BCHM 4360 Exam 1 Chapter 6
Terms in this set (395)
Before cells divide, DNA replication
___________________must
occur
DNA replication is the copying
complete, faithful
_____of the DNA comprising
the cell's
chromosomes
What type of semi-conservative
replication is DNA
replication?
each strand of the parental double helix acts as
Semi-conservative
replication a template for the synthesis of a new daughter
DNA strand
in order to copy the base; complementary base
template strand:
1._______the on the
template strand must be
identified
2. the______must be added
In DNA, A pairs with T; C
________________and G
pairs with
_________
nucleotides are added to 3'
the_________________end
copying the template identical; identical
strand ensures that
each daughter double-
helix is________________to
the
parental double-
helix and that each
daughter cell will
receive
____________________
DNA
molecules
replication starts at special origins of replication
sites called
replication moves away replication bubble
,from the origin in both
directions, forming a
,the DNA double-helix is origin of replication; replication forks
opened at the
_____________and unwound
to form
_____________________
at replication forks, is ssDNA; DNA synthesis
exposed and
_______can occur
DNA synthesis on both 5'; 3'
strands occurs in a
____ to__direction
DNA synthesis is leading; lagging
continuous on one
strand, the strand, but
discontinuous on the
other strand, the strand
DNA synthesis is on the continuous
leading
strand
DNA synthesis is on the discontinuous
lagging
strand
the leading strand one; multiple
requires___________primer,
while the lagging strand
requires ______
1. Initiation
three phases of DNA 2. Elongation
synthesis 3.Termination
the origin of replication initiator protein
is recognized by an
initiator proteins open up double helix; helicases
the _________ _____ and
recruit ________
DNA helicases the helix unwind; ssDNA
to expose
__________
single-stranded DNA is ssDNA binding proteins
coated with
initiation is controlled to once
occur________________per
cell
cycle
DNA synthesis needs a primer
, _________________that can
only
add nucleotides to an
existing 3' end
DNA synthesis primer is primase
a short RNA strand
synthesized by
after the RNA primer is sliding clamp
synthesized, the
_________is recruited
DNA polymerase is clamp loader; sliding clamp
associated with DNA via
the _______ _________ and the
________ ______
_______is associated with DNA polymerase
DNA via the
clamp loader and the
sliding clamp
the replication copying
machinery moves along
the DNA, the strands
each base in the parental DNA polymerase
DNA is read by
________adds DNA polymerase
complementary bases to
the growing strand in a 5'
to 3' direction
DNA polymerase adds 5'; 3'
complementary bases to
the growing strand in a
____ to ____ direction
Terms in this set (395)
Before cells divide, DNA replication
___________________must
occur
DNA replication is the copying
complete, faithful
_____of the DNA comprising
the cell's
chromosomes
What type of semi-conservative
replication is DNA
replication?
each strand of the parental double helix acts as
Semi-conservative
replication a template for the synthesis of a new daughter
DNA strand
in order to copy the base; complementary base
template strand:
1._______the on the
template strand must be
identified
2. the______must be added
In DNA, A pairs with T; C
________________and G
pairs with
_________
nucleotides are added to 3'
the_________________end
copying the template identical; identical
strand ensures that
each daughter double-
helix is________________to
the
parental double-
helix and that each
daughter cell will
receive
____________________
DNA
molecules
replication starts at special origins of replication
sites called
replication moves away replication bubble
,from the origin in both
directions, forming a
,the DNA double-helix is origin of replication; replication forks
opened at the
_____________and unwound
to form
_____________________
at replication forks, is ssDNA; DNA synthesis
exposed and
_______can occur
DNA synthesis on both 5'; 3'
strands occurs in a
____ to__direction
DNA synthesis is leading; lagging
continuous on one
strand, the strand, but
discontinuous on the
other strand, the strand
DNA synthesis is on the continuous
leading
strand
DNA synthesis is on the discontinuous
lagging
strand
the leading strand one; multiple
requires___________primer,
while the lagging strand
requires ______
1. Initiation
three phases of DNA 2. Elongation
synthesis 3.Termination
the origin of replication initiator protein
is recognized by an
initiator proteins open up double helix; helicases
the _________ _____ and
recruit ________
DNA helicases the helix unwind; ssDNA
to expose
__________
single-stranded DNA is ssDNA binding proteins
coated with
initiation is controlled to once
occur________________per
cell
cycle
DNA synthesis needs a primer
, _________________that can
only
add nucleotides to an
existing 3' end
DNA synthesis primer is primase
a short RNA strand
synthesized by
after the RNA primer is sliding clamp
synthesized, the
_________is recruited
DNA polymerase is clamp loader; sliding clamp
associated with DNA via
the _______ _________ and the
________ ______
_______is associated with DNA polymerase
DNA via the
clamp loader and the
sliding clamp
the replication copying
machinery moves along
the DNA, the strands
each base in the parental DNA polymerase
DNA is read by
________adds DNA polymerase
complementary bases to
the growing strand in a 5'
to 3' direction
DNA polymerase adds 5'; 3'
complementary bases to
the growing strand in a
____ to ____ direction
