ACTUAL Exam Questions and CORRECT
Answers
Parmacogenetics - CORRECT ANSWER - the study of genetic differences in drug
responses when referring to one gene
Pharmacogenomics - CORRECT ANSWER - the study of variances in drug response
when studying all genes
Phenotype - CORRECT ANSWER - physical appearance/function from the
genotype/environment
Genetic polymorphism - CORRECT ANSWER - differences in alleles usually a single
nucleotide variation that causes a person to respond differently to a drug.
drug polymorphism - CORRECT ANSWER - effect of a patient's age, gender, size, body
composition and other characteristics on the pharmacokinetics of specific drugs
What are the difference regarding FDA approval for prescription, OTC, herbal supplements -
CORRECT ANSWER - Prescription and OTC are FDA approved and Herbal supplements
are NOT FDA approve can cause side effects
Clinical trials 1 - CORRECT ANSWER - pharmacokinetics and metabolism
clinical trials 2 - CORRECT ANSWER - effectiveness and adverse effect
clinical trials 3 - CORRECT ANSWER - safety, effectiveness, and dosage range
, clinical trials 4 - CORRECT ANSWER - post marketing
When can drugs be prescribed to the general public - CORRECT ANSWER - after it pass
phase 3
What do control substance schedule mean? - CORRECT ANSWER - abuse and
dependency
Which pregnancy class is safe to use - CORRECT ANSWER - class A
which pregnancy class you should never use - CORRECT ANSWER - class X
How do genetic polymorphism impact drug therapy - CORRECT ANSWER - changes to
DNA outside the nucleus to determine the treatment outcome of a pharmacologic agent
Generic drug name - CORRECT ANSWER - safest, FDA approve, unique
trade name - CORRECT ANSWER - can be more than one, pharmaceutical name it
drug formulation - CORRECT ANSWER - liquid and solids
4 pharmacokinetic processes - CORRECT ANSWER - Absorption
Distribution
Metabolism
Elimination
bioavailabilty - CORRECT ANSWER - extent of absorption