.
Qi
b. ionization.
c. body temperature.
Qi
d. the concentration of the drug.
Qi Qi Qi Qi
Answer: c Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
14. Drugs that are Qi should be avoided by women of childbearing age.
Qi Qi Qi Qi Qi Qi Qi Qi
a. teratogenic
b. able to cross the placental barrier
Qi Qi Qi Qi Qi
c. psychoactive
d. highly lipid-soluble
Qi
Answer: a Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
15. Agents that induce developmental abnormalities in a fetus are known as
Qi Qi Qi Qi Qi Qi Qi Qi Qi Qi
a. psychoactive drugs. Qi
b. illicit drugs.
Qi
c. teratogens.
d. placental drugs. Qi
Answer: c Qi
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
Qi Qi Qi Qi Qi Qi
16. Depot binding is said to occur when drugs
Qi Qi Qi Qi Qi Qi Qi
a. bind to their target sites.
Qi Qi Qi Qi
Page 3 of 247
Qi Qi Qi