Test Bank For Karch's Focus on Nursing Pharmacology, Ninth Edition Rebecca Tucker
Test Generator Questions, Chapter 1, Introduction to Drugs
Format: Multiple Choice
Chapter: 1
Client Needs: Physiological Integrity: Pharmacological and
Parenteral Therapies
Cognitive Level: Analyze
Difficulty: Moderate
Integrated Process: Nursing Process
Objective: 1
Page and Header: 3, Introduction
1. A nurse working in radiology administers iodine to a client
who is having a computed tomography (CT) scan. The nurse working on the
oncology unit administers chemotherapy to clients who have cancer. At the Public
Health Department, a nurse administers a measles–mumps–rubella (MMR)
vaccine to a 14-month-old child as a routine immunization. Which branch of
pharmacology best describes the actions of all three nurses?
A) pharmacoeconomics
B) pharmacotherapeutics
C) pharmacodynamics
D) pharmacokinetics
Ans: B
Feedback: Pharmacology is the study of the biologic effects of chemicals. Nurses
are involved with clinical pharmacology or pharmacotherapeutics, which is a
branch of pharmacology that deals with the uses of drugs to treat, prevent, and
diagnose disease. The radiology nurse is administering a drug to help diagnose a
disease. The oncology nurse is administering a drug to help treat a disease.
Pharmacoeconomics includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body, and pharmacokinetics
is how the body acts on the body.
Format: Multiple
, Test Bank For Karch's Focus on Nursing Pharmacology, Ninth Edition Rebecca Tucker
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Cognitive Level: Understand
Difficulty: Easy
Integrated Process: Nursing Process
Objective: 3
Page and Header: Legal Regulation of Drugs, 19, Box 1.2
2. The care provider has prescribed intravenous hydromorphone, an opioid, for a
client using a client-controlled analgesia (PCA) pump. The nurse is aware that
this drug has a high abuse potential. Under what category would hydromorphone
be classified?
A) schedule I
B) schedule II
C) schedule III
D) shedule IV
Ans: B
Feedback: Opioids with a high abuse potential are classified as schedule II
drugs because of severe dependence liability. Schedule I drugs have high abuse
potential and no accepted medical use. Schedule III drugs have a lesser abuse
potential than schedule II drugs and an accepted medical use. Schedule IV drugs
have low abuse potential and limited dependence liability.
Format: Multiple Choice
Chapter: 1
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Cognitive Level: Apply
Difficulty: Moderate
Integrated Process: Nursing Process
Objective: 2
Page and Header: 14, Drug Evaluation
3. When involved in phase III drug evaluation studies, what action should the
nurse perform?
A) Work with animals which are given experimental drugs.
, Test Bank For Karch's Focus on Nursing Pharmacology, Ninth Edition Rebecca Tucker
B) Select appropriate clients to be involved in the drug study.
C) Monitor and observe clients closely for adverse effects.
D) Make decisions that will determine effectiveness of the drug.
Ans: C
Feedback: Phase III studies involve use of a drug in a larger sample of the
population. The purpose is to determine the treatment benefit and to monitor
side effects that may not have been apparent in the earlier studies. Phase I
studies involve healthy human volunteers who are usually paid for their
participation. Nurses may observe for adverse effects and toxicity. Nurses may
be responsible for helping collect and analyze the information to be shared with
the Food and Drug Administration (FDA) but would not conduct research
independently because nurses do not prescribe medications. Use of animals in
drug testing is done in the preclinical trials. Select clients who are involved in
phase II studies have the disease the drug is intended to treat. These clients are
monitored closely for drug action and adverse effects.
Format: Multiple Choice
Chapter: 1
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Cognitive Level: Analyze
Difficulty: Moderate
Integrated Process: Nursing Process
Objective: 4
Page and Header: 22, Legal Regulation of Drugs
4. What concept is prioritized when a provider is considering the substitution of
brand name drug with a generic drug?
A) bioequivalency
B) critical concentration
C) distribution
D) half-life
Ans: A
, Test Bank For Karch's Focus on Nursing Pharmacology, Ninth Edition Rebecca Tucker
Feedback: The goal is that the generic medication is bioequivalent (has the
same effect on the body) to the brand name medication. Binders used in a
generic drug may not be the same as those used in the brand name drug.
Therefore, the way the body breaks down and uses the drug may differ, which
may eliminate a generic drug substitution. Critical concentration is the amount of
a drug that is needed to cause a therapeutic effect and should not differ between
generic and brand name medications. Distribution is the phase of
pharmacokinetics, which involves the movement of a drug to the body’s tissues
and is the same in generic and brand name drugs. A drug’s half-life is the time it
takes for the amount of drug to decrease to half the peak level, which should not
change when substituting a generic medication.
Format: Multiple Choice
Chapter: 1
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Cognitive Level: Apply
Difficulty: Moderate
Integrated Process: Nursing Process
Objective: 5
Page and Header: 23, Legal Regulation of Drugs
5. A nurse is assessing the client’s home medication use. After listening to the
client list current medications, the nurse asks what priority question?
A) “Do you take any generic medications?”
B) “Are any of these medications orphan drugs?”
C) “Are these medications safe to take during pregnancy?”
D) “Do you take any over-the-counter medications?”
Ans: D
Feedback: It is important for the nurse to specifically question use of over-the-
counter medications because clients may not consider them important. The client
is unlikely to know the meaning of “orphan drugs” unless they are a healthcare
provider. Safety during pregnancy, use of a generic medication, or classification
Test Generator Questions, Chapter 1, Introduction to Drugs
Format: Multiple Choice
Chapter: 1
Client Needs: Physiological Integrity: Pharmacological and
Parenteral Therapies
Cognitive Level: Analyze
Difficulty: Moderate
Integrated Process: Nursing Process
Objective: 1
Page and Header: 3, Introduction
1. A nurse working in radiology administers iodine to a client
who is having a computed tomography (CT) scan. The nurse working on the
oncology unit administers chemotherapy to clients who have cancer. At the Public
Health Department, a nurse administers a measles–mumps–rubella (MMR)
vaccine to a 14-month-old child as a routine immunization. Which branch of
pharmacology best describes the actions of all three nurses?
A) pharmacoeconomics
B) pharmacotherapeutics
C) pharmacodynamics
D) pharmacokinetics
Ans: B
Feedback: Pharmacology is the study of the biologic effects of chemicals. Nurses
are involved with clinical pharmacology or pharmacotherapeutics, which is a
branch of pharmacology that deals with the uses of drugs to treat, prevent, and
diagnose disease. The radiology nurse is administering a drug to help diagnose a
disease. The oncology nurse is administering a drug to help treat a disease.
Pharmacoeconomics includes any costs involved in drug therapy.
Pharmacodynamics involves how a drug affects the body, and pharmacokinetics
is how the body acts on the body.
Format: Multiple
, Test Bank For Karch's Focus on Nursing Pharmacology, Ninth Edition Rebecca Tucker
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Cognitive Level: Understand
Difficulty: Easy
Integrated Process: Nursing Process
Objective: 3
Page and Header: Legal Regulation of Drugs, 19, Box 1.2
2. The care provider has prescribed intravenous hydromorphone, an opioid, for a
client using a client-controlled analgesia (PCA) pump. The nurse is aware that
this drug has a high abuse potential. Under what category would hydromorphone
be classified?
A) schedule I
B) schedule II
C) schedule III
D) shedule IV
Ans: B
Feedback: Opioids with a high abuse potential are classified as schedule II
drugs because of severe dependence liability. Schedule I drugs have high abuse
potential and no accepted medical use. Schedule III drugs have a lesser abuse
potential than schedule II drugs and an accepted medical use. Schedule IV drugs
have low abuse potential and limited dependence liability.
Format: Multiple Choice
Chapter: 1
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Cognitive Level: Apply
Difficulty: Moderate
Integrated Process: Nursing Process
Objective: 2
Page and Header: 14, Drug Evaluation
3. When involved in phase III drug evaluation studies, what action should the
nurse perform?
A) Work with animals which are given experimental drugs.
, Test Bank For Karch's Focus on Nursing Pharmacology, Ninth Edition Rebecca Tucker
B) Select appropriate clients to be involved in the drug study.
C) Monitor and observe clients closely for adverse effects.
D) Make decisions that will determine effectiveness of the drug.
Ans: C
Feedback: Phase III studies involve use of a drug in a larger sample of the
population. The purpose is to determine the treatment benefit and to monitor
side effects that may not have been apparent in the earlier studies. Phase I
studies involve healthy human volunteers who are usually paid for their
participation. Nurses may observe for adverse effects and toxicity. Nurses may
be responsible for helping collect and analyze the information to be shared with
the Food and Drug Administration (FDA) but would not conduct research
independently because nurses do not prescribe medications. Use of animals in
drug testing is done in the preclinical trials. Select clients who are involved in
phase II studies have the disease the drug is intended to treat. These clients are
monitored closely for drug action and adverse effects.
Format: Multiple Choice
Chapter: 1
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Cognitive Level: Analyze
Difficulty: Moderate
Integrated Process: Nursing Process
Objective: 4
Page and Header: 22, Legal Regulation of Drugs
4. What concept is prioritized when a provider is considering the substitution of
brand name drug with a generic drug?
A) bioequivalency
B) critical concentration
C) distribution
D) half-life
Ans: A
, Test Bank For Karch's Focus on Nursing Pharmacology, Ninth Edition Rebecca Tucker
Feedback: The goal is that the generic medication is bioequivalent (has the
same effect on the body) to the brand name medication. Binders used in a
generic drug may not be the same as those used in the brand name drug.
Therefore, the way the body breaks down and uses the drug may differ, which
may eliminate a generic drug substitution. Critical concentration is the amount of
a drug that is needed to cause a therapeutic effect and should not differ between
generic and brand name medications. Distribution is the phase of
pharmacokinetics, which involves the movement of a drug to the body’s tissues
and is the same in generic and brand name drugs. A drug’s half-life is the time it
takes for the amount of drug to decrease to half the peak level, which should not
change when substituting a generic medication.
Format: Multiple Choice
Chapter: 1
Client Needs: Physiological Integrity: Pharmacological and Parenteral Therapies
Cognitive Level: Apply
Difficulty: Moderate
Integrated Process: Nursing Process
Objective: 5
Page and Header: 23, Legal Regulation of Drugs
5. A nurse is assessing the client’s home medication use. After listening to the
client list current medications, the nurse asks what priority question?
A) “Do you take any generic medications?”
B) “Are any of these medications orphan drugs?”
C) “Are these medications safe to take during pregnancy?”
D) “Do you take any over-the-counter medications?”
Ans: D
Feedback: It is important for the nurse to specifically question use of over-the-
counter medications because clients may not consider them important. The client
is unlikely to know the meaning of “orphan drugs” unless they are a healthcare
provider. Safety during pregnancy, use of a generic medication, or classification
