BCHM 4360 Exam I Chapter 6 Guide: 100% Accurate Questions & Answers for Guaranteed Success

BCHM 4360 - Exam 1: Chapter 6

Terms in this set (102)


Initiator protein in bacteria
DnaA
Member of AAA+ ATPases
Initiator protein in

Origin replication complex eukaryotes Has 6
(ORC)

subunits


Member of AAA+ ATPases
Autonomously replication In yeast, ORC binds the DNA at a conserved DNA sequenced
sequence called the
Cdc6 and Cdt1 Helicase loading proteins in eukaryotes
MCM Helicase in eukaryotes
Promote binding of polymerase epsilon in eukaryotes

Sld2 and GINS
Polymerase epsilon interacts with these and somehow
stimulates helicase so that you get strand
separation
OriC Origin of replication in E. coli
DnaA boxes Where E. coli initiator protein, DnaA, binds in the origin
DnaB Helicase in bacteria
DnaB (helicase in bacteria) is

DnaC loaded onto DNA by In bacteria


Analogous to Cdc6 and Cdt1 in eukaryotes
Cdc45 MCM2-7 (helicase in eukaryotes) is activated by accessory
proteins such as
Helicase in eukaryotes
CMG
Contains MCM, GINS, and Cdc45
Lagging strand Bacterial helicase moves along this strand
Leading strand Eukaryotic helicase moves along this strand
SSB Single stranded binding proteins in bacteria
Replication protein A (RPA) Single stranded binding proteins in eukaryotes
RNA Primer in bacteria

, RNA+DNA Primer in eukaryotes
Primase Makes RNA primer of about 10 nucleotides in eukaryotes
DNA polymerase alpha Adds a short piece of DNA behind RNA primer in eukaryotes
subunit
PCNA Sliding clamp in eukaryotes
Beta protein Sliding clamp in bacteria
Clamp loader in bacteria
Clamp loader
AAA+ ATPase
Clamp loader in eukaryotes
Replication factor C (RFC)
AAA+ ATPase
Polymerase delta (δ) Lagging strand synthesis in eukaryotes