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NR 507 midterm Questions and Answers 2025

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Exam of 15 pages for the course NR 507 at NR 507 (NR 507 midterm)

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NR 507 midterm

Hives (urticaria) are an example of a: - answer Type 1 hypersensitivity reaction.

Anaphylaxis is what type of reaction? - answer type 1 hypersensitivity

Which of the following are considered the "first responders" of the innate immune
system? - answer neutrophils

Allergic contact dermatitis is an example of what type of
hypersensitivity reaction. - answer type 4 hypersensitivity reaction

Type 2 (Cytotoxic) hypersensitivity reactions are mediated by: - answer IgG or IgM

Type 1 hypersensitivity reaction is mediated by – answer IgE

Allergic asthma is an example of - answertype 1 hypersensitivity reaction

type 2 hypersensitivity - answertissue specific

Primary effector cells of type 2 - answermacrophages

Examples of type 2 reactions - answerdrug allergies, hemolytic anemia, blood
transfusion mismatch, allergies against infectious agents

Type 2 causes - answerThe cell to be destroyed by the antibody
Cell destruction through phagocytosis by macrophages
Damage to the cell by neutrophils triggering phagocytosis
Natural killer cells to release toxic substances that destroy the target cell
Malfunction of the cell without destruction

Type 3 hypersensitivity reaction - answerantigen-antibody response

Where does the antibody bind to the antigen in type 3 response? - answerin blood or
body fluids and then circulates to tissue

Where does the antibody bind to the antigen in type 1, 2, and 4? - answeron cell surface

Primary effector cell in type 3 - answerneutrophils

example of type 3 reaction - answerserum sickness

, type 4 hypersensitivity reaction - answercell-mediated response

primary mediators of type 4 - answerlymphocytes and macrophages

type 4 mediated by - answerT lymphocytes and do not use antibodies

example of type 4 - answerlocalized contact dermatitis (poison ivy)

Damage occurs with ABO incompatibility because: - answerComplement damages RBC
membrane causing cell lysis.

Which of the following is the underlying pathology for hay fever? - answermast cell
degranulation

The diagnosis for an individual who presents to the office with sudden swollen lips and
eyes, shortness of breath and throat tightness after a bee sting is: - answeranaphylaxis

Which of the following assessment findings would be expected in a patient who
presents with urticaria? - answerEosinophilia.

An example of a primary immunodeficiency is: - answerChronic Granulomatous
Disease.

what is a predominant cause of secondary immune deficiencies worldwide. -
answerMalnutrition

Which of the following is an autoimmune disease? - answerSystemic Lupus
Erythematosus (SLE).

Which is true about a primary immunodeficiency? - answerIt is the result of a single
gene defect. (genetics)

Examples of secondary immunodeficiency - answerHIV, cancer

Secondary immunodeficiency caused by - answerexternal to immune system

examples of primary immunodeficiency - answerChronic granulomatous Disease of
Childhood
DiGeorge Syndrome
Familial Mediterranean fever
Job Syndrome
Common Variable Immunodeficiency

examples of secondary immunodeficiency - answerHuman Immunodeficiency Virus
Pneumocystis Carinii
Pneumonia

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