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NAPLEX antibiotics Questions and Correct Detailed Answers (Verified Answers) ||Already Graded A+||Newest Version

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NAPLEX antibiotics Questions and Correct Detailed Answers (Verified Answers) ||Already Graded A+||Newest VersionNAPLEX antibiotics Questions and Correct Detailed Answers (Verified Answers) ||Already Graded A+||Newest Version

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NAPLEX Antibiotics

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NAPLEX antibiotics

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NAPLEX antibiotics Questions and Correct Detailed
Answers (Verified Answers) ||Already Graded
A+||Newest Version
Quiz: MIC

Ans: lowest drug concentration that prevents visibile microbial growth in 24
hours

Quiz: gram (+) bacteria species

Ans: staph, strep, EC, clostridium, listeria

Quiz: which antibiotics exhibit time-dependent killing?

Ans: penicillins, cephalosporins

Quiz: how can you increase the killing of a time-dependent antibiotic?

Ans: dose more frequently, extend the infusion time

Quiz: example of concentration-dependent antibiotic?

Ans: aminoglycosides (gentamicin, tobramycin, amikacin)

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, Quiz: what are the bacteriostatic antibiotics (protein synthesis inhibitors)?

Ans: macrolides

aminoglycosides

tetracyclines

clindamycin

linezolid

quinupristin, dalfopristin

Quiz: what is the MOA of penicillins, cephalosporins, carbapenems, and

vancomycin?

Ans: cell wall inhibitors - bactericidal

Quiz: what general ADRs are the black box warning for aminoglycosides?

Ans: nephrotoxicity and neurotoxicity

Quiz: what are the aminoglycosides?

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, Ans: tobramycin

gentamicin

amikacin

Quiz: what type of nephrotoxicity do aminoglycosides cause?

Ans: ATN - acute tubular necrosis

Quiz: what weight do you use to dose aminoglycosides?

Ans: IBW (unless TBW is less)

*use ABW if obese ( > 30% IBW)

Quiz: what organisms are aminoglycosides mainly active against?

Ans: gram (-): GNR, PA

Quiz: extended interval dosing of the aminoglycosides?

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, Ans: gent/tobra: 4-7 mg/kg

amikacin: 15-20 mg/kg

*draw random level within 6-16 hours after dose

Quiz: adjust body weight (ABW) formula?

Ans: IBW + [0.4(TBW - IBW)]

Quiz: desired trough (traditional dosing) for gent/tobra? peak?

Ans: trough: < 2 mcg/mL

peak: 5-10 mcg/mL

Quiz: amoxicilin brand name

Ans: Amoxil

Quiz: what organisms do the penicillins cover?

Ans: mainly gram (+), some gram (-)

Quiz: which penicillin is the DOC in acute otitis media?

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