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CHEMOTHERAPY/IMMUNOTHERAPY CERTIFICATE COURSE (ONS,ONCC)CORRECT 100%

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Alkylating agents - ANSWER Classification Break DNA helix strand, thereby interfering with DNA replication Altretamine (Hexalen) - ANSWER Alkylating Agent PO Ovarian CA Side effects- nausea, vomiting, skin rash, hypersensitivity reaction, diarrhea Dose limiting - neuro-toxicity, peripheral neuropathy, myelosuppression Bendamustine (Treanda/Bendeka) - ANSWER Alkylating agent IV CLL or Indolent NHL Side effects- pyrexia, nausea, vomiting, skin reactions, TLS, hepatotoxicity, vein irritation

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ONS/ONCC Chemotherapy Immunotherapy Certification
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Written for

Institution
ONS/ONCC Chemotherapy Immunotherapy Certification
Course
ONS/ONCC Chemotherapy Immunotherapy Certification

Document information

Uploaded on
March 21, 2025
Number of pages
2
Written in
2024/2025
Type
Exam (elaborations)
Contains
Questions & answers

Subjects

  • chemotherapyimmunotherapy
  • chemotherapyimmunotherapy certificate course ons
  • alkylating agents answer classification break dn
  • altretamine hexalen answer alkylating agent po

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CHEMOTHERAPY/IMMUNOTHERAPY
CERTIFICATE COURSE
(ONS,ONCC)CORRECT 100%
Alkylating agents - ANSWER Classification
Break DNA helix strand, thereby interfering with DNA replication

Altretamine (Hexalen) - ANSWER Alkylating Agent
PO
Ovarian CA
Side effects- nausea, vomiting, skin rash, hypersensitivity reaction, diarrhea
Dose limiting - neuro-toxicity, peripheral neuropathy, myelosuppression

Bendamustine (Treanda/Bendeka) - ANSWER Alkylating agent
IV
CLL or Indolent NHL
Side effects- pyrexia, nausea, vomiting, skin reactions, TLS, hepatotoxicity, vein
irritation
Dose limiting - myelosuppression

Irritant and vesicant properties

infusion reactions likely to occur in 2nd or subsequent infusions

Busulfan (IV busulfex: PO Myleran) - ANSWER Alkylating Agent
IV or PO
CML and Stem cell prep
Side effects - profound tachycardia, HTN, chest pain, hyperpigmentation, alopecia,
infertility, confusion, suizures, mucositis, nausea, vomiting, insomnia, hyperglycemia,
blurred vision, secondary malignancy, VOD (now sinusoidal obstruction syndrome)

seizure prophylaxis
central line only for IV

Cisplatin - ANSWER Alkylating agent
IV
Ovarian, Testicular, Bladder
Side Effects - severe acute and delayed CINV, ototoxicity, hyperuricemia,
hypersensitivity, electrolyte abnormalities, peripheral neuropathy
Dose Limiting - nephrotoxicity, myelosupression
Carboplatin - ANSWER Alkylating agent
IV
Ovarian CA
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