NAPLEX antibiotics 2025 REAL EXAM QUESTIONS | 212 MOST TESTED QUESTIONS AND CORRECT ANSWERS |100%
ACCURATE|GET IT RIGHT!!
MIC - correct answer lowest drug concentration that prevents visibile microbial growth in 24
hours
gram (+) bacteria species - correct answer staph, strep, EC, clostridium, listeria
which antibiotics exhibit time-dependent killing? - correct answer penicillins, cephalosporins
how can you increase the killing of a time-dependent antibiotic? - correct answer dose more
frequently, extend the infusion time
example of concentration-dependent antibiotic? - correct answer aminoglycosides (gentamicin,
tobramycin, amikacin)
what are the bacteriostatic antibiotics (protein synthesis inhibitors)? - correct answer
macrolides
aminoglycosides
tetracyclines
clindamycin
linezolid
quinupristin, dalfopristin
what is the MOA of penicillins, cephalosporins, carbapenems, and vancomycin? - correct
answer cell wall inhibitors - bactericidal
what general ADRs are the black box warning for aminoglycosides? - correct answer
nephrotoxicity and neurotoxicity
what are the aminoglycosides? - correct answer tobramycin
gentamicin
amikacin
what type of nephrotoxicity do aminoglycosides cause? - correct answer ATN - acute tubular
necrosis
what weight do you use to dose aminoglycosides? - correct answer IBW (unless TBW is less)
*use ABW if obese ( > 30% IBW)
what organisms are aminoglycosides mainly active against? - correct answer gram (-): GNR, PA
extended interval dosing of the aminoglycosides? - correct answer gent/tobra: 4-7 mg/kg
amikacin: 15-20 mg/kg
,NAPLEX antibiotics 2025 REAL EXAM QUESTIONS | 212 MOST TESTED QUESTIONS AND CORRECT ANSWERS |100%
ACCURATE|GET IT RIGHT!!
*draw random level within 6-16 hours after dose
adjust body weight (ABW) formula? - correct answer IBW + [0.4(TBW - IBW)]
desired trough (traditional dosing) for gent/tobra? peak? - correct answer trough: < 2 mcg/mL
peak: 5-10 mcg/mL
amoxicilin brand name - correct answer Amoxil
what organisms do the penicillins cover? - correct answer mainly gram (+), some gram (-)
which penicillin is the DOC in acute otitis media? - correct answer amoxicillin
which penicillin has activity against PA? - correct answer piperacillin
which penicillins do not require renal dosing? - correct answer nafcillin
oxacillin
dicloxacillin
Does Amoxil suspension need to be refrigerated? - correct answer no - stable for 14 days at
room temperature
how do you need to take Pen VK? - correct answer on an empty stomach
what IV fluid is ampicillin only compatible with? - correct answer NS
what are the main penicillin drug interactions? - correct answer probenacid, allopurinol -
increased penicillin levels
may decrease levels of oral contraceptives
what type of killing do cephalosporins exhibit? - correct answer time-dependent
what are the first generation cephalosporins? - correct answer cefazolin and cephalexin
what organisms are every cephalosporin active against? - correct answer strep/staph and GNR
which cephalosporins are active against PA? - correct answer cefepime and ceftazidime
cefazolin brand name? - correct answer Kefzol
cephalexin brand name? - correct answer Keflex
ceftriaxone brand name and generation? - correct answer Rocephin - 3rd gen
cefuroxime brand name? - correct answer Ceftin, Zinacef
what is the lone 4th generation cephalosporin? - correct answer cefepime (Maxipime) - 1-2 g
Q8-12
, NAPLEX antibiotics 2025 REAL EXAM QUESTIONS | 212 MOST TESTED QUESTIONS AND CORRECT ANSWERS |100%
ACCURATE|GET IT RIGHT!!
what generation is ceftaroline (Teflaro) in? - correct answer 5th
what are the main side effects of cephalosporins? - correct answer seizures with accumulation
increased LFTs
GI upset, diarrhea
bone marrow suppression
which cephalosporins DO NOT require renal dose adjustments? - correct answer ceftriaxone
(Rocephin) - 3rd generation
what are the main drug interactions of cephalosporins? - correct answer probenacid,
allopurinol - increased levels of cephalosporins
may decrease effectiveness of oral contraceptives
What type of killing do carbapenems exhibit? - correct answer time-dependent bactericidal
generic name for Primaxin? - correct answer imipenem / cilastatin
what organisms do the carbapenems cover? - correct answer everything
*ertapenem = no EC or PA
*no MRSA
Brand name for meropenem? - correct answer Merrem
Brand name for ertapenem? - correct answer Invanz
Brand name for Doripenem? - correct answer Doribax
can carbapenems be used in a PCN allergy? - correct answer NO
carbapenem drug interactions? - correct answer uricosuric agents (probenacid, allopurinol)
caution with seizures
MOA of flouroquinolones - correct answer inhibit bacterial DNA topoisomerase IV and inhibit
DNA gyrase
what type of killing to flouroquinolones exhibit? - correct answer concentration-dependent
bactericidal
brand name of moxifloxacin? - correct answer Avelox
what do flouroquinolones have a black box warning for? - correct answer tendon inflammation
and rupture
ACCURATE|GET IT RIGHT!!
MIC - correct answer lowest drug concentration that prevents visibile microbial growth in 24
hours
gram (+) bacteria species - correct answer staph, strep, EC, clostridium, listeria
which antibiotics exhibit time-dependent killing? - correct answer penicillins, cephalosporins
how can you increase the killing of a time-dependent antibiotic? - correct answer dose more
frequently, extend the infusion time
example of concentration-dependent antibiotic? - correct answer aminoglycosides (gentamicin,
tobramycin, amikacin)
what are the bacteriostatic antibiotics (protein synthesis inhibitors)? - correct answer
macrolides
aminoglycosides
tetracyclines
clindamycin
linezolid
quinupristin, dalfopristin
what is the MOA of penicillins, cephalosporins, carbapenems, and vancomycin? - correct
answer cell wall inhibitors - bactericidal
what general ADRs are the black box warning for aminoglycosides? - correct answer
nephrotoxicity and neurotoxicity
what are the aminoglycosides? - correct answer tobramycin
gentamicin
amikacin
what type of nephrotoxicity do aminoglycosides cause? - correct answer ATN - acute tubular
necrosis
what weight do you use to dose aminoglycosides? - correct answer IBW (unless TBW is less)
*use ABW if obese ( > 30% IBW)
what organisms are aminoglycosides mainly active against? - correct answer gram (-): GNR, PA
extended interval dosing of the aminoglycosides? - correct answer gent/tobra: 4-7 mg/kg
amikacin: 15-20 mg/kg
,NAPLEX antibiotics 2025 REAL EXAM QUESTIONS | 212 MOST TESTED QUESTIONS AND CORRECT ANSWERS |100%
ACCURATE|GET IT RIGHT!!
*draw random level within 6-16 hours after dose
adjust body weight (ABW) formula? - correct answer IBW + [0.4(TBW - IBW)]
desired trough (traditional dosing) for gent/tobra? peak? - correct answer trough: < 2 mcg/mL
peak: 5-10 mcg/mL
amoxicilin brand name - correct answer Amoxil
what organisms do the penicillins cover? - correct answer mainly gram (+), some gram (-)
which penicillin is the DOC in acute otitis media? - correct answer amoxicillin
which penicillin has activity against PA? - correct answer piperacillin
which penicillins do not require renal dosing? - correct answer nafcillin
oxacillin
dicloxacillin
Does Amoxil suspension need to be refrigerated? - correct answer no - stable for 14 days at
room temperature
how do you need to take Pen VK? - correct answer on an empty stomach
what IV fluid is ampicillin only compatible with? - correct answer NS
what are the main penicillin drug interactions? - correct answer probenacid, allopurinol -
increased penicillin levels
may decrease levels of oral contraceptives
what type of killing do cephalosporins exhibit? - correct answer time-dependent
what are the first generation cephalosporins? - correct answer cefazolin and cephalexin
what organisms are every cephalosporin active against? - correct answer strep/staph and GNR
which cephalosporins are active against PA? - correct answer cefepime and ceftazidime
cefazolin brand name? - correct answer Kefzol
cephalexin brand name? - correct answer Keflex
ceftriaxone brand name and generation? - correct answer Rocephin - 3rd gen
cefuroxime brand name? - correct answer Ceftin, Zinacef
what is the lone 4th generation cephalosporin? - correct answer cefepime (Maxipime) - 1-2 g
Q8-12
, NAPLEX antibiotics 2025 REAL EXAM QUESTIONS | 212 MOST TESTED QUESTIONS AND CORRECT ANSWERS |100%
ACCURATE|GET IT RIGHT!!
what generation is ceftaroline (Teflaro) in? - correct answer 5th
what are the main side effects of cephalosporins? - correct answer seizures with accumulation
increased LFTs
GI upset, diarrhea
bone marrow suppression
which cephalosporins DO NOT require renal dose adjustments? - correct answer ceftriaxone
(Rocephin) - 3rd generation
what are the main drug interactions of cephalosporins? - correct answer probenacid,
allopurinol - increased levels of cephalosporins
may decrease effectiveness of oral contraceptives
What type of killing do carbapenems exhibit? - correct answer time-dependent bactericidal
generic name for Primaxin? - correct answer imipenem / cilastatin
what organisms do the carbapenems cover? - correct answer everything
*ertapenem = no EC or PA
*no MRSA
Brand name for meropenem? - correct answer Merrem
Brand name for ertapenem? - correct answer Invanz
Brand name for Doripenem? - correct answer Doribax
can carbapenems be used in a PCN allergy? - correct answer NO
carbapenem drug interactions? - correct answer uricosuric agents (probenacid, allopurinol)
caution with seizures
MOA of flouroquinolones - correct answer inhibit bacterial DNA topoisomerase IV and inhibit
DNA gyrase
what type of killing to flouroquinolones exhibit? - correct answer concentration-dependent
bactericidal
brand name of moxifloxacin? - correct answer Avelox
what do flouroquinolones have a black box warning for? - correct answer tendon inflammation
and rupture
