APHON Principles of Chemo and Biotherapy
UPDATED Exam Questions and
CORRECT Answers
Biotherapy - CORRECT ANSWER - Targeted anticancer agents also known as biological
response modifiers (BRM)
Tyrosine kinase inhibitors (TKIs) are what class - CORRECT ANSWER - Biotherapy
Define pharmacokinetics - CORRECT ANSWER - Study of drug absorption, metabolism, and
excretion
Define pharmacodynamics - CORRECT ANSWER - The concentration of the drug in the
body and how it produces a response
Define adjuvant chemotherapy - CORRECT ANSWER - The use of chemo after another type
of therapy, such as surgery, to treat residual disease or undetectable metastasis.
Define neoadjuvant chemotherapy - CORRECT ANSWER - When chemo is used
preoperatively to decrease tumor burden in order to make it easier to remove the tumor
surgically.
Why use chemotherapy - CORRECT ANSWER - To prevent cancer cells from dividing,
metastasizing, and ultimately causing the death of the patient
What are chemotherapy effects on the cell cycle with cell cycle specific drugs? - CORRECT
ANSWER - 1. Greatest effect on actively dividing cells 2. NOT active in G0 phase 3. Greatest
action in divided doses or continuous infusion 4. Cytotoxic effects occur when cell repair or
division is attmepted
UPDATED Exam Questions and
CORRECT Answers
Biotherapy - CORRECT ANSWER - Targeted anticancer agents also known as biological
response modifiers (BRM)
Tyrosine kinase inhibitors (TKIs) are what class - CORRECT ANSWER - Biotherapy
Define pharmacokinetics - CORRECT ANSWER - Study of drug absorption, metabolism, and
excretion
Define pharmacodynamics - CORRECT ANSWER - The concentration of the drug in the
body and how it produces a response
Define adjuvant chemotherapy - CORRECT ANSWER - The use of chemo after another type
of therapy, such as surgery, to treat residual disease or undetectable metastasis.
Define neoadjuvant chemotherapy - CORRECT ANSWER - When chemo is used
preoperatively to decrease tumor burden in order to make it easier to remove the tumor
surgically.
Why use chemotherapy - CORRECT ANSWER - To prevent cancer cells from dividing,
metastasizing, and ultimately causing the death of the patient
What are chemotherapy effects on the cell cycle with cell cycle specific drugs? - CORRECT
ANSWER - 1. Greatest effect on actively dividing cells 2. NOT active in G0 phase 3. Greatest
action in divided doses or continuous infusion 4. Cytotoxic effects occur when cell repair or
division is attmepted
