PREP- MOCK TEST QUESTIONS
AND ANSWERS KEY.
What are the adverse effects of Statins? - Answer-Mild GI irritation
Rash
Headahce
Myopathy***
Why is it important to teach the patient to report muscle pain while taking Statins? -
Answer-Muscle pain can lead to rhabdomyolysis, which can strain the kidney causing
acute failure and even death
What is an example of Bile-Acid sequestrants? - Answer-Cholestyramine
What do bile acid sequestrants do? - Answer-They bind bile and prevents reabsorption
from the small intestines, which inhibits the absorption of cholesterol from the small
intestines.
The cholesterol is naturally secreted.
What are contraindications of Bile-Acid sequestrants? - Answer-Known allergy
Bowel obstruction*
Phenylketonuria (PKU)
What are the adverse effects of Bile-Acid sequestrants? - Answer-Constipation
Belching
Nausea
Bloating
Headache
Tinnitus
Burnt odor to urine
How does Niacin work? - Answer-Exact mechanism is unknown.
What are contraindications of Niacin? - Answer-Known allergy
HTN
Liver disease
Peptic ulcer
Bleeding
What are the adverse effects of Niacin? - Answer-GI discomfort
, Flushing*
Pruritus
How can you prevent flushing in Niacin? - Answer-Take aspirin 30 minutes before
administration
What is an example of a Fibric Acid Derivatives (Fibrates)? - Answer-Gemfibrozil
How do Fibrates work? - Answer-They breakdown cholesterol by activating the enzyme
lipoprotein lipase
They also change coagulation by decreasing platelet adhesiveness!
What are contraindications of Fibrates? - Answer-Warfarin use ( ^ pt)
Known allergy
Kidney disease
Liver disease
Cirrhosis
Gallbladder disease
What are adverse effects of Fibrates? - Answer-GI discomfort
Prolonged Prothrombin time
Elevated liver enzymes
What are nursing interventions for antilipemics? - Answer-Report muscle soreness,
changes in urine color, fever, malaise, nausea, or vomiting
Limit grapefruit juice
ALL medications must be taken one hour before or 4-6 hours after
Decreases absorption of vitamines ADEK
Increase action of oral anticoagulants
Increased risk of rhado when used in combo with statins
Can alter Hgb, Hct, WBC
Limit ETOH
Increase fiber and fluids
What are the components that affect heart failure? - Answer-Cardiac output: preload &
afterload
Contractility
Ejection fraction
What is the difference between cardiac output and ejection fraction? - Answer-Cardiac
output is the amount of blood that is stroked out per minute while the ejection fraction is
the amount of blood pumped out each contraction