Pharm II week 8 CCBs Exam Questions And
Answers Latest 2025
CCBs bind to the (alpha/beta) (1 or 2) subtype of (D/L)-type calcium
channels, causing channels to remain (active/inactive),
(increasing/decreasing) entry of Ca++ into cells -
correct answer ✅bind to alpha1 subtype of L-type calcium
channels, causing channels to remain inactive, decreasing entry of
calcium ions into cells
In cardiac myocytes, calcium (enters/leaves) the cell via the (D/L)
type calcium channel -
correct answer ✅enters the cell via L-type Ca++ channel
Calcium entering the cell triggers the release of more calcium from
the ________________ via ___________ receptors -
correct answer ✅SR via ryanodine receptors
Smooth muscle contraction is dependent on (D/L) type channels for
(increased/decreased) entry of Ca++ into the cell -
correct answer ✅L-type channels for increased entry
Where is troponin in smooth muscle? -
correct answer ✅smooth muscle does not contain the calcium-
binding protein troponin
, Pharm II week 8 CCBs Exam Questions And
Answers Latest 2025
Smooth muscle contraction is initiated by a calcium-regulated
phosphorylation of ______________, rather than a calcium-
activated troponin system -
correct answer ✅myosin
4 broad uses of CCBs -
correct answer ✅-HTN (arterial vasodilation)
-vasospasm (coronary vasodilation)
-angina
-SVT (non-dihydropyridines)
How do CCBs treat angina? (2) -
correct answer ✅-decrease MO2 demand from decreased SVR
-increased MO2 supply from coronary vasodilation
Name the 3 classes of CCBs -
correct answer ✅-dihydropyridines
-non-dihydropyridines: benzothiazepines, and phenylalkylamines
Answers Latest 2025
CCBs bind to the (alpha/beta) (1 or 2) subtype of (D/L)-type calcium
channels, causing channels to remain (active/inactive),
(increasing/decreasing) entry of Ca++ into cells -
correct answer ✅bind to alpha1 subtype of L-type calcium
channels, causing channels to remain inactive, decreasing entry of
calcium ions into cells
In cardiac myocytes, calcium (enters/leaves) the cell via the (D/L)
type calcium channel -
correct answer ✅enters the cell via L-type Ca++ channel
Calcium entering the cell triggers the release of more calcium from
the ________________ via ___________ receptors -
correct answer ✅SR via ryanodine receptors
Smooth muscle contraction is dependent on (D/L) type channels for
(increased/decreased) entry of Ca++ into the cell -
correct answer ✅L-type channels for increased entry
Where is troponin in smooth muscle? -
correct answer ✅smooth muscle does not contain the calcium-
binding protein troponin
, Pharm II week 8 CCBs Exam Questions And
Answers Latest 2025
Smooth muscle contraction is initiated by a calcium-regulated
phosphorylation of ______________, rather than a calcium-
activated troponin system -
correct answer ✅myosin
4 broad uses of CCBs -
correct answer ✅-HTN (arterial vasodilation)
-vasospasm (coronary vasodilation)
-angina
-SVT (non-dihydropyridines)
How do CCBs treat angina? (2) -
correct answer ✅-decrease MO2 demand from decreased SVR
-increased MO2 supply from coronary vasodilation
Name the 3 classes of CCBs -
correct answer ✅-dihydropyridines
-non-dihydropyridines: benzothiazepines, and phenylalkylamines
