,
, Test Bank r1
to accompany
r1
Psychopharmacology, 4th Edition r1 r1
Meyer • Quenzer r1 r1
Chapter 1: Principles of Pharmacology r1 r1 r1 r1
Multiple Choice r1
1. refer(s) to specific molecular changes that occur when a drug binds to a par1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
rticular target site or receptor, while
r1 r1 r1 r1 r1
are the resulting widespread alterations in function.
r1 r1 r1 r1 r1 r1
a. Drug action; therapeutic effects
r1 r1 r1
b. Side effects; drug effects
r1 r1 r1
c. Therapeutic effects; side effects r1 r1 r1
d. Drug action; drug effects
r1 r1 r1
Answer: d r1
Textbook Reference: Pharmacology: The Science of Drug Action
r1 r1 r1 r1 r1 r1 r1
2. After drug administration has occurred, the amount of drug in the blood that is free to
r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
bind at specific target sites is referred to as
r1 r1 r1 r1 r1 r1 r1 r1 r1
a. the therapeutic dose.
r1 r1
b. first-pass effects. r1
c. bioavailability.
d. ED50.
Answer: c r1
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
r1 r1 r1 r1 r1 r1
3. The specific molecular changes that occur when a drug binds to a particular target site
r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
or receptor are referred to as
r1 r1 r1 r1 r1 r1
a. drug effects. r1
b. drug action. r1
c. side effects.r1
d. placebo effects. r1
Answer: b r1
Textbook Reference: Pharmacology: The Science of Drug Action
r1 r1 r1 r1 r1 r1 r1
4. Which of the following is not a possible explanation for placebo effects?
r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
a. Pavlovian conditioning r1
b. Genetic variation r1
c. Drug competition r1
d. Expectation of outcome r1 r1
Answer: c r1
Textbook Reference: Pharmacology: The Science of Drug Action
r1 r1 r1 r1 r1 r1 r1
Page 1 of 247
r1 r1 r1
, 5. The administration of oxytocin has been proposed as a treatment for autism. r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c r1
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
r1 r1 r1 r1 r1 r1
6. Which factor does not affect the pharmacokinetics of a drug?
r1 r1 r1 r1 r1 r1 r1 r1 r1
a. Route of administration
r1 r1
b. Lipid solubility
r1
c. Depot binding r1
d. Drug action
r1
Answer: d r1
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
r1 r1 r1 r1 r1 r1
7. First-pass metabolism occurs when drugs are taken
r1 r1 r1 r1 r1 r1
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a r1
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
r1 r1 r1 r1 r1 r1
8. The area postrema is one area in the brain where the
r1 r1 is not complete.
r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
a. cerebrospinal fluid r1
b. blood–brain barrier r1
c. choroid plexus r1
d. phospholipid membrane r1
Answer: b r1
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
r1 r1 r1 r1 r1 r1
9. First-pass metabolism occurs with orally administered drugs because
r1 r1 r1 r1 r1 r1 r1
a. their absorption is slowed by food.
r1 r1 r1 r1 r1
b. drugs absorbed into the bloodstream from the stomach go to the liver on the way t
r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
o general circulation.
r1 r1
c. drugs must first survive the acidic environment of the stomach.
r1 r1 r1 r1 r1 r1 r1 r1 r1
d. salivary enzymes in the mouth begin the process of metabolism.
r1 r1 r1 r1 r1 r1 r1 r1 r1
Answer: b r1
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
r1 r1 r1 r1 r1 r1
10. Toxic substances in the blood trigger a vomiting response by activating the
r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
a. blood–brain barrier. r1
b. choroid plexus. r1
c. area postrema.
r1
d. median eminence. r1
Page 2 of 247
r1 r1 r1
, Test Bank r1
to accompany
r1
Psychopharmacology, 4th Edition r1 r1
Meyer • Quenzer r1 r1
Chapter 1: Principles of Pharmacology r1 r1 r1 r1
Multiple Choice r1
1. refer(s) to specific molecular changes that occur when a drug binds to a par1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
rticular target site or receptor, while
r1 r1 r1 r1 r1
are the resulting widespread alterations in function.
r1 r1 r1 r1 r1 r1
a. Drug action; therapeutic effects
r1 r1 r1
b. Side effects; drug effects
r1 r1 r1
c. Therapeutic effects; side effects r1 r1 r1
d. Drug action; drug effects
r1 r1 r1
Answer: d r1
Textbook Reference: Pharmacology: The Science of Drug Action
r1 r1 r1 r1 r1 r1 r1
2. After drug administration has occurred, the amount of drug in the blood that is free to
r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
bind at specific target sites is referred to as
r1 r1 r1 r1 r1 r1 r1 r1 r1
a. the therapeutic dose.
r1 r1
b. first-pass effects. r1
c. bioavailability.
d. ED50.
Answer: c r1
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
r1 r1 r1 r1 r1 r1
3. The specific molecular changes that occur when a drug binds to a particular target site
r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
or receptor are referred to as
r1 r1 r1 r1 r1 r1
a. drug effects. r1
b. drug action. r1
c. side effects.r1
d. placebo effects. r1
Answer: b r1
Textbook Reference: Pharmacology: The Science of Drug Action
r1 r1 r1 r1 r1 r1 r1
4. Which of the following is not a possible explanation for placebo effects?
r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
a. Pavlovian conditioning r1
b. Genetic variation r1
c. Drug competition r1
d. Expectation of outcome r1 r1
Answer: c r1
Textbook Reference: Pharmacology: The Science of Drug Action
r1 r1 r1 r1 r1 r1 r1
Page 1 of 247
r1 r1 r1
, 5. The administration of oxytocin has been proposed as a treatment for autism. r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
a. intravenous
b. oral
c. intranasal
d. intracerebral
Answer: c r1
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
r1 r1 r1 r1 r1 r1
6. Which factor does not affect the pharmacokinetics of a drug?
r1 r1 r1 r1 r1 r1 r1 r1 r1
a. Route of administration
r1 r1
b. Lipid solubility
r1
c. Depot binding r1
d. Drug action
r1
Answer: d r1
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
r1 r1 r1 r1 r1 r1
7. First-pass metabolism occurs when drugs are taken
r1 r1 r1 r1 r1 r1
a. orally.
b. intravenously.
c. subcutaneously.
d. nasally.
Answer: a r1
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
r1 r1 r1 r1 r1 r1
8. The area postrema is one area in the brain where the
r1 r1 is not complete.
r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
a. cerebrospinal fluid r1
b. blood–brain barrier r1
c. choroid plexus r1
d. phospholipid membrane r1
Answer: b r1
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
r1 r1 r1 r1 r1 r1
9. First-pass metabolism occurs with orally administered drugs because
r1 r1 r1 r1 r1 r1 r1
a. their absorption is slowed by food.
r1 r1 r1 r1 r1
b. drugs absorbed into the bloodstream from the stomach go to the liver on the way t
r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
o general circulation.
r1 r1
c. drugs must first survive the acidic environment of the stomach.
r1 r1 r1 r1 r1 r1 r1 r1 r1
d. salivary enzymes in the mouth begin the process of metabolism.
r1 r1 r1 r1 r1 r1 r1 r1 r1
Answer: b r1
Textbook Reference: Pharmacokinetic Factors Determining Drug Action
r1 r1 r1 r1 r1 r1
10. Toxic substances in the blood trigger a vomiting response by activating the
r1 r1 r1 r1 r1 r1 r1 r1 r1 r1 r1
a. blood–brain barrier. r1
b. choroid plexus. r1
c. area postrema.
r1
d. median eminence. r1
Page 2 of 247
r1 r1 r1
