6665 by (Lee et al., 2023)
Signs and symptoms according to the DSM-5-TR Deficits in intellectual functioning and
adaptive functioning (Lee et al., 2023)
Occurring before the age of 22 (Lee et al., 2023)
Differential diagnoses Child abuse, debilitating medical diseases, cerebral palsy, sensory
disability, and speech disorder (Lee et al., 2023)
Incidence Peaks between 10 and 14 years old (Lee et al., 2023)
1.5x more prevalent in males versus females (Lee et al., 2023)
Etiology Genetic- Phenylketonuria, Lesch-Nyhan syndrome, Fragile X syndrome, and Rett
syndrome are all inborn errors of metabolism that can cause neurodevelopmental defects or
neurodegeneration (Lee et al., 2023)
Environmental- Toxic substances (alcohol, illicit drugs), infectious agents (rubella, HIV), and
uncontrolled maternal medical conditions (hypertension, asthma, urinary tract infection, pre-
pregnancy obesity, or pre-pregnancy diabetes) (Lee et al., 2023)
Prognosis Deficits seen in intellectual disability are permanent (Lee et al., 2023)
With adequate interventions those with; Mild intellectual disability might achieve adequate
language and social skills to function independently (Lee et al., 2023) Moderate intellectual
disability might achieve a second-grade level of language and social skills (Lee et al., 2023)
Severe intellectual disability might not be able to communicate orally (Lee et al., 2023)
Considerations related to culture, gender, age Age, development, and language need to be
taken into consideration when educating those about intellectual disability