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Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
mi mi mi mi mi mi mi mi mi mi
Multiple Choice
mi
Identify the choice that best completes the statement or answers the question.
mi mi mi mi mi mi mi mi mi mi mi
1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?
mi mi mi mi mi mi mi mi mi mi mi mi mi
a. Pentose phosphate shunt c. Glycolysis
mi mi
b. Luebering-Rapoport shunt d. Methemoglobin reductase mi m i mi
2. A unit of blood was returned to the blood bank before it was spiked. Apparently the patient’s IV failed.
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
The unit of blood was outside the blood bank for 35 minutes. Which of the statements below is most
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
accurate? mi
a. The unit of blood should be discarded immediately.
mi mi mi mi mi mi mi
b. The unit of blood can be returned to inventory.
mi mi mi mi mi mi mi mi
c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time.
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
d. The unit of blood must be transfused with 24 hours.
mi mi mi mi mi mi mi mi mi
3. What is the average diameter of a platelet?
mi mi mi mi mi mi mi
a. 5 to 10 µm mi mi mi c. 1 to 2 µm mi mi mi
b. 2 to 4 µm mi mi mi d. 4 to 6 µm
m i m i mi mi mi
4. In the normal hemoglobin-
mi mi mi
oxygen dissociation curve, what percentage of oxygen is released to the tissues when PO2 averages
mi mi mi mi mi mi mi mi mi mi mi mi mi m i m
40 mm Hg? i mi mi
a. 75% c. 100%
b. 25% d. 50% m i
5. What factors are known to influence platelet metabolism and function?
mi mi mi mi mi mi mi mi mi
a. Storage temperature c. Platelet count
mi mi
b. Initial pH d. All of the above
mi m i mi mi mi
6. Which of the following red blood cell morphologies may be present on the peripheral blood smear as a
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
result of loss of RBC membrane?
mi mi mi mi mi
a. Spherocytes c. Burr cells mi
b. Target cells d. Schistocytes
mi m i
7. What does the term autologous transfusion refer to?
mi mi mi mi mi mi mi
a. A parent donating blood for his or her child
mi mi mi mi mi mi mi mi
b. An individual donating blood for a friend
mi mi mi mi mi mi
c. An individual donating blood for a relative
mi mi mi mi mi mi
d. An individual donating blood for his or her own transfusion
mi mi mi mi mi mi mi mi mi
8. What is the primary function of hemoglobin?
mi mi mi mi mi mi
a. Iron metabolism mi c. Oxygen transport mi
b. Porphyrin synthesis d. Signal transduction mi m i mi
9. All of the following areas of red blood cell biology are crucial for normal erythrocyte survival except:
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
a. Cellular metabolism. c. Site of the ABO antigen attachment.
mi mi mi mi mi mi
b. RBC membrane. mid. Hemoglobin structure. m i mi
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m i 10. What is the correct biochemical composition of the RBC membrane?
m i mi mi mi mi mi mi mi mi mi
a. 52% protein, 40% lipid, 8% carbohydrate
mi mi mi mi mi
b. 40% protein, 8% lipid, 52% carbohydrate
mi mi mi mi mi
c. 8% protein, 52% lipid, 40% carbohydrate
mi mi mi mi mi
d. 8% lipid, 40% carbohydrate, 52% protein
mi mi mi mi mi
m i 11. All of the following biochemical changes are associated with loss of red blood cell viability upon storage
m i mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
except:
a. Decreased pH. c. Increased ATP level.
mi mi mi
b. Loss of red blood cell function. mi d. Decreased glucose consumption.
mi mi mi mi m i mi mi
m i 12.m i Which red blood cell preservative has a storage time of 35 days?
mi mi mi mi mi mi mi mi mi mi mi
a. ACD c. AS-1
b. CPDA-1 d. CPD m i m i
m i 13. The RBC membrane is relatively permeable to all of the following except:
m i mi mi mi mi mi mi mi mi mi mi mi
a. Chloride. c. Bicarbonate.
b. Sodium. d. Water. m i
mi 14. What percentage of platelets is sequestered in the spleen as functional reserve after being released fro
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
m the bone marrow?
mi mi mi
a. 30% c. 10%
b. 50% d. 25% m i m i
m i 15. What is the major biochemical consideration in platelet storage?
m i mi mi mi mi mi mi mi mi
a. Glucose metabolism c. Production of carbon dioxide
mi mi mi mi
b. Oxygen supply d. Regulation of pH
mi m i mi mi
mi 16. What would the hemoglobin-
mi mi mi mi
oxygen dissociation curve depict in a patient exhibiting clinical signs of alkalosis?
mi mi mi mi mi mi mi mi mi mi mi
a. Normal c. Shift to the right mi mi mi
b. Shift to the left mi d. None of the above
mi mi m i mi mi mi
m i 17. m iName the main lipid components of a red blood cell membrane.
mi mi mi mi mi mi mi mi mi mi
a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin A m i mi
m i 18. m iThe ABO blood groups were discovered in 1901 by whom?
mi mi mi mi mi mi mi mi mi
a. Charles Drew c. Loutit and Mollison
mi mi mi
b. Karl Landsteiner mi d. Edward Lindeman m i mi
m i 19. A standing order of platelets was shipped to your facility by your supplier. It was inadvertently left in
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
the corner of the department until discovered 36 hours later. What would the appropriate action be for
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
the blood banker?mi mi
a. If the temperature in the box was 22 +/-
mi mi mi mi mi mi mi mi
2°C and the platelet swirl seemed OK, it would be OK to accept the unit into invent
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
ory.
b. The platelets have fallen outside the supplier’s quality assurance. The unit should b
mi mi mi mi mi mi mi mi mi mi mi mi
e discarded because the pH has probably dropped too low and platelet activation has
mi mi mi mi mi mi mi mi mi mi mi mi mi
been compromised.
mi mi
c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
Thismistudymisourcemiwasmidownloadedmibymi100000826342158mifrommiCourseHero.commionmi09-15-
2021 17:54:15 GMT -05:00
https://www.coursehero.com/file/25537437/ch01rtf/
,
,https://www.stuvia.com/
Chapter 1 RBCs and Platelet Preservation: Historical Perspectives and Current Trends
mi mi mi mi mi mi mi mi mi mi
Multiple Choice
mi
Identify the choice that best completes the statement or answers the question.
mi mi mi mi mi mi mi mi mi mi mi
1. Which metabolic pathway is responsible for generating 90% of the ATP for the RBC?
mi mi mi mi mi mi mi mi mi mi mi mi mi
a. Pentose phosphate shunt c. Glycolysis
mi mi
b. Luebering-Rapoport shunt d. Methemoglobin reductase mi m i mi
2. A unit of blood was returned to the blood bank before it was spiked. Apparently the patient’s IV failed.
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
The unit of blood was outside the blood bank for 35 minutes. Which of the statements below is most
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
accurate? mi
a. The unit of blood should be discarded immediately.
mi mi mi mi mi mi mi
b. The unit of blood can be returned to inventory.
mi mi mi mi mi mi mi mi
c. The unit of blood must be transfused within 4 hours or be discarded at the end of that time.
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
d. The unit of blood must be transfused with 24 hours.
mi mi mi mi mi mi mi mi mi
3. What is the average diameter of a platelet?
mi mi mi mi mi mi mi
a. 5 to 10 µm mi mi mi c. 1 to 2 µm mi mi mi
b. 2 to 4 µm mi mi mi d. 4 to 6 µm
m i m i mi mi mi
4. In the normal hemoglobin-
mi mi mi
oxygen dissociation curve, what percentage of oxygen is released to the tissues when PO2 averages
mi mi mi mi mi mi mi mi mi mi mi mi mi m i m
40 mm Hg? i mi mi
a. 75% c. 100%
b. 25% d. 50% m i
5. What factors are known to influence platelet metabolism and function?
mi mi mi mi mi mi mi mi mi
a. Storage temperature c. Platelet count
mi mi
b. Initial pH d. All of the above
mi m i mi mi mi
6. Which of the following red blood cell morphologies may be present on the peripheral blood smear as a
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
result of loss of RBC membrane?
mi mi mi mi mi
a. Spherocytes c. Burr cells mi
b. Target cells d. Schistocytes
mi m i
7. What does the term autologous transfusion refer to?
mi mi mi mi mi mi mi
a. A parent donating blood for his or her child
mi mi mi mi mi mi mi mi
b. An individual donating blood for a friend
mi mi mi mi mi mi
c. An individual donating blood for a relative
mi mi mi mi mi mi
d. An individual donating blood for his or her own transfusion
mi mi mi mi mi mi mi mi mi
8. What is the primary function of hemoglobin?
mi mi mi mi mi mi
a. Iron metabolism mi c. Oxygen transport mi
b. Porphyrin synthesis d. Signal transduction mi m i mi
9. All of the following areas of red blood cell biology are crucial for normal erythrocyte survival except:
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
a. Cellular metabolism. c. Site of the ABO antigen attachment.
mi mi mi mi mi mi
b. RBC membrane. mid. Hemoglobin structure. m i mi
Thismistudymisourcemiwasmidownloadedmibymi100000826342158mifrommiCourseHero.commionmi09-15-
2021 17:54:15 GMT -05:00
https://www.coursehero.com/file/25537437/ch01rtf/
,https://www.stuvia.com/
m i 10. What is the correct biochemical composition of the RBC membrane?
m i mi mi mi mi mi mi mi mi mi
a. 52% protein, 40% lipid, 8% carbohydrate
mi mi mi mi mi
b. 40% protein, 8% lipid, 52% carbohydrate
mi mi mi mi mi
c. 8% protein, 52% lipid, 40% carbohydrate
mi mi mi mi mi
d. 8% lipid, 40% carbohydrate, 52% protein
mi mi mi mi mi
m i 11. All of the following biochemical changes are associated with loss of red blood cell viability upon storage
m i mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
except:
a. Decreased pH. c. Increased ATP level.
mi mi mi
b. Loss of red blood cell function. mi d. Decreased glucose consumption.
mi mi mi mi m i mi mi
m i 12.m i Which red blood cell preservative has a storage time of 35 days?
mi mi mi mi mi mi mi mi mi mi mi
a. ACD c. AS-1
b. CPDA-1 d. CPD m i m i
m i 13. The RBC membrane is relatively permeable to all of the following except:
m i mi mi mi mi mi mi mi mi mi mi mi
a. Chloride. c. Bicarbonate.
b. Sodium. d. Water. m i
mi 14. What percentage of platelets is sequestered in the spleen as functional reserve after being released fro
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
m the bone marrow?
mi mi mi
a. 30% c. 10%
b. 50% d. 25% m i m i
m i 15. What is the major biochemical consideration in platelet storage?
m i mi mi mi mi mi mi mi mi
a. Glucose metabolism c. Production of carbon dioxide
mi mi mi mi
b. Oxygen supply d. Regulation of pH
mi m i mi mi
mi 16. What would the hemoglobin-
mi mi mi mi
oxygen dissociation curve depict in a patient exhibiting clinical signs of alkalosis?
mi mi mi mi mi mi mi mi mi mi mi
a. Normal c. Shift to the right mi mi mi
b. Shift to the left mi d. None of the above
mi mi m i mi mi mi
m i 17. m iName the main lipid components of a red blood cell membrane.
mi mi mi mi mi mi mi mi mi mi
a. Phospholipid c. Glycolipid
b. Sphingomyelin d. Glycophorin A m i mi
m i 18. m iThe ABO blood groups were discovered in 1901 by whom?
mi mi mi mi mi mi mi mi mi
a. Charles Drew c. Loutit and Mollison
mi mi mi
b. Karl Landsteiner mi d. Edward Lindeman m i mi
m i 19. A standing order of platelets was shipped to your facility by your supplier. It was inadvertently left in
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
the corner of the department until discovered 36 hours later. What would the appropriate action be for
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
the blood banker?mi mi
a. If the temperature in the box was 22 +/-
mi mi mi mi mi mi mi mi
2°C and the platelet swirl seemed OK, it would be OK to accept the unit into invent
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
ory.
b. The platelets have fallen outside the supplier’s quality assurance. The unit should b
mi mi mi mi mi mi mi mi mi mi mi mi
e discarded because the pH has probably dropped too low and platelet activation has
mi mi mi mi mi mi mi mi mi mi mi mi mi
been compromised.
mi mi
c. If the temperature was 1°C to 6°C and the platelet swirl seemed OK, it would be OK to
mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi mi
Thismistudymisourcemiwasmidownloadedmibymi100000826342158mifrommiCourseHero.commionmi09-15-
2021 17:54:15 GMT -05:00
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