CNPR EXAM QUESTIONS WITH
VERIFIED ANSWERS
Pro-drugs are administered in active form, which is metabolized into an inactive
form. - Answer-False
The kidney of an 85-year old person excretes drugs only ______ as efficiently as
that of a 35-year old person. - Answer-Around 50%
The normal age-related decrease in kidney function can help doctors determine an
appropriate dosage based solely on a person's age. - Answer-True
What differentiates a caplet from a tablet? - Answer-Caplets are shaped like
capsules and have film coatings to aid in swallowing.
Where will you find the legend, "Caution: Federal Law prohibits dispensing without a
prescription."? - Answer-On the label of all prescription drugs.
What happens in slow acetylators? - Answer-Drugs that are metabolized by N-acetyl
transferase tend to reach higher blood levels and remain the body longer.
About _______ of the people in the U.S. are slow acetylators. - Answer-50%
Drug-drug interactions are always harmful. - Answer-False
Smoking decreases the effectiveness of some drugs. - Answer-True
Because dietary supplements are not drugs, interactions with drugs are not a
concern. - Answer-False
Ehrlich stated that an ideal drug (magic bullet) does not exist, would be aimed
precisely at a disease site, and would not harm healthy tissues. - Answer-True
What is the difference between resistance and tolerance? - Answer-Tolerance refers
to a person's diminished response to a drug after repeated use, while resistance
applies to microorganism's or cancer cell's abilities to withstand drug effects.
Between 3% and 7% of hospital admissions in the U.S. are estimated to be for
treatment of adverse drug reactions. - Answer-True
There is no universal scale for quantifying the severity of an adverse drug reaction. -
Answer-True
Why is noncompliance a serious public health concern? - Answer-It increases the
cost of medical care.
,Name 3 items available for which patent protection is available under U.S.
regulations. - Answer-The drug itself, the method of delivering and releasing the drug
into the bloodstream, and the way the drug is made.
Drugs' trade names are often unrelated to their intended use. - Answer-False
Like foods and household products, generic drugs are usually lower quality than the
brand name drugs for which they are marketed as equivalents. - Answer-False
Legally, bioequivalence of different versions of a drug can vary by up to _____
percent. - Answer-20
Biologics do not cause immune responses. - Answer-False
"Large molecule" products are developed and manufactured by a chemical process.
- Answer-False
What are the drugs that attract or bind cell receptors in order to mimic or enhance
activities by endogenous chemical messengers? - Answer-Agonists
What term denotes how an API works in the body? - Answer-Mechanism of action.
What cements the active and inert components together to maintain cohesive
portions? - Answer-Binders.
What does the abbreviation BID denote? - Answer-Twice a day
What is the medical abbreviation for 'as needed'? - Answer-PRN.
Which components might cause patient's different reactions to brand name and
generic drugs? - Answer-Differences in inactive ingredients.
All cells have a nucleus. - Answer-False
Name three things that affect drug response. - Answer-The patient's genetic
makeup, age, body size, and use of other drugs and dietary supplements. The
patient's other conditions and diseases. Whether or not the patient takes the drug
properly.
What is a treatment group? - Answer-A group of patients assigned to receive a
specified treatment.
What is the main difference between a blinded and a double-blinded study? -
Answer-In a double blind study, neither the study staff nor the study participants
know which subjects are in the experimental group and which are in the control
group.
What does asymptomatic mean? - Answer-Not exhibiting signs or symptoms.
, What term denotes the study of bodily functions (as opposed to structures)? -
Answer-Physiology.
In its broadest definition, a drug is any substance that produces a physical or
psychological change in the body. - Answer-True
How does the Federal Food, Drug and Cosmetic Act (FFDCA) define a drug? -
Answer-Any substance intended for use in the diagnosis, cure, mitigation, treatment,
or prevention of disease, or a substance other than food intended to affect the
structure or function of the body.
Most of the body's required vitamins must be taken from outside the body. - Answer-
True
ADME testing measures the rate at which the body absorbs the drug, distributes it to
the organs necessary to produce the desired effect, metabolizes it into waste
material, and then excretes it from the body. - Answer-True
What field is ADME testing used in primarily? - Answer-Pharmacokinetics.
Placebo effects can lead to withdrawal symptoms. - Answer-True
On average, only about 5 of 4,000 drugs studied in laboratory are eventually studied
in people. - Answer-True
Sublingual drugs are absorbed directly and almost immediately into the bloodstream.
- Answer-True
What are 3 of the 7 rights of drug administration? - Answer-The right patient, the
right drug, the right dose.
Drug reactions are predictable because they do not occur after a person has been
previously exposed to the drug one or more times without any allergic reactions. -
Answer-False
What is the typical relationship between a drug's site of administration and site of
action? - Answer-They are usually somewhat removed from one another.
What is CMAX? - Answer-The peak plasma concentration on a measuring curve.
Pharmacoprocesses are a main concept of clinical pharmacology. - Answer-False
Which is not a route of drug administration - buccal, intramuscular, sublingual, or
transfugal? - Answer-Transfugal
How are intradermal drugs delivered? - Answer-By injection under the skin.
An injection of anesthetic directly into the bloodstream is an example of intravenous
drug delivery. - Answer-True
VERIFIED ANSWERS
Pro-drugs are administered in active form, which is metabolized into an inactive
form. - Answer-False
The kidney of an 85-year old person excretes drugs only ______ as efficiently as
that of a 35-year old person. - Answer-Around 50%
The normal age-related decrease in kidney function can help doctors determine an
appropriate dosage based solely on a person's age. - Answer-True
What differentiates a caplet from a tablet? - Answer-Caplets are shaped like
capsules and have film coatings to aid in swallowing.
Where will you find the legend, "Caution: Federal Law prohibits dispensing without a
prescription."? - Answer-On the label of all prescription drugs.
What happens in slow acetylators? - Answer-Drugs that are metabolized by N-acetyl
transferase tend to reach higher blood levels and remain the body longer.
About _______ of the people in the U.S. are slow acetylators. - Answer-50%
Drug-drug interactions are always harmful. - Answer-False
Smoking decreases the effectiveness of some drugs. - Answer-True
Because dietary supplements are not drugs, interactions with drugs are not a
concern. - Answer-False
Ehrlich stated that an ideal drug (magic bullet) does not exist, would be aimed
precisely at a disease site, and would not harm healthy tissues. - Answer-True
What is the difference between resistance and tolerance? - Answer-Tolerance refers
to a person's diminished response to a drug after repeated use, while resistance
applies to microorganism's or cancer cell's abilities to withstand drug effects.
Between 3% and 7% of hospital admissions in the U.S. are estimated to be for
treatment of adverse drug reactions. - Answer-True
There is no universal scale for quantifying the severity of an adverse drug reaction. -
Answer-True
Why is noncompliance a serious public health concern? - Answer-It increases the
cost of medical care.
,Name 3 items available for which patent protection is available under U.S.
regulations. - Answer-The drug itself, the method of delivering and releasing the drug
into the bloodstream, and the way the drug is made.
Drugs' trade names are often unrelated to their intended use. - Answer-False
Like foods and household products, generic drugs are usually lower quality than the
brand name drugs for which they are marketed as equivalents. - Answer-False
Legally, bioequivalence of different versions of a drug can vary by up to _____
percent. - Answer-20
Biologics do not cause immune responses. - Answer-False
"Large molecule" products are developed and manufactured by a chemical process.
- Answer-False
What are the drugs that attract or bind cell receptors in order to mimic or enhance
activities by endogenous chemical messengers? - Answer-Agonists
What term denotes how an API works in the body? - Answer-Mechanism of action.
What cements the active and inert components together to maintain cohesive
portions? - Answer-Binders.
What does the abbreviation BID denote? - Answer-Twice a day
What is the medical abbreviation for 'as needed'? - Answer-PRN.
Which components might cause patient's different reactions to brand name and
generic drugs? - Answer-Differences in inactive ingredients.
All cells have a nucleus. - Answer-False
Name three things that affect drug response. - Answer-The patient's genetic
makeup, age, body size, and use of other drugs and dietary supplements. The
patient's other conditions and diseases. Whether or not the patient takes the drug
properly.
What is a treatment group? - Answer-A group of patients assigned to receive a
specified treatment.
What is the main difference between a blinded and a double-blinded study? -
Answer-In a double blind study, neither the study staff nor the study participants
know which subjects are in the experimental group and which are in the control
group.
What does asymptomatic mean? - Answer-Not exhibiting signs or symptoms.
, What term denotes the study of bodily functions (as opposed to structures)? -
Answer-Physiology.
In its broadest definition, a drug is any substance that produces a physical or
psychological change in the body. - Answer-True
How does the Federal Food, Drug and Cosmetic Act (FFDCA) define a drug? -
Answer-Any substance intended for use in the diagnosis, cure, mitigation, treatment,
or prevention of disease, or a substance other than food intended to affect the
structure or function of the body.
Most of the body's required vitamins must be taken from outside the body. - Answer-
True
ADME testing measures the rate at which the body absorbs the drug, distributes it to
the organs necessary to produce the desired effect, metabolizes it into waste
material, and then excretes it from the body. - Answer-True
What field is ADME testing used in primarily? - Answer-Pharmacokinetics.
Placebo effects can lead to withdrawal symptoms. - Answer-True
On average, only about 5 of 4,000 drugs studied in laboratory are eventually studied
in people. - Answer-True
Sublingual drugs are absorbed directly and almost immediately into the bloodstream.
- Answer-True
What are 3 of the 7 rights of drug administration? - Answer-The right patient, the
right drug, the right dose.
Drug reactions are predictable because they do not occur after a person has been
previously exposed to the drug one or more times without any allergic reactions. -
Answer-False
What is the typical relationship between a drug's site of administration and site of
action? - Answer-They are usually somewhat removed from one another.
What is CMAX? - Answer-The peak plasma concentration on a measuring curve.
Pharmacoprocesses are a main concept of clinical pharmacology. - Answer-False
Which is not a route of drug administration - buccal, intramuscular, sublingual, or
transfugal? - Answer-Transfugal
How are intradermal drugs delivered? - Answer-By injection under the skin.
An injection of anesthetic directly into the bloodstream is an example of intravenous
drug delivery. - Answer-True
