Clinical Calculations, 9th Edition Test Bank by Joyce LeFever Kee (ch7-17)

Test Bank For Clinical Calculations, 9th Edition by Joyce LeFever Kee (ch7-17)


Chapter 07: Methods of Calculation for Individualized Drug Dosing
Kee: Clinical Calculations: With Applications to General and Specialty Areas, 9th
Edition


OTHER

Body Surface Area by Square Root

1. Order: cyclophosphamide 500 mg/m2 in 500 mL of normal saline
solution (NSS) over 90 minutes
Patient height and weight: 5 ft 10 in, 142 lb
Drug available: cyclophosphamide 100 mg dilute with 5 mL of sterile
water; yields 20 mg/mL
a. What is the patient’s body surface area (BSA) (m2)?
b. What is the total dose?
c. How many milliliters should you prepare?

ANS:

a.
b. 500 mg/m2  1.78 m2 = 890 mg
c. FE: 890 mg/100 mg  5 mL = 44.5 mL

OR




2. Order: cisplatin 50 mg/m2 in 500 mL of NSS intravenously over 90 minutes
Patient height and weight: 5 ft 6 in, 160 lb
Drug available: cisplatin 100 mg/100 mL
a. What is the patient’s BSA (m2)?
b. What is the total dose?
c. How many milliliters should you prepare?

ANS:

a.
b. 50 mg  1.84 m2 = 92 mg
c. FE: 92 mg/100 mg  100 mL = 92 mL

OR




3. For the following questions, use the square root method and/or nomogram. Note discrepancies
between methods.

, Test Bank For Clinical Calculations, 9th Edition by Joyce LeFever Kee (ch7-17)




Give dacarbazine 250 mg/m2/day  5 days.
Patient height: 5 ft 10 in
Patient weight: 173 lb
What is the daily dose with
a. square root method?
b. nomogram?

ANS:

a.
250 mg/m2/day  1.97 m2 = 493 mg/day
b. Height 70 in, weight 173 lb, intersects 2.02 m2
250 mg/m2/day  2.02 m2 = 505  500 mg/day

4. For the following questions, use the square root method and/or nomogram. Note discrepancies
between methods.

, Test Bank For Clinical Calculations, 9th Edition by Joyce LeFever Kee (ch7-17)




Give 5-fluorouracil 450 mg/m2/wk.
Patient height: 5 ft 6 in
Patient weight: 210 lb
What is the weekly dose with
a. square root method?
b. nomogram?

ANS:

a.
450 mg/m2/wk  2.10 m2 = 945 mg/wk
b. Height 66 in, weight 210 lb, intersects 2.04 m2
450 mg/m2/wk  2.04 m2 = 918  920 mg/wk

5. For the following questions, use the square root method and/or nomogram. Note discrepancies
between methods.

, Test Bank For Clinical Calculations, 9th Edition by Joyce LeFever Kee (ch7-17)




Give leucovorin 200 mg/m2/wk.
Patient height: 5 ft 6 in
Patient weight: 210 lb
What is the weekly dose with
a. square root method?
b. nomogram?

ANS:

a.
200 mg/m2/wk  2.10 m2 = 420 mg/wk
b. Height 66 in, weight 210 lb, intersects 2.04 m2
200 mg/m2/wk  2.04 m2 = 408.00  400 mg/wk

6. For the following questions, use the square root method and/or nomogram. Note discrepancies
between methods.