MDC 2 Exam 1
1. What are the 1. Initiation
stages of cell 2. Promotion
growth in cancer 3. Progression
development? 4. Metastasis
2. What happens normal cells become damaged and leads to development of cancer (Malignant
during Initia- Transformation)
tion phase dur- this is irreversible
ing cancer cell
growth?
3. What happens -repeat exposure to carcinogen enhances cell growth which leads to mutation
during the pro- -enhanced cell growth of cells by promotors (like hormones primarily estrogen)
motion stage -period between initiation and growth into a tumor is called a latency period
during cancer cell
growth?
4. What happens -An increase in the production of malignant cells
during the pro- -after a tumor reach 1 cm, it already has 1 billion cells
gression stage -when it builds its own blood supply it becomes a health problem
of cancer cell
growth?
5. What happens -movement of cells from the primary site and establishing remote colonies
during the
Metastasis stage
of cancer cell
growth?
, MDC 2 Exam 1
6. Malignant vs. Be- Malignant
nign -Anaplasia-loss of appearance of parent cell
-A larger nuclear-to-cytoplasmic ration
-Specific functions are lost-serve NO purpose
-Loose adherence-loosely bound due to the lack fo fibronectin production
-migration-spreads easily (metastasis)
-Contact inhibition does not occurs
-Rapid or continuous cell division
-Aneuploidy: Abnormal Chromosomes
Benign (SASTNOE)
-specific morphology
-a smaller nuclear-to-cytoplasm ration
-specific differentiated function
-Tight adherence, bind closely together due to production of fibronectin
-No migration
-Orderly growth
-Euploidy: Normal chromosomes per cell
7. Which cancers Leukemias
arise from blood?
8. Which cancers af- Lymphomas
fect the lymph?
9. Which cancers Carcinomas
originate in the
epithelial cells
1. What are the 1. Initiation
stages of cell 2. Promotion
growth in cancer 3. Progression
development? 4. Metastasis
2. What happens normal cells become damaged and leads to development of cancer (Malignant
during Initia- Transformation)
tion phase dur- this is irreversible
ing cancer cell
growth?
3. What happens -repeat exposure to carcinogen enhances cell growth which leads to mutation
during the pro- -enhanced cell growth of cells by promotors (like hormones primarily estrogen)
motion stage -period between initiation and growth into a tumor is called a latency period
during cancer cell
growth?
4. What happens -An increase in the production of malignant cells
during the pro- -after a tumor reach 1 cm, it already has 1 billion cells
gression stage -when it builds its own blood supply it becomes a health problem
of cancer cell
growth?
5. What happens -movement of cells from the primary site and establishing remote colonies
during the
Metastasis stage
of cancer cell
growth?
, MDC 2 Exam 1
6. Malignant vs. Be- Malignant
nign -Anaplasia-loss of appearance of parent cell
-A larger nuclear-to-cytoplasmic ration
-Specific functions are lost-serve NO purpose
-Loose adherence-loosely bound due to the lack fo fibronectin production
-migration-spreads easily (metastasis)
-Contact inhibition does not occurs
-Rapid or continuous cell division
-Aneuploidy: Abnormal Chromosomes
Benign (SASTNOE)
-specific morphology
-a smaller nuclear-to-cytoplasm ration
-specific differentiated function
-Tight adherence, bind closely together due to production of fibronectin
-No migration
-Orderly growth
-Euploidy: Normal chromosomes per cell
7. Which cancers Leukemias
arise from blood?
8. Which cancers af- Lymphomas
fect the lymph?
9. Which cancers Carcinomas
originate in the
epithelial cells
