Georgette Module 1 & 2 Exam Questions
And Answers 2025 Update.
Lithium level - Answer✔0.6-1.2
Lithium toxicity level - Answer✔greater than or equal to 1.5
what is the gold standard for treating manic episodes? - Answer✔Lithium
What drug has evidence of anti-suicidal effects for bipolar disorder? - Answer✔Lithium
baseline labs to collect in order to R/O medical diagnoses prior to giving Lithium - Answer✔TSH
(r/o bipolar)
Creatinine (0.6-1.2)
BUN (10-20)
Pregnancy test
ECG if greater than 50 (inverted T-waves)
All psychotropics should have what test prior to giving for child-bearing age? -
Answer✔pregnancy test
what is considered child-bearing age? - Answer✔12-51
SE of Lithium? (endocrine) - Answer✔HYPOthyroidism
SE of Lithium? (CNS) - Answer✔**course hand tremors w/ toxicity
SE of Lithium? (dermatological) - Answer✔Maculopapular rash
SE of Lithium? (GI) - Answer✔diarrhea, vomiting, cramp, anorexia
**imp. because these become severe w/ toxicity
SE of Lithium? (Renal) - Answer✔diabetes insipidus (polyuria r/t polydipsia)
SE of Lithium? (Cardiac) - Answer✔T-wave inversions
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SE of Lithium? (Hematologic) - Answer✔leukocytosis (increased WBC)
Hypertensive Crisis occurs when..... - Answer✔MAOIs are taken in conjunction w/ foods
containing TYRAMINE (dietary precursor of NE)
Hypertensive crisis is _____-__________ and cannot be reversed unless..... - Answer✔life-
threatening & cannot be reversed unless more MAO is produced by the body
Hypertensive crisis & death can occur when MAOIs are taken in conjunction with which types of
meds?? - Answer✔***Meperidine
***Stimulants/other sympathomimetics
Decongestants/TCA/SGA/St. Johns Wort/L-tryptophan
Symptoms of Hypertensive crisis include - Answer✔sudden explosive-like HA in OCCIPITAL
region
Fever**
Treatment of Hypertensive Crisis - Answer✔1. d/c offending agent (MAOI)
2. administer PHENTOLAMINE
3. Stabilize fever
medication to reverse hypertensive crisis w/ MAOI? - Answer✔Phentolamine****
List of common MAOIs (don't need to memorize, just know what it looks like) -
Answer✔Isocarboxazid (Marplan)
Phenelzine (Nardil)
Selegiline (Emsam)
Tranylcypromine (Parnate)
Teratogenic risks of common psych meds (Benzo, Carbamazepine, Lithium, Depakote) -
Answer✔Benzo: floppy baby & cleft palate
Carbamazepine: neural tube defect
Lithium: Epstein's anomaly & Congenital heart defects (esp. 1st trimester)
Depakote: Neural tube defects (spec. spina bifida)
Lamicatal main SE - Answer✔Steven Johnson's Syndrome*** (SE below, KNOW)
- Fever**
- Sore throat (may feel like burning**
- Facial/tongue swelling**
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- Skin sloughing***
- Prodromal HA, malaise, Arthralgia, painful mucous membranes may occur BEFORE rash
Valproic Acid/Divalproex Sodium aka Depakote main SE - Answer✔Hepatotoxicity**
Pancreatitis**
Carbamazepine (Tegretol) main SE - Answer✔Agranulocytosis***
Aplastic Anemia***
Steven-Johnson's*** (mainly Asians HLAB-1502 allele)
Aplastic Anemia s/s - Answer✔pallor, fatigue, HA, fever, nose bleeds, bleeding gums, skin rash,
SOB
Carbamazepine when to d/c - Answer✔WBC 2000-3000
ANC < 1000
Rash/Steven Johnson's
Or s/s of aplastic anemia or agranulocytosis
What to test prior to prescribing Cabamazepine?? - Answer✔HLA-B 1502 allele in Asians d/t
Steven's Johnson Syndrome
Clozapine main SE - Answer✔Risk for NEUTROPENIA --> monitor for s/s of infection***
Neutropenia is monitored only by... - Answer✔ANC
when to d/c Clozapine? - Answer✔ANC <1000
WBC 2000-3000
Check ____ before starting female of childbearing age (12-51yr) on psychotropic med -
Answer✔HCG
Folic acid does what & what is the recommended dosage? - Answer✔supports neural tube
development during FIRST month of pregnancy--> ALWAYS encourage those of childbearing age
to take (OTC medication)
Dosage= 0.4-0.8mg daily for all women planning or capable of becoming pregnant**
Symptoms of Steven's Johnson Syndrome - Answer✔Fever
Sore throat (burning feeling)
Facial/Tongue Swelling
Rash
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